|   |
14 | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | |
|
|
|
Predicted Secondary structure |   |
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
| . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
Query Sequence |   |
A | K | T | I | I | H | G | D | A | L | A | E | L | K | K | I | P | A | E | S | V | D | L | I | F | A | D | P | P | Y | N | I | G | K | N | F | D | G | L | I | E | A | W | K | E | D | L | F | I | D | W | L | F | E | V | I | A | E | C | H | R | V | L | K | K | Q | G | S | M | Y | I | M | N | S | T | E | . |
. |
. |
. |
Query Conservation |   |
  |   |   |
|   |   |
|
|   |   |
|   |
|   |   |
|   |
|   |
|
|
|
|
|
|
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |   |
|   |
|   |
|   |   |   |   |   | . | . | . | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
Template Conservation |   |
  |   |   |
|   |   |
|
|   |   |
|   |
|   |   |
|   |
|   |
|
|
|
|
|
|
|
|
|
|
|   |   |   |   |   |   |   |   | . | . | . | . | . | . |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |   |
|   |
|   |
|   |   |   |
|   |   |   |   |   |
Template Sequence |   |
V | H | R | L | H | V | G | D | A | R | E | V | L | A | S | F | P | E | A | S | V | H | L | V | V | T | S | P | P | Y | W | T | L | G | H | I | E | D | . |
. |
. |
. |
. |
. |
Y | E | A | F | L | D | E | L | D | R | V | W | R | E | V | F | R | L | L | V | P | G | G | R | L | V | I | V | V | G | D | V | A | V | A | R |
Template Known Secondary structure |   |
|
|  |  |  |  | S |
|  |  |  |  |  |  | T | S |
| T | T |
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |
| T | T |
Template Predicted Secondary structure |   |
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
21 | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
. | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . |
  |
  |   |
|
|
|
|
|
|
|
|
|
|
|
90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . |
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
N | M | P | F | I | D | L | Q | C | R | K | L | F | T | I | K | S | R | I | V | W | S | Y | D | S | S | G | V | Q | A | K | K | H | Y | G | S | M | Y | E | P | I | L | M | M | V | K | D | A | K | N | Y | T | F | N | G | D | A | I | L | V | E | A | K | T | G | S | Q | R | A |
Query Conservation |   |
. | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|
|
|   |
|   |   | . |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . |
Template Sequence |   |
R | R | F | G | R | H | L | V | F | P | L | H | A | D | I | Q | V | R | C | R | K | L | G | F | D | N | L | N | P | I | I | W | H | K | H | T | . |
P | Y | E | P | G | A | I | I | K | T | E | I | E | Y | I | L | M | Q | R | K | P | G | G | Y | R | K | P | T | Q | E | Q | R | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
S | S | S | S | S |
|
|  |  |
|  |  |  |  |  |  |  |  |  |  | T | T | T |
|  |  |  |  |  |  |  |  |  |
|
|
| . |
|
|
| T | T |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
| S |
|
|
|
|
|
|  |  |  |  | . | . | . | . | . | . | . | . | . | . | . |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
105 | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | |
. | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | |
|
|
|
|
|
|
|
|
|
|
  |
  |   |
159 | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | I | D | Y | R | K | N | P | P | Q | P | Y | N | H | Q | K | V | P | G | N | V | W | D | F | P | R | V | R | Y | L | M | D | E | Y | E | N | H | P | T | Q | K | P | E | A | L | L | K | R | I | I | L | A | S | S | N | P | G | D | I | V | L | D | P | F | A | G | S | F | T | T | G | A | V | A | I | A | S | G | R | K |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|
|   |   |
|   |
|   |
|
|   |   |   |
|   |
|
|
|   |
|
|
|
|
|   |
|
|
|
|
|   |   |
|
|   |   |
|
|
|   |
Alig confidence |   |
. | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . |   |   |
|   |   |   |
|
|   |   |
|   |   |   |
|
|   |   |   |
|   |   |
|
|   |
|
|
|
|
|   |
|
|
|
|
|   |   |
|
|   |   |   |   |
|   |
Template Sequence |   |
. |
. |
. |
. |
E | K | S | R | L | P | K | E | D | F | H | R | F | F | R | Q | I | W | D | D | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
I | P | G | E | A | P | F | P | L | E | L | A | E | R | L | V | R | M | F | S | F | V | G | D | V | V | L | D | P | F | A | G | T | G | T | T | L | I | A | A | A | R | W | G | R | R |
Template Known Secondary structure |   |
. | . | . | . |  |  |  |
|
|
|  |  |  |  |  |  |  | S | S | S |  |  |
| S | . | . | . | . | . | . | . | . | . | . | S |
|
|
|
|
| S |
|  |  |  |  |  |  |  |  |  |  |  |
|
| T | T |
|  |  |  |  | T | T |
| T | T | T |  |  |  |  |  |  |  |  | T | T |
|  |
Template Predicted Secondary structure |   |
. | . | . | . |
|
|
|
|
|
|
|
|
|
|
|  |  |
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
188 | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
. | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . |
  |
  |   |
239 | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
F | I | G | I | E | I | N | S | E | Y | I | K | M | G | L | R | R | L | D | V | A |
Query Conservation |   |
  |
|
|
|
|
|   |   |   |
|   |   |   |
|   |   |
|
|   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|
|   |
|   |   |   |   |
|   |   |   |
|   |   |
|   |   |   |   |
Template Sequence |   |
A | L | G | V | E | L | V | P | R | Y | A | Q | L | A | K | E | R | F | A | R | E |
Template Known Secondary structure |   |
 |  |  |  |  | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 |
  |