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Job DescriptionP37689
Confidence99.67%DateThu Jan 5 11:57:01 GMT 2012
Rank21Aligned Residues147
% Identity13%Templatec2xrgA_
PDB info PDB header:hydrolaseChain: A: PDB Molecule:ectonucleotide pyrophosphatase/phosphodiesterase family PDBTitle: crystal structure of autotaxin (enpp2) in complex with the2 ha155 boronic acid inhibitor
Resolution3.20 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   364.....370.........380....... ..390.........400.........410. ........420.........430....
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Query Sequence  KVATYDLQPEMSSAELTEKLVAAI. . . KSGKYDTIICNYPNGDMVGHTGVM. . EAAVKAVEALDHCVEEVAKAVES. . . .
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Template Sequence  RAGTFFWSVSIPHERRILTILQWLSLPDNERPSVYAFYSEQPDFSGHKYGPFGPEMTNPLREIDKTVGQLMDGLKQLRLH
Template Known Secondary structure 
B





TTS
TTS
TTT

S
TT
GGGTT
T
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   269270.........280.........290.........300.........310.........320.........330.........340........
 
   435....440.........
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Query Sequence  VGGQLLITADHGNAE. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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Template Sequence  RCVNVIFVGDHGMEDVTCDRTEFLSNYLTNVDDITLVPGTLGRIRAKYDPKTIIAALTCKKPDQHFKPYMKQHLPKRLHY
Template Known Secondary structure  TT
S




SSSGGGT
S

TT
BS


TTSS
STT

GGGS
GGG

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   349350.........360.........370.........380.........390.........400.........410.........420........
 
   450.........460.........470........ .480.........490......... 500......
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Query Sequence  . . . . . . . . . . . . . . . . . . . . QMRDPATGQAHTAHTNLPVPLIYVGDKNV. . KAVEGGKLSDIAPTMLSLMGM. EIPQEMT
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Template Sequence  ANNRRIEDIHLLVDRRWHVARKPFQGDHGFDNKVNSMQTVFVGYGPTFKYRTKVPPFENIELYNVMCDLLGLKPAPNNGT
Template Known Secondary structure 
SSTTS
S
TT
S





S
TT
GGG
B
SSSB
SS
B


GGGT



S
SS
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   435....440.........450.........460.........470.........480.........490.........500.........510....
 
   507..510
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Query Sequence  GKPL
Query Conservation 
 

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Template Conservation     
Template Sequence  HGSL
Template Known Secondary structure  TTTT
Template Predicted Secondary structure 
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   527..530
 
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No model constructed - rank, confidence too low




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Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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