Job Description P11988 Confidence 99.69% Date Thu Jan 5 11:33:02 GMT 2012 Rank 87 Aligned Residues 269 % Identity 16% Template c3lpgA_ PDB info PDB header:hydrolase/hydrolase inhibitor Chain: A: PDB Molecule:beta-glucuronidase; PDBTitle: structure of e. coli beta-glucuronidase bound with a novel, potent2 inhibitor 3-(2-fluorophenyl)-1-(2-hydroxyethyl)-1-((6-methyl-2-oxo-1,3 2-dihydroquinolin-3-yl)methyl)urea Resolution 2.42 Å

Show / Hide SS confidence

Show / Hide Conservation and Alignment quality

		63	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.
Predicted Secondary structure																																																																																	.
Query SS confidence																																																																																	.
Query Sequence		H	R	Y	P	E	D	I	A	L	F	A	E	M	G	F	T	C	L	R	I	S	I	A	W	A	R	I	F	P	Q	G	D	E	V	E	P	N	E	A	G	L	A	F	Y	D	R	L	F	D	E	M	A	Q	A	G	I	K	P	L	V	T	L	S	H	Y	E	M	P	Y	G	L	V	K	N	Y	G	G	W	A	.
Query Conservation																																																																																	.
Alig confidence																												.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																																				.
Template Conservation																												.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		V	L	X	V	H	D	H	A	L	X	D	W	I	G	A	N	S	Y	R	T	S	H	Y	P	Y	A	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	E	E	X	L	D	W	A	D	E	H	G	I	V	V	I	D	E	T	A	A	V	G	F	N	L	S	L	G	I	G	F	E	A	G	N	K
Template Known Secondary structure															T							T	T	S				.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.											T								S		B				S					S	S	S
Template Predicted Secondary structure																												.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		309	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.																			.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370
												142	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.			.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.
Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.																							.	.
Query SS confidence		.	.	.	.	.	.	.	.	.	.																							.	.
Query Sequence		.	.	.	.	.	.	.	.	.	.	N	R	A	V	I	D	H	F	E	H	Y	A	R	T	V	F	T	R	Y	Q	H	K	.	.	V	A	L	W	L	T	F	N	E	I	N	M	S	L	H	A	P	F	T	G	V	G	L	A	E	E	S	G	E	A	E	V	Y	Q	A	I	H	H	Q	L	V	A	S	A	R	A
Query Conservation		.	.	.	.	.	.	.	.	.	.																							.	.
Alig confidence		.	.	.	.	.	.	.	.	.	.																							.	.																			.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																																																						.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		P	K	E	L	Y	S	E	E	A	V	N	G	E	T	Q	Q	A	H	L	Q	A	I	K	E	L	I	A	R	D	K	N	H	P	S	V	V	X	W	S	I	A	N	E	P	D	T	R	P	Q	G	A	R	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	E	Y	F	A	P	L
Template Known Secondary structure			S		S	S	B	T	T	T	B																				T	T		T	T														S	T				.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Predicted Secondary structure																																																						.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		371	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.																							.	.	.	.	.	.
		210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		V	K	A	C	H	S	L	L	P	E	A	K	I	G	N	M	L	L	G	G	L	V	Y	P	L	T	C	Q	P	Q	D	M	L	Q	A	M	E	E	N	R	R	W	M	F	F	G	D	V	Q	A	R	G	Q	Y	P	G	Y	M	Q	R	F	F	R	D	H	N	I	T	I	E	M	T	E	S	D	A	E	D	L	K
Query Conservation
Alig confidence																																	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																																	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		A	E	A	T	R	K	L	D	P	T	R	P	I	T	C	V	N	V	X	F	C	D	A	H	T	D	T	I	S	D	L	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Known Secondary structure										S	S	S						B		T	T	S		T	T	T		S	S	G	G	G	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Predicted Secondary structure																																	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		429	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.
		290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		H	T	V	D	F	I	S	F	S	Y	Y	M	T	G	C	V	S	H	D	E	S	I	N	K	N	A	Q	G	N	I	L	N	M	I	P	N	P	H	L	K	S	S	E	W	G	W	Q	I	D	P	V	G	L	R	V	L	L	N	T	L	W	D	R	Y	Q	K	P	L	F	I	V	E	N	G	L	G	A	K	D	S
Query Conservation
Alig confidence		.	.										.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation		.	.										.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		.	.	F	D	V	L	C	L	N	R	Y	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	Y	G	W	Y	V	Q	S	G	D	L	E	T	A	E	K	V	L	E	K	E	L	L	A	W	Q	E	K	L	H	Q	P	I	I	I	T	E	Y	G	V	D	T	L	A	G
Template Known Secondary structure		.	.	S	S	S							.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	B	T	T	T	B	S	T	T																																			T	T
Template Predicted Secondary structure		.	.										.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
				460	.	.	.	.	.	.	.	.																										.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.
		370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.				.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.
Predicted Secondary structure																																															.	.	.
Query SS confidence																																															.	.	.
Query Sequence		V	E	A	D	G	S	I	Q	D	D	Y	R	I	A	Y	L	N	D	H	L	V	Q	V	N	E	A	I	A	D	G	V	D	I	M	G	Y	T	S	W	G	P	I	D	L	V	.	.	.	S	A	S	H	S	Q	M	S	K	R	Y	G	F	I	Y	V	D	R	D	D	N	G	E	G	S	L	T	R	T	R	K	K
Query Conservation																																															.	.	.
Alig confidence														.	.																																.	.	.						.									.	.	.	.	.	.	.	.	.	.
Template Conservation														.	.																																								.									.	.	.	.	.	.	.	.	.	.
Template Sequence		L	H	S	X	Y	T	D	X	W	S	E	E	.	.	Y	Q	C	A	W	L	D	X	Y	H	R	V	F	D	R	V	S	A	V	V	G	E	Q	V	W	N	F	A	D	F	A	T	S	Q	G	I	L	R	V	.	G	G	N	K	K	G	I	F	.	.	.	.	.	.	.	.	.	.	T	R	D	R	K	P	K	S
Template Known Secondary structure					T	T			T	T	S			.	.														T	T		T	T							S					B		B			B	T	T	B	S	.	S	S	B						.	.	.	.	.	.	.	.	.	.		T	T			B		T
Template Predicted Secondary structure														.	.																																								.									.	.	.	.	.	.	.	.	.	.
Template SS confidence
		513	.	.	.	.	.	.	520	.	.	.	.			.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.		.	.	.	.	.	.	570	.											.	.	.	.	.	.	.	.
		447	.	.	450	.	.	.	.	.	.	.	.	.	460
Predicted Secondary structure
Query SS confidence
Query Sequence		S	F	G	W	Y	A	E	V	I	K	T	R	G	L
Query Conservation
Alig confidence
Template Conservation
Template Sequence		A	A	F	L	L	Q	K	R	W	T	G	X	N	F
Template Known Secondary structure													S		T
Template Predicted Secondary structure
Template SS confidence
		580	.	.	.	.	.	.	.	.	.	590	.	.	.

No model constructed - rank, confidence too low

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions