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Job DescriptionP77318
Confidence100.00%DateThu Jan 5 12:27:41 GMT 2012
Rank21Aligned Residues280
% Identity16%Templatec2xrgA_
PDB info PDB header:hydrolaseChain: A: PDB Molecule:ectonucleotide pyrophosphatase/phosphodiesterase family PDBTitle: crystal structure of autotaxin (enpp2) in complex with the2 ha155 boronic acid inhibitor
Resolution3.20 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   44.....50.........60.........70.........80.........90.........100.........110.........120...
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Query Sequence  FSDFTPTEYSTKGKPNIIVLTMDDLGYGQLPFDKGSFDPKTMENREVVDTYKIGIDKAIEAAQKSTPTLLSLMDEGVRFT
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Template Sequence  EEIKVPECPAGFVRPPLIIFSVDGFRASYMKKGSKV. . . . . . . . . . . . . . . . . . . . . . . . . . . . . MPNIEKLRSCGTHAP
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S



TT
SS

T

GGGGGS
TTT.............................SS
S
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   149150.........160.........170.........180.... .....190.........
 
   124.....130 .........140.........150.........160... ......170.........180.......
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Query Sequence  NGYVAHG. VSGPSRAAIMTGRAPARFGVYSNTDAQDGIPLT. . . . . . . . . . . . . . . ETFLPELFQNHGYYTAAVGKWHLS
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Template Sequence  YMRPVYPTKTFPNLYTLATGLYPESHGIVGNSMYDPVFDASFHLRGREKFNHRWWGGQPLWITATKQGVRAGTF. . . . . .
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SS
S
S
S


SSTTTT
SSSSGGG
TTS

S

TTT

B


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   200.........210.........220.........230.........240.........250.........260.........270...
 
   188.190.........200.........210.........220.........230.........240.........250.........260.......
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Query Sequence  KISNVPVPEDKQTRDYHDNFTTFSAEEWQPQNRGFDYFMGFHAAGTAYYNSPSLFKNRERVPAKGYISDQLTDEAIGVVD
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Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . FWSVSIPHERRILTILQWLS
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TTS
TT
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   274.....280.........290...
 
   268.270.........280.........290.........300.........310.........320.........330.........340.......
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Query Sequence  RAKTLDQPFMLYLAYNAPHLPNDNPAPDQYQKQFNTGSQTADNYYASVYSVDQGVKRILEQLKKNGQYDNTIILFTSDNG
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Template Sequence  L. PDNERPSVYAFYSEQPDF. . . . . . . . . . . . SGHKYGPFGPEMTNPLREIDKTVGQLMDGLKQLRLHRCVNVIFVGDHG
Template Known Secondary structure  S.
TTT

S............
TT
GGGTT
TTT
S

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   294 .....300.........310.. .......320.........330.........340.........350.........360
 
   348.350...
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Query Sequence  AVIDGP. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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Template Sequence  MEDVTCDRTEFLSNYLTNVDDITLVPGTLGRIRAKYDPKTIIAALTCKKPDQHFKPYMKQHLPKRLHYANNRRIEDIHLL
Template Known Secondary structure 


SSSGGGT
S

TT
BS


TTSS
STT

GGGS
GGG


SSTTS
S
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   361........370.........380.........390.........400.........410.........420.........430.........440
 
   354.....360.........370.........380.........390.........400.........410......... 420.....
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Query Sequence  . . . . . . LPLNGAQKGYKSQTYPGGTHTPMFMWWKGKLQPGNYDKLISAMDFYPTALDAADISIPKDLKLDGV. . SLLPWL
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Template Sequence  VDRRWHVARKPFQGDHGFDNKVNSMQTVFVGYGPT. FKYRTKVPPFENIELYNVMCDLLGLKPAPN. . . NGTHGSLNHLL
Template Known Secondary structure 
TT
S





S
TT
GGG
B
SSS.B
SS
B


GGGT



S
...SS
TTTTGGGB
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   447..450.........460.........470.........480. ........490.........500.........510. ........520..
 
   426...430.....
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Query Sequence  QDKKQGEPHK
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Template Sequence  RTNTFRPTMP
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   535....540....
 
Download:Text version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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