Job Description P0AB77 Confidence 99.97% Date Thu Jan 5 11:14:48 GMT 2012 Rank 99 Aligned Residues 367 % Identity 12% Template c3e9kA_ PDB info PDB header:hydrolase Chain: A: PDB Molecule:kynureninase; PDBTitle: crystal structure of homo sapiens kynureninase-3-hydroxyhippuric acid2 inhibitor complex Resolution 1.70 Å

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		7	.	.	10	.	.	.	.	.	.						.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.
Predicted Secondary structure												.	.	.	.	.
Query SS confidence												.	.	.	.	.
Query Sequence		Q	Q	L	T	N	D	L	E	T	A	.	.	.	.	.	R	A	E	G	L	F	K	E	E	R	I	I	T	S	A	Q	Q	A	D	I	T	V	A	D	G	S	H	V	I	N	F	C	A	N	N	Y	L	G	L	A	N	H	P	D	L	I	A	A	A	K	A	G	M	D	S	H	G	F	G	M	A	S	V	R	F
Query Conservation												.	.	.	.	.
Alig confidence												.	.	.	.	.																																		.	.	.			.
Template Conservation																																																		.	.	.			.
Template Sequence		E	R	V	A	L	H	L	D	E	E	D	K	L	R	H	F	R	E	F	Y	I	P	K	I	Q	D	L	P	P	V	D	L	S	L	V	N	K	D	E	N	A	I	Y	F	L	G	N	S	.	.	.	L	G	.	L	Q	P	K	M	V	K	T	Y	L	E	E	E	L	D	K	W	A	K	I	A	A	Y	G	H	E
Template Known Secondary structure											T		T	T	G	G	G	G			B			B	G	G	G	S	T	T			G	G	G	S		T	T		B					B	T	T	T	.	.	.	S		.		B		T	T																G	G	G	G	G	T
Template Predicted Secondary structure																																																		.	.	.			.
Template SS confidence
		27	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.				.	.		.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.
		82	.	.	.			.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.			.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.				.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.
Predicted Secondary structure						.	.																		.	.																								.	.	.																						.	.	.	.	.	.	.	.
Query SS confidence						.	.																		.	.																								.	.	.																						.	.	.	.	.	.	.	.
Query Sequence		I	C	G	T	.	.	Q	D	S	H	K	E	L	E	Q	K	L	A	A	F	L	G	M	.	.	E	D	A	I	L	Y	S	S	C	F	D	A	N	G	G	L	F	E	T	L	L	G	A	.	.	.	E	D	A	I	I	S	D	A	L	N	H	A	S	I	I	D	G	V	R	L	C	.	.	.	.	.	.	.	.
Query Conservation						.	.																		.	.																								.	.	.																						.	.	.	.	.	.	.	.
Alig confidence						.	.																		.	.																								.	.	.																						.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		V	G	K	R	P	W	I	T	G	D	E	S	I	V	G	L	M	K	D	I	V	G	A	N	E	K	E	I	A	L	M	N	A	L	T	V	N	L	H	L	L	M	L	S	F	F	K	P	T	P	K	R	Y	K	I	L	L	E	A	K	A	F	P	S	D	H	Y	A	I	E	S	Q	L	Q	L	H	G	L	N	I
Template Known Secondary structure		S	S	S	S		G	G	G	T	T					G	G	G					T			G	G	G					S																		S	S	S							T	T																T	T
Template Predicted Secondary structure
Template SS confidence
		104	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.
			147	.	.	150	.	.	.	.	.	.	.	.	.			160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.
Predicted Secondary structure		.														.	.
Query SS confidence		.														.	.
Query Sequence		.	K	A	K	R	Y	R	Y	A	N	N	D	M	Q	.	.	E	L	E	A	R	L	K	E	A	R	E	A	G	A	R	H	V	L	I	A	T	D	G	V	F	S	M	D	G	V	I	A	N	L	K	G	V	C	D	L	A	D	K	Y	D	A	L	V	M	V	D	D	S	H	A	V	G	F	V	G	E	N	G	R
Query Conservation		.														.	.
Alig confidence		.														.	.
