Job Description P11454 Confidence 100.00% Date Thu Jan 5 11:32:39 GMT 2012 Rank 15 Aligned Residues 482 % Identity 21% Template c3eynB_ PDB info PDB header:ligase Chain: B: PDB Molecule:acyl-coenzyme a synthetase acsm2a; PDBTitle: crystal structure of human acyl-coa synthetase medium-chain2 family member 2a (l64p mutation) in a complex with coa Resolution 1.90 Å

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		458	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.						.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.		.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.
Predicted Secondary structure																							.	.	.	.	.																					.
Query SS confidence																							.	.	.	.	.																					.
Query Sequence		S	A	L	V	A	E	Q	A	A	K	T	P	D	A	P	A	L	A	D	A	R	.	.	.	.	.	Y	L	F	S	Y	R	E	M	R	E	Q	V	V	A	L	A	N	L	L	R	.	E	R	G	V	K	P	G	D	S	V	A	V	A	L	P	R	S	V	F	L	T	L	A	L	H	A	I	V	E	A	G	A	A
Query Conservation																							.	.	.	.	.																					.
Alig confidence																							.	.	.	.	.																					.
Template Conservation
Template Sequence		H	W	A	D	M	E	K	A	G	K	R	P	P	S	P	A	L	W	W	V	N	G	K	G	K	E	L	M	W	N	F	R	E	L	S	E	N	S	Q	Q	A	A	N	V	L	S	G	A	C	G	L	Q	R	G	D	R	V	A	V	V	L	P	R	V	P	E	W	W	L	V	I	L	G	C	I	R	A	G	L	I
Template Known Secondary structure									T	T	S	S											S	S	S																							T	T	T				T	T									S														T	T
Template Predicted Secondary structure
Template SS confidence
		53	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.
		532	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.															.	.	.	.	590	.	.	.	.	.	.	.
Predicted Secondary structure																																																								.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence																																																								.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		W	L	P	L	D	T	G	Y	P	D	D	R	L	K	M	M	L	E	D	A	R	P	S	L	L	I	T	T	D	D	Q	L	P	R	F	S	D	V	P	N	L	T	S	L	C	Y	N	A	P	L	T	P	Q	G	.	.	.	.	.	.	.	.	.	.	.	.	.	.	S	A	P	L	Q	L	S	Q	P	H	H	T
Query Conservation																																																								.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence																																																								.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		F	M	P	G	T	I	Q	M	K	S	T	D	I	L	Y	R	L	Q	M	S	K	A	K	A	I	V	A	G	D	E	V	I	Q	E	V	D	T	V	A	S	E	C	P	S	L	R	I	K	L	L	V	S	E	K	S	C	D	G	W	L	N	F	K	K	L	L	N	E	A	S	T	T	H	H	C	V	E	T	G	S
Template Known Secondary structure							T	T														T		S						T	T	T								G	G	G		T	T								S	S	S			T	T											S		S								B	T
Template Predicted Secondary structure
Template SS confidence
		133	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.
		598	.	600	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.	.	.	.	.	.	.	.	.	660	.	.	.	.	.	.	.	.	.	670	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		A	Y	I	I	F	T	S	G	S	T	G	R	P	K	G	V	M	V	G	Q	T	A	I	V	N	R	L	L	W	M	Q	N	H	Y	P	L	T	G	E	D	V	V	A	Q	K	T	P	C	S	F	D	V	S	V	W	E	F	F	W	P	F	I	A	G	A	K	L	V	M	A	E	P	E	A	H	R	D	P	L	A
Query Conservation
Alig confidence
Template Conservation
Template Sequence		Q	E	A	S	A	I	Y	F	T	S	G	L	P	K	M	A	E	H	S	Y	S	S	L	G	L	K	A	K	M	D	A	G	W	T	G	L	Q	A	S	D	I	M	W	T	I	S	D	T	G	W	I	L	N	I	L	C	S	L	M	E	P	W	A	L	G	A	C	T	F	V	H	L	L	P	K	F	D	P	L	V
Template Known Secondary structure		T	S																													T	T	T	T	S			T	T									T	T	S							T	T							T									S	S
Template Predicted Secondary structure
Template SS confidence
		213	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.
		678	.	680	.	.	.	.	.	.	.	.	.	690	.	.	.	.	.	.	.	.	.	700	.	.	.	.	.	.	.	.	.	710	.	.	.	.	.	.	.	.	.	720	.	.	.	.	.	.	.	.	.	730	.	.	.	.	.	.	.	.	.	740	.	.	.	.	.	.	.	.	.	750	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		M	Q	Q	F	F	A	E	Y	G	V	T	T	T	H	F	V	P	S	M	L	A	A	F	V	A	S	L	T	P	Q	T	A	R	Q	S	C	A	T	L	K	Q	V	F	C	S	G	E	A	L	P	A	D	L	C	R	E	W	Q	Q	L	T	G	A	P	L	H	N	L	Y	G	P	T	E	A	A	V	D	V	S	W
Query Conservation
Alig confidence																														.	.	.
Template Conservation																														.	.	.
Template Sequence		I	L	K	T	L	S	S	Y	P	I	K	S	M	M	G	A	P	I	V	Y	R	M	L	L	Q	Q	D	L	.	.	.	S	S	Y	K	F	P	H	L	Q	N	C	V	T	V	G	E	S	L	L	P	E	T	L	E	N	W	R	A	Q	T	G	L	D	I	R	E	S	Y	G	Q	T	E	T	G	L	T	C	M	V
Template Known Secondary structure									S																	T	S		T	.	.	.	T	S	S			T	T								S	S															S										T	T	T
Template Predicted Secondary structure																														.	.	.
Template SS confidence
		296	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.				.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.
		758	.	760	.	.	.	.	.	.	.	.	.	770	.	.	.	.	.	.	.	.	.	780	.	.	.	.	.	.	.	.	.	790	.	.	.	.	.	.	.	.	.	800	.	.	.	.	.	.	.						.	.	810	.	.	.	.	.	.	.	.	.	820	.	.	.	.	.	.	.	.	.	830	.	.
Predicted Secondary structure																																																				.	.	.	.	.
Query SS confidence																																																				.	.	.	.	.
Query Sequence		Y	P	A	F	G	E	E	L	A	Q	V	R	G	S	S	V	P	I	G	Y	P	V	W	N	T	G	L	R	I	L	D	A	M	M	H	P	V	P	P	G	V	A	G	D	L	Y	L	T	G	I	.	.	.	.	.	Q	L	A	Q	G	Y	L	G	R	P	D	L	T	A	S	R	F	I	A	D	P	F	A	P	G
Query Conservation																																																				.	.	.	.	.
Alig confidence											.	.	.	.	.	.	.																																			.	.	.	.	.																				.	.	.	.	.	.
Template Conservation											.	.	.	.	.	.	.																																																											.	.	.	.	.	.
Template Sequence		S	K	T	M	K	I	K	P	G	.	.	.	.	.	.	.	Y	M	G	T	A	A	S	C	Y	D	V	Q	I	I	D	D	K	G	N	V	L	P	P	G	T	E	G	D	I	G	I	R	V	K	P	I	R	P	I	G	I	F	S	G	Y	V	D	N	P	D	K	T	A	A	N	I	R	G	.	.	.	.	.	.
Template Known Secondary structure			T	T	S				T	T	.	.	.	.	.	.	.							T	T								T	T	S		B			T	T										S	S	B			T	T	S					T	T								T			T	.	.	.	.	.	.
Template Predicted Secondary structure											.	.	.	.	.	.	.																																																											.	.	.	.	.	.
Template SS confidence
		373	.	.	.	.	.	.	380	.								.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.
		833	.	.	.	.	.	.	840	.	.	.	.	.	.	.	.	.	850	.	.	.	.	.	.	.	.	.	860	.	.	.	.	.	.	.	.	.	870	.	.	.	.	.	.	.	.	.	880	.	.	.	.	.	.	.	.	.	890	.	.	.	.	.	.	.	.	.	900	.	.	.	.	.	.	.	.	.	910	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		E	R	M	Y	R	T	G	D	V	A	R	W	L	D	N	G	A	V	E	Y	L	G	R	S	D	D	Q	L	K	I	R	G	Q	R	I	E	L	G	E	I	D	R	V	M	Q	A	L	P	D	V	E	Q	A	V	T	H	A	C	V	I	N	Q	A	A	A	T	G	G	D	A	R	Q	L	V	G	Y	L	V	S	Q
Query Conservation
Alig confidence		.																																																																.	.	.	.	.	.
Template Conservation		.																																																																.	.	.	.	.	.
Template Sequence		.	D	F	W	L	L	G	D	R	G	I	K	D	E	D	G	Y	F	Q	F	M	G	R	A	D	D	I	I	N	S	S	G	Y	R	I	G	P	S	E	V	E	N	A	L	M	E	H	P	A	V	V	E	T	A	V	I	S	S	P	D	P	V	R	G	.	.	.	.	.	.	E	V	V	K	A	F	V	V	L	A
Template Known Secondary structure		.	T												T	T	S								G	G	G					T	T														T	S	T	T												T	T	T		.	.	.	.	.	.
Template Predicted Secondary structure		.																																																																.	.	.	.	.	.
Template SS confidence
			440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.							.	.	.	.	.	.	.	510	.	.
		913						.	.	.	.	.	.	920	.	.	.	.	.	.	.	.	.	930	.	.	.	.	.	.	.	.	.	940	.	.	.	.	.	.	.	.	.	950	.	.	.	.	.	.	.	.	.	960	.	.
Predicted Secondary structure			.	.	.	.	.
Query SS confidence			.	.	.	.	.
Query Sequence		S	.	.	.	.	.	G	L	P	L	D	T	S	A	L	Q	A	Q	L	R	E	T	L	P	P	H	M	V	P	V	V	L	L	Q	L	P	Q	L	P	L	S	A	N	G	K	L	D	R	K	A	L	P	L	P	E
Query Conservation			.	.	.	.	.
Alig confidence			.	.	.	.	.
Template Conservation
Template Sequence		S	Q	F	L	S	H	D	P	E	Q	L	T	K	E	L	Q	Q	H	V	K	S	V	T	A	P	Y	K	Y	P	R	K	I	E	F	V	L	N	L	P	K	T	V	T	G	K	I	Q	R	A	K	L	R	D	K	E
Template Known Secondary structure		G	G	G	G	G	S																	S		G	G	G	S		S						S				B		T	T			B
Template Predicted Secondary structure
Template SS confidence
		513	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.