|   |
1058 | . | 1060 | . | . | . | . | . | . | . | . | . | 1070 | . | . | . | . | . | . | . | . | . | 1080 | . | . | . | . | . | . | . | . | . | 1090 | . | |
|
|
|
|
|
|
. | . | . | . | . | . | . | . | 1100 | . | . | . | . | . | . | . | . | . | 1110 | |
|
|
|
. | . | . | . | . | . | . | . | . | 1120 | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
| . | . | . | . | . | . | . |
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | P | L | R | E | G | N | G | P | T | L | F | C | F | H | P | A | S | G | F | A | W | Q | F | S | V | L | S | R | Y | L | D | P | Q | . |
. |
. |
. |
. |
. |
. |
W | S | I | I | G | I | Q | S | P | R | P | N | G | P | M | Q | T | A | A | . |
. |
. |
. |
N | L | D | E | V | C | E | A | H | L | A | T | L | L | E | Q |
Query Conservation |   |
  |   |   |   |   |
|   |   |   |   |
|
|   |   |
|   |   |   |
|   |   |   |   |
|   |   |
|   |   |   |
|   |   |   | . | . | . | . | . | . | . |   |   |
|
|
|
|   |   |
|   |   |   |   |   |   |   |   |   |   | . | . | . | . |   |
|   |   |   |
|   |   |
|   |   |   |
|   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |
|
|
|
|
|
|
|   |
|   |
|   |   |   |   |   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|
|
|
|
|
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |
|
|   |   |
|
Template Sequence |   |
L | F | S | E | R | E | D | A | V | P | I | A | L | L | H | G | W | P | G | S | F | V | E | F | Y | P | I | L | Q | L | F | R | E | E | Y | T | P | E | T | L | P | F | H | L | V | V | P | S | L | P | G | Y | T | F | S | S | G | P | P | L | D | K | D | F | G | L | M | D | N | A | R | V | V | D | Q | L | M | K | D | L |
Template Known Secondary structure |   |
 |
|
| S |
| T | T |
|  |  |  |  |  |  |
|
| S | S |
|
| G | G | G | G |  |  |  |  |  |  |  |  |  |  |
|
| T | T | T |
|
|  |  |  |  |  |  |
|
| T | T | S | T | T | S |
|
|
|
| S | S | S |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
Template Predicted Secondary structure |   |
 |
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
101 | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 |
  |
  |   |
1127 | . | . | 1130 | . | . | . | . | . | . | . | . | . | 1140 | . | . | . | . | . | . | . | . | . | 1150 | . | . | . | . | . | . | . | . | . | 1160 | . | . | . | . | . | . | . | . | . | 1170 | . | . | . | . | . | . | . | . | . | 1180 | . | . | . | . | . | . | . | . | . | 1190 | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Sequence |   |
Q | P | H | G | P | Y | Y | L | L | G | Y | S | L | G | G | T | L | A | Q | G | I | A | A | R | L | R | A | R | G | E | Q | V | A | F | L | G | L | L | D | T | W | P | P | E | T | Q | N | W | Q | E | K | E | A | N | G | L | D | P | E | V | L | A | E | I | N | R | E | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Conservation |   |
  |
|   |
|
|
|   |
|   |
|   |
|   |
|
|   |
|
|   |
|   |
|   |   |
|   |   |   |
|   |   |
|   |   |
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
  |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |   |   |
|   |   |   | . | . | . | . |
|   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
G | F | G | S | G | Y | I | I | Q | G | G | D | I | G | S | F | V | G | R | L | L | G | V | G | F | . |
. |
. |
. |
D | A | C | K | A | V | H | L | N | L | C | A | M | R | A | P | P | E | G | P | S | I | E | S | L | S | A | A | E | K | E | G | I | A | R | M | E | K | F | M | T | D | G | L | A | Y | A | M | E | H | S |
Template Known Secondary structure |   |
T |
| T | T |
|  |  |  |  |  |
| T |  |  |  |  |  |  |  |  |  |  |  |  |
| . | . | . | . | T | T |  |  |  |  |  |  | S |
|
|
|
|
| S |
| S | S | S |
|
| G | G | G | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | S |
|  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|  |  |  |
|
|
| . | . | . | . |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
181 | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | |
|
|
|
. | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . |
  |
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
1194 | . | . | . | . | . | 1200 | . | . | . | . | . | . | . | . | . | 1210 | . | . | . | . | . | . | . | . | . | 1220 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
. | . | . | 1230 | . | . | . | . | . | . | . | . | . | 1240 | . |
Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
Query SS confidence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
R | E | A | F | L | A | A | Q | Q | G | S | T | S | T | E | L | F | T | T | I | E | G | N | Y | A | D | A | V | R | L | L | T | T | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
A | H | S | V | P | F | D | G | K | A | T | L | F | V | A |
Query Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |   |   |   |   |   |
|   |   |
|
|   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|   |
|
|
|   |
|
Template Sequence |   |
T | R | P | S | T | I | G | H | V | L | S | S | S | P | I | A | L | L | A | W | I | G | E | K | Y | L | Q | W | V | D | K | P | L | P | S | E | T | I | L | E | M | V | S | L | Y | W | L | T | E | S | F | P | R | A | I | H | T | Y | R | E | T | T | P | M | L | Q | K | E | L | Y | I | H | K | P | F | G | F | S | F | F |
Template Known Secondary structure |   |
 |
|  |  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | S |
| S | S |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  | G | G | G |  |  |  |  |
|
|
| T | T | T | T | T |
|  |  |  |  |  |  |  |  |  |
|
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
257 | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . |
  |
  |   |
1242 | . | . | . | . | . | . | . | 1250 | . | . | . | . | . | . | . | . | . | 1260 | . | |
. | . | . | . | . | . | . | |
. | 1270 | . | . | . | . | . | . | . | . | . | 1280 | . | . | . | . | . | . | . | . | . | 1290 | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
| . |
|  |  |  |  |  |
| . |
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | R | T | L | Q | E | G | M | S | P | E | R | A | W | S | P | W | I | A | E | . |
L | D | I | Y | R | Q | D | . |
C | A | H | V | D | I | I | S | P | G | T | F | E | K | I | G | P | I | I | R | A | T | L | N | R |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   | . |   |   |   |   |   |
|   | . |
|   |
|   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|   |
|
Alig confidence |   |
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |   |   |   |   | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |   |
|   |
| . | . |
|   |   |
|   |   |
|   |   |
|
|   |   |
Template Sequence |   |
P | K | D | L | C | P | V | P | . |
. |
. |
R | S | W | I | A | T | T | G | N | L | V | F | F | R | D | H | A | E | G | G | H | F | A | A | L | E | R | P | . |
. |
R | E | L | K | T | D | L | T | A | F | V | E | Q |
Template Known Secondary structure |   |
T | B | S | S | S |
|
|
| . | . | . |  |  |  |  | G | G | G |  |  |  |  |  |  |  |  |
| S | S |
| B | S |
|  |  |  |  |
|  | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|  | . | . | . |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|  | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
346 | . | . | . | 350 | . | . | . | |
|
|
. | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | |
|
. | . | . | . | . | . | . | . | 390 | . | . | . | . |
  |