Template Conservation
Template Sequence		E	E	S	M	R	M	I	K	P	R	E	G	E	E	T	L	R	I	E	D	I	L	E	V	I	E	K	E	G	D	S	I	A	V	I	L	F	S	G	V	H	F	Y	T	G	Q	H	F	N	I	P	A	I	T	K	A	G	Q	A	K	G	C	Y	V	G	F	D	L	A	H	A	V	G	N	V	E	L	Y	L	H
Template Known Secondary structure												T	T		S	S														G	G	G								S	B		T	T	T		B	B													T	T								T	T	T	T	T	T	S
Template Predicted Secondary structure
Template SS confidence
		184	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.
		224	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.																										.	.	.	.	.	.	.
Predicted Secondary structure																																																		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence																																																		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		G	S	H	E	Y	C	D	V	M	G	R	V	D	I	I	T	G	T	L	G	K	A	L	G	G	A	S	G	G	Y	T	A	A	R	K	E	V	V	E	W	L	R	Q	R	S	R	P	Y	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	L	F	S	N	S	L	A
Query Conservation																																																		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence		.	.	.	.	.	.																																											.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation		.	.	.	.	.	.
Template Sequence		.	.	.	.	.	.	D	W	G	V	D	F	A	C	W	C	S	Y	K	Y	L	N	A	G	A	G	G	I	A	G	A	F	I	H	E	K	H	A	H	T	I	K	P	A	L	V	G	W	F	G	H	E	L	S	T	R	F	K	M	D	N	K	L	Q	L	I	P	G	V	C	G	F	R	I	S	N	P	P	I	L
Template Known Secondary structure		.	.	.	.	.	.			T								S	S	S	T	T				T	T									G	G	G	T	T	T	S			S	S			G	G	G	B						T	T			S				B		S	S	G	G	G	G			S
Template Predicted Secondary structure		.	.	.	.	.	.
Template SS confidence
								264	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.
		279	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320								.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.
Predicted Secondary structure																																												.	.	.	.	.	.	.
Query SS confidence																																												.	.	.	.	.	.	.
Query Sequence		P	A	I	V	A	A	S	I	K	V	L	E	M	V	E	A	G	S	E	L	R	D	R	L	W	A	N	A	R	Q	F	R	E	Q	M	S	A	A	G	F	T	L	.	.	.	.	.	.	.	A	G	A	D	H	A	I	I	P	V	M	L	G	D	A	V	V	A	Q	K	F	A	R	E	L	Q	K	E	G	I	Y
Query Conservation																																												.	.	.	.	.	.	.
Alig confidence																																												.	.	.	.	.	.	.															.	.
Template Conservation																																																																	.	.
Template Sequence		L	V	C	S	L	H	A	S	L	E	I	F	K	Q	A	T	M	K	A	L	R	K	K	S	V	L	L	T	G	Y	L	E	Y	L	I	K	H	N	Y	G	V	V	N	I	I	T	P	S	H	V	E	E	R	G	C	Q	L	T	I	T	F	S	V	.	.	P	N	K	D	V	F	Q	E	L	E	K	R	G	V	V
Template Known Secondary structure																																															S		S	S	G	G	G	B		S									.	.	T	T									T	T	T
Template Predicted Secondary structure																																																																	.	.
Template SS confidence
		338	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400			.	.	.	.	.	.	.	.	.	410	.	.	.	.	.
		352	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.		.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.
Predicted Secondary structure																						.
Query SS confidence																						.
Query Sequence		V	T	G	F	F	Y	P	V	V	P	K	G	Q	A	R	I	R	T	Q	M	.	S	A	A	H	T	P	E	Q	I	T	R	A	V	E	A	F	T	R	I	G	K
Query Conservation																						.
Alig confidence								.	.	.	.	.	.	.								.
Template Conservation								.	.	.	.	.	.	.
Template Sequence		C	D	K	R	N	P	.	.	.	.	.	.	.	N	G	I	R	V	A	P	V	P	L	Y	N	S	F	H	D	V	Y	K	F	T	N	L	L	T	S	I	L	D
Template Known Secondary structure						T	T	.	.	.	.	.	.	.	T					B			T	T	T																		T
Template Predicted Secondary structure								.	.	.	.	.	.	.
Template SS confidence
		425	.	.	.	.	430								.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.