|   |
38 | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | |
|
|
|
. | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . |
Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |
|
|
|  |  | . | . | . | . |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
I | I | A | W | P | G | Y | I | E | R | G | Q | T | D | K | Q | Y | D | W | V | T | Q | F | E | K | E | T | G | C | A | V | N | V | K | T | A | A | T | S | D | . |
. |
. |
. |
E | M | V | S | L | M | T | K | G | G | Y | D | L | V | T | A | S | G | D | A | S | L | R | L | I | M | G | K | R | V | Q | P | I | N | T | A |
Query Conservation |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |   |
|
|   |
|   |   |   |   |   |   |   |   |   | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |
|   |   |   |
Alig confidence |   |
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|
|
|   | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |
|
|   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |
|   |   |   |
Template Sequence |   |
L | T | V | Y | V | . |
. |
. |
D | E | G | Y | K | S | Y | I | E | E | V | A | K | A | Y | E | K | E | A | G | V | K | V | T | L | K | T | G | D | A | L | G | G | L | D | K | L | S | L | D | N | Q | N | G | N | V | P | D | V | M | M | A | P | Y | D | R | V | G | S | L | G | S | D | G | Q | L | S | E | V | K | L | S |
Template Known Secondary structure |   |
|  |  |  |  | . | . | . |
| G | G | G |  |  |  |  |  |  |  |  |  |  |  |  |  |  | S | S |
|
|
|  |  |  |  |
|
|  |  |  |  |  |  | T |  |  |  |  |  |  |  | S |
|
|
| S |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
| B |
|
|
|
|
|
|
Template Predicted Secondary structure |   |
 |  |  |  |  | . | . | . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
43 | . | . | . | . | |
|
|
. | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . |
  |
  |   |
114 | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | |
|
|
|
|
. | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  | . | . | . | . | . |  |  |
|
|
|  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
Query Sequence |   |
L | I | P | N | W | K | T | L | D | P | R | V | V | K | G | D | W | F | N | V | G | G | K | V | Y | G | T | P | Y | Q | W | G | P | N | L | L | M | Y | N | T | K | T | F | P | T | P | P | D | S | W | Q | V | V | F | V | E | Q | N | L | P | D | G | K | S | N | K | G | R | V | . |
. |
. |
. |
. |
Q | A | Y | D | G | P |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . |   |   |
|
|   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
D | G | A | K | T | D | D | T | T | K | S | L | V | T | . |
. |
. |
. |
A | A | N | G | K | V | Y | G | A | P | A | V | I | E | S | L | V | M | Y | Y | N | K | D | L | V | K | D | A | P | K | T | F | A | D | L | E | N | L | A | K | D | S | K | Y | A | F | A | G | E | D | G | K | T | T | A | F | L | A | D | W | T | N |
Template Known Secondary structure |   |
G | G | G |
|
|
|  |  |  |  |  |  |  | B | . | . | . | . |
| T | T |
|
| B |
|
|  |  |  |  |  |  |
|
|  |  |  |  |  | T | T | T |
| S | S |
|
|
| B |  |  |  |  |  |  |  |  |  | S | G | G | G | B |
| T | T | S | T | T |
| B |
| S |  |  |
|
| T | T | S |
Template Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|  |  |  |  |  | . | . | . | . |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | |
|
|
|
. | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . |
  |
  |   |
189 | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | |
|
|
210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | |
|
|
|
. | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . | . | . | . |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
I | Y | I | A | D | A | A | L | F | V | K | A | T | Q | P | Q | L | G | I | S | D | . |
. |
. |
P | Y | Q | L | T | E | E | Q | Y | Q | A | V | L | K | V | L | R | A | Q | H | S | L | I | . |
. |
. |
. |
H | R | Y | W | H | D | T | T | V | Q | M | S | D | F | K | N | E | G | V | V | A | S | S | A | W | P | Y | Q | A |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |   | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |
Template Sequence |   |
F | Y | Y | T | Y | G | L | L | A | G | N | G | A | Y | V | F | G | Q | N | G | K | D | A | K | D | I | G | L | A | N | D | G | S | I | V | G | I | N | Y | A | K | S | W | Y | E | K | W | P | K | G | M | Q | D | T | E | G | A | G | N | L | I | Q | T | Q | F | Q | E | G | K | T | A | A | I | I | D | G | P | W | K | A |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |  |  | T |  |  |  |  |  |  | T | T | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | S |
| G | G | G | G |
| S | S |
|  |  |  |  |  |  |  |  |  |  | T | T |
|
| S |  |  |  |  |
| G | G | G |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
196 | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . |
  |
  |   |
262 | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
. | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
N | A | L | K | A | E | G | Q | P | V | A | T | V | F | P | K | E | . |
. |
. |
. |
. |
. |
. |
G | V | T | G | W | A | D | T | T | M | L | H | S | E | A | K | H | P | V | C | A | Y | K | W | M | N | W | S | L | T | P | K | V | Q | G | D | V | A | A | W | F | G | S | L | P | V | V | P | E | G | C | K | A | S | P | L |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   | . | . | . | . | . | . | . |
|   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|   |   |   |
|
|   |   |
|
|   |   |
|   |
|   |
|   |
|   |   |   |
|   |   |   |
|   |   |
|   |   |   |   |
|   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |
|   |   |
|
|   |   |
|   |
|   |
|   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
Q | A | F | K | D | A | K | V | N | Y | G | V | A | T | I | P | T | L | P | N | G | K | E | Y | A | A | F | G | G | G | K | A | W | V | I | P | Q | A | V | K | N | L | E | A | S | Q | K | F | V | D | F | L | V | A | T | E | Q | Q | K | V | L | Y | D | K | T | N | E | I | P | A | N | T | E | A | R | S | Y | A | E | G |
Template Known Secondary structure |   |
 |  |  |  |  | T | T |
|
|  |  |  |  |
|
|
| B |
| T | T | S |
|
|
|
|
|  |  |  |  |  |  |  |  |
| B | T | T |
| S |
|  |  |  |  |  |  |  |  |  |  |  |  | S |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  | S | S |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
276 | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . |
  |
  |   |
335 | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | G | E | K | G | C | E | T | N | G | F | N | Y | F | D | K | I | A | F | W | K | T | P | I | A | E | G | G | K | F | V | P | Y | S | R | W | T | Q | D | Y | I | A | I | M | G | G | R |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
Template Sequence |   |
K | N | D | E | L | T | T | A | . |
. |
. |
. |
V | I | K | Q | F | K | N | T | Q | P | L | P | N | I | S | Q | M | S | A | V | W | D | P | A | K | N | M | L | F | D | A | V | S | G | Q |
Template Known Secondary structure |   |
 |
|
|  |  |  |  |  | . | . | . | . |  |  |  |  |  |  | S |
|  |  |
|
|
| S | G | G | G | G | G | T |  |  |  |  |  |  |  |  |  |  |  |  | T | T | S |
Template Predicted Secondary structure |   |
 |
|
|  |  |  |  |  | . | . | . | . |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
356 | . | . | . | 360 | . | . | . | |
|
|
|
. | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . |
  |