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Job DescriptionP11454
Confidence99.94%DateThu Jan 5 11:32:39 GMT 2012
Rank49Aligned Residues229
% Identity20%Templatec2px6A_
PDB info PDB header:transferaseChain: A: PDB Molecule:thioesterase domain; PDBTitle: crystal structure of the thioesterase domain of human fatty2 acid synthase inhibited by orlistat
Resolution2.30 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   1051........1060. ........1070.........1080.........1090.........1100.........1110.........1120........
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Query Sequence  RMGFETILPLR. . EGNGPTLFCFHPASGFAWQFSVLSRYLDPQWSIIGIQSPRPNGPMQTAANLDEVCEAHLATLLEQQP
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Template Sequence  NPEGPTLMRLNSVQSSERPLFLVHPIEGSTTVFHSLASRL. . SIPTYGLQCTRAAPLD. . . . SIHSLAAYYIDCIRQVQP
Template Known Secondary structure 
TTS
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SS



TT

SGGG
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TT....
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S
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   2225....2230.........2240.........2250.........2260.... .....2270.........2280 .........2290........
 
   11291130.........1140.........1150.........1160.........1170 .........1180.........1190..
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Query Sequence  HGPYYLLGYSLGGTLAQGIAARLRARGEQVAFLGLLDTWPPE. . . . . . . . . . . . . . . . TQNWQEKEANGLDPEVLAEINR
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Template Sequence  EGPYRVAGYSYGACVAFEMCSQLQAQQPTHNSLFLFDGSPTYAEAETEAICFFVQQFTDMEHNRVLEALLPLKGLEERVA
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S
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   22992300.........2310.........2320.........2330.........2340.........2350.........2360.........2370........
 
   1193......1200.........1210.........1220.........1230 .........1240.........1250......... 1260.........1270
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Query Sequence  EREAFLAAQQGSTSTELFTTIEGNYADAVRLLTTAHSV. PFDGKATLFVAERTLQEGMSPERAWSPWI. AELDIYRQDCA
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Template Sequence  AAVDLIIKSHQGLDRQELSFAARSFYYKLRAAEQYTPKAKYHGNVMLLRAKTGA. . . . . . DYNLSQVCDGKVSVHVIEGD
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T



S
B
S



T......TTTTTTTB
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   23992400.........2410.........2420.........2430.........2440.........2450.. .......2460.........2470..
 
   1271........1280.........1290.
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Query Sequence  HVDIISPGTFEKIGPIIRATL
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Template Sequence  HRTLLEGSGLESIISIIHSSL
Template Known Secondary structure  TTGGGS
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   2481........2490.........2500.
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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