Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	A	N	H	E	T	H	S	V	I	A	G	G	I	E	S	D	L	H	I	D	S	S	K	Y	P	H	P	F	C	S	L	L	Q	K	R	A	H	F	D	S	F	K	H	L	I	F	I	R	G	L	L	V	I	A	H	G	K	R	K
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?																																																			?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.
Sequence		N	K	I	S	A	S	M	V	S	F	Y	V	S	L	V	Q	V	M	C	A	H	Y	I	P	D	T	N	K	V	N	L
Secondary structure
SS confidence
Disorder		?		?																							?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2jp3 chain A Region: 41 - 64 Aligned: 24 Modelled: 24 Confidence: 12.1% Identity: 29% PDB header:transcription Chain: A: PDB Molecule:fxyd domain-containing ion transport regulator 4; PDBTitle: solution structure of the human fxyd4 (chif) protein in sds2 micelles Phyre2 PDB 1tjn chain A Region: 49 - 74 Aligned: 26 Modelled: 26 Confidence: 11.2% Identity: 27% PDB header:lyase Chain: A: PDB Molecule:sirohydrochlorin cobaltochelