|   |
79 | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | |
120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
N | G | N | E | Q | Q | W | L | E | L | E | S | A | A | C | Q | Y | E | E | N | L | L | P | P | F | Y | D | T | L | T | Q | Y | V | E | M | G | N | S | T | F | A | . |
C | P | G | H | Q | H | G | A | F | F | K | K | H | P | A | G | R | H | F | Y | D | F | F | G | E | N | V | F | R | A | D | M | C | N | A | D | V | K |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|
|
|   |   |
|
|   |   |
|   |   |   |   |   |   |
|
|
| . |   |
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |
|
|
|   |
|   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
| . |
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|
|   |   |   |
|
|   |   |
|   |   |
|
|   |   |   |
|   |
|
|
|
|
| . | . | . | . | . | . | . | . |
|   |   |
|   |   |
|   |   |
|
|   | . |
|   |
|   |   |
|
|
| . |   |
|   |
|
Template Sequence |   |
D | R | D | A | T | L | W | A | S | H | E | K | X | L | S | Q | P | L | K | D | S | D | A | E | V | Y | S | I | I | K | K | E | S | N | R | Q | R | V | G | L | E | L | I | A | S | E | . |
. |
. |
. |
. |
. |
. |
. |
N | F | A | S | R | A | V | L | E | A | L | G | . |
S | S | L | N | N | K | Y | S | . |
E | G | Y | P |
Template Known Secondary structure |   |
S | S | S |  |  |  |  |  |  |  |  |  |  | T | T | S |
|  |  |  |  | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | S | S |  |  |
|
| T | T |
| . | . | . | . | . | . | . | . |
|
|
|
|  |  |  |  |  |  |  | T | . | S | G | G | G | G |
|
|
| . |
| S |
| S |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|  |  |  |  |  |  |  |  | . |  |  |  |  |
|
|
|
| . |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
9 | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | |
|
|
|
|
|
|
|
. | . | . | . | . | 60 | . | . | . | . | . | . | |
. | . | . | 70 | . | . | . | . | |
. | . | . | . |
  |
  |   |
158 | . | 160 | . | . | . | . | . | . | . | . | . | 170 | |
|
|
|
. | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | |
|
|
|
190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|  |  |  |  |  | . | . | . | . |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
| . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | G | D | L | L | I | H | E | G | S | A | K | D | . |
. |
. |
. |
A | Q | K | F | A | A | K | V | F | H | A | D | K | T | Y | F | V | L | N | . |
. |
. |
. |
G | T | S | A | A | N | K | V | V | T | N | A | L | L | T | R | G | D | L | V | L | F | D | R | N | N | H | K | S | N | H | H | G | A | L | I | Q | A | G | A |
Query Conservation |   |
|
|
|
|   |   |
|   |
|   |
|   |
| . | . | . | . |
|
|   |
|
|
|   |   |
|
|
|   |   |
|   |
|
|
|
| . | . | . | . |
|
|
|   |
|
|   |
|   |
|   |
|   |   |   |   |
|
|   |
|
|
|   |
|
|   |
|
|
|
|   |   |
|
|
|
|
|
|
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
Template Conservation |   |
|   |
|   |   |   |
|   |   |   |
|
|   |
|
|   |   |   |   |
|   |
|   |   |
|
|   |   |   |   |   |   |   |   |   |
|
|
|
|   |
|
|   |   |
|
|   |
|
|   |   |
|
|   |   |
|
|
|   |
|
|   |   |   |   |   |   |
|
|
|   |
|   | . |   |   |   |   |   |   |
Template Sequence |   |
G | Q | R | Y | Y | G | G | T | E | F | I | D | E | L | E | X | L | C | Q | K | R | A | L | Q | A | Y | H | L | D | P | Q | C | W | G | V | N | V | Q | P | Y | S | G | S | P | A | N | F | A | V | Y | T | A | L | V | E | P | H | G | R | I | X | G | L | D | L | P | D | G | G | H | L | T | H | . |
G | F | X | T | D | K |
Template Known Secondary structure |   |
S | S |
| S | S | S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
| T | T | T |  |  |  |  |
|
|
| S | S |  |  |  |  |  |  |  |  |  |  |  |  | T |
| T | T |
|  |  |  |  |  |
| G | G | G | T |
|
| G | G | G | . |
|
| B |
| S | S |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |
|  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|  | . |  |  |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
79 | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | |
. | . | . | . | . | . |
  |
  |   |
230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | |
. | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
T | P | V | Y | L | E | A | S | R | N | P | F | G | F | I | G | G | I | . |
D | A | H | C | F | N | E | E | Y | L | R | Q | Q | I | R | D | V | A | P | E | K | A | D | L | P | R | P | Y | R | L | A | I | I | Q | L | G | T | Y | D | G | T | V | Y | N | A | R | Q | V | I | D | T | V | G | H | L | C | D | Y | I | L | F |
Query Conservation |   |
  |
|
|
|
|   |
|   |   |   |   |   |
|   |
|
|   |
| . |   |   |   |   |
|
|   |
|   |
|   |   |   |
|   |   |   |
|   |   |
|
|   |   |   |   |   |   |   |   |
|
|
|
|
|
|
|
|   |
|
|   |   |
|
|   |   |
|   |   |   |   |
|   |   |   |   |   |
|
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|
|   |
|   |
|   |   |   |   |   |   |   |   |
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|   |   |   |
|   |   |   |   |   |   |
|   |   |   |
|   |
|
|   |   |   |   |
|
|   |
|   |   |
Template Sequence |   |
K | K | I | S | A | T | S | I | F | F | E | S | X | P | Y | K | V | Y | P | E | T | G | Y | I | N | Y | D | Q | L | E | E | N | A | S | L | F | H | P | K | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
L | I | I | A | G | T | S | C | Y | S | R | N | L | D | Y | A | R | L | R | K | I | A | D | D | N | G | A | Y | L | X | A |
Template Known Secondary structure |   |
| B |
| S |  |  |  |  |  | S |  |  |  |  |  |
| B |
| T | T | T |
| S | B |
|  |  |  |  |  |  |  |  |  |  |  |
|
| S | . | . | . | . | . | . | . | . | . | . |  |  |  |  |
|
| S | S |
|
| S |
|
|
|  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
| . | . | . | . | . | . | . | . | . | . |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
158 | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
. | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . |
  |
  |   |
309 | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | |
|
|
|
|
. | . | . | . | . | . | 380 | . | . | . |
Predicted Secondary structure |   |
 |
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
D | S | A | W | V | G | Y | E | Q | F | I | P | M | M | A | D | S | S | P | L | L | L | E | L | N | E | N | D | P | G | I | F | V | T | Q | S | V | H | K | Q | Q | A | G | F | S | Q | T | S | Q | I | H | K | K | D | N | H | I | R | G | Q | A | R | F | C | P | . |
. |
. |
. |
. |
H | K | R | L | N | N | A | F | M | L |
Query Conservation |   |
|
|
|
|
|
|
|   |   |
|
|
|   |   |   |   |   |
|   |   |
|
|   |   |
|
|
|   |   |   |
|
|
|
|
|
|   |
|
|
|
|
|
|
|
|
|
|
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |
|
| . | . | . | . | . |   |   |
|
|   |   |
|
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
| . |
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |
|
|   |   |
|
|
|   |   | . | . | . | . |   |   |   |
|   |
|
|   | . |   |
|
| . | . | . | . |
|
|   |   |
|
|
|
|
|
|   |
|
|   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|
|   |
|
Template Sequence |   |
D | X | A | H | I | S | G | L | V | A | A | . |
. |
. |
. |
G | V | V | P | S | P | F | E | . |
H | C | H | . |
. |
. |
. |
V | V | T | T | T | T | H | K | T | L | R | G | C | R | A | G | X | I | F | Y | R | K | G | V | R | S | V | D | P | K | T | G | K | E | T | Y | Y | E | L | E | S | L | I | N | S | A | V | F | P |
Template Known Secondary structure |   |
 |
| G | G | G |  |  |  |  |  | T | . | . | . | . | T | S | S |
|
| G | G | G | . | T |
| S | . | . | . | . |  |  |  |  |  | S | S | G | G | G |
|
|
| S |
|  |  |  |  |  |  |
|  |  |  |  |  |
| S | T | T |
|
|  |  |  |  |
|  |  |  |  |  |  |  |  |  | T | T |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
| . |
|
|  | . | . | . | . |  |  |  |  |  |
|  |  |
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
228 | . | 230 | . | . | . | . | . | . | . | . | |
|
|
|
. | 240 | . | . | . | . | . | . | |
. | . | . | |
|
|
|
250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . |
  |
  |   |
384 | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . |
Predicted Secondary structure |   |
 |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
H | A | S | T | S | P | F | Y | P | L | F | A | A | L | D | V | N | A | K | I | H | E | G | E | S | G | R | R | L | W | A | E | C | V | E | I | G | I | E | A | R | K | A | I | L | A | R | C | K | L | F | R | P | F | I | P | P | V | V | D | G | K | L | W | Q | D | Y | P | T | S | V | L | A | S | D | R | R | F | F | S |
Query Conservation |   |
  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |
|
|   |   |
|   |   |
|   |
|   |   |
|   |   |   |   |
|   |   |   |   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
  |   |   |   |
|
|   |   |   |   |
|
|
|
|
|
|
|
|   |
|   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |
|
|   |   |
|   |   |   |
|   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Sequence |   |
G | L | Q | G | G | P | H | N | H | A | I | A | G | V | A | V | A | L | K | Q | A | X | T | T | E | F | K | I | Y | Q | L | Q | V | L | A | N | C | R | A | L | S | D | A | L | T | E | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
T | T |
|
| S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
299 | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |
  |   |
464 | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | |
|
|
|
|
|
|
|
|
|
|
|
|
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|  | . | . | . | . | . | . | . | . | . | . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Sequence |   |
F | E | P | G | A | K | W | H | G | F | E | G | Y | A | A | D | Q | Y | F | V | D | P | C | K | L | L | L | T | T | P | G | I | D | A | E | T | G | E | Y | S | D | F | G | V | P | A | T | I | L | A | H | Y | L | R | E | N | G | I | V | P | E | K | C | D | L | N | S | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Conservation |   |
  |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|   |
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |   |
|   |   |   |
|   |
|   |
|
|   |   |
|   |
|
|   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . |
Alig confidence |   |
. | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
. | . | . | . | . | . | . |   |
|   |   |
|   |   |
|
|
| . | . | . |
|   |
|   |
|
|
|
|   | . | . | . | . | . | . | . | . | . | . |   |   |   |
|
|   |
|   |   |   |   |   |   |
|
|   |   |   |
|   |   |
|   |   |   |
|
|   |
|   |   |   |   |   |   |   |
|
|
|
|
|
Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
L | G | Y | K | I | V | T | G | G | S | . |
. |
. |
D | N | H | L | I | L | X | D | L | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
R | S | K | G | T | D | G | G | R | A | E | K | V | L | E | A | C | S | I | A | C | N | K | N | T | C | P | G | D | K | S | A | L | R | P | S | G | L | R | L | G |
Template Known Secondary structure |   |
. | . | . | . | . | . | . | T | T |
|
| B | T | T | S | S |
| . | . | . | S | S | S |  |  |  |  |  | G | . | . | . | . | . | . | . | . | . | . | G | G | G | T |
|
|  |  |  |  |  |  |  |  |  |  | T | T |  |  |
| B |
|
|
|
| S | S | S | S |
| T | T | S |
| S |  |  |  |  |  |
Template Predicted Secondary structure |   |
. | . | . | . | . | . | . |
|
|
|  |  |  |
|
|
|
| . | . | . |
|
|
|  |  |  |  |
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
|
|
345 | . | . | . | . | 350 | . | . | . | . | |
|
|
. | . | . | . | . | 360 | . | . | . | |
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . |
  |
  |   |
531 | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . | . | . | . | . | . | . | 610 |
Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
I | L | F | L | L | T | P | A | E | S | H | E | K | L | A | Q | L | V | A | M | L | A | Q | F | E | Q | H | I | E | D | D | S | P | L | V | E | V | L | P | S | V | Y | N | K | Y | P | V | R | Y | R | D | Y | T | L | R | Q | L | C | Q | E | M | H | D | L | Y | V | S | F | D | V | K | D | L | Q | K | A | M | F | R | Q |
Query Conservation |   |
|
|   |
|   |
|   |
|   |
|   |   |
|   |   |   |
|   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
Template Conservation |   |
|   |   |   |
|   |
|
|   |   |   |   |
|   |   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |
Template Sequence |   |
T | P | A | L | T | S | R | G | L | L | E | E | D | F | Q | K | V | A | H | F | I | H | R | G | I | E | L | T | L | Q | I | Q | S | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
H |
Template Known Secondary structure |   |
|  |  |  |  | T | T | T |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | T |
Template Predicted Secondary structure |   |
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
405 | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. |
  |
  |   |
611 | . | . | . | . | . | . | . | . | 620 | . | . | . | . | . | . | . | . | . | 630 | . | . | . | . | . | . | . | . | . | 640 | . | . | . | . | . | . | . | . | . | 650 | . | . | . | |
. | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
| . |
|
|
|  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
Query Sequence |   |
Q | S | F | P | S | V | V | M | N | P | Q | D | A | H | S | A | Y | I | R | G | D | V | E | L | V | R | I | R | D | A | E | G | R | I | A | A | E | G | A | L | P | Y | P | . |
P | G | V | L |
Query Conservation |   |
  |   |   |
|   |   |   |
|   |
|
|
|
|   |   |
|   |   |   |   |   |   |
|   |
|
|
|   |
|
|   |
|
|
|
|
|
|   |
|   |
|
|
| . |
|
|
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |   |
|
|   |
|
|   |   |
Template Sequence |   |
X | A | T | K | A | T | L | K | E | F | K | E | K | L | A | G | . |
. |
. |
. |
D | E | K | I | Q | S | A | V | A | T | L | R | E | E | V | E | N | F | A | S | N | F | S | L | P | G | L | P |
Template Known Secondary structure |   |
T |
| S | S |
|
|  |  |  |  |  |  |  |  |  | S | . | . | . | . |
| S | T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | S |
|
|
| S | S | S |
Template Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
| . | . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
439 | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | |
|
|
|
. | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . |
  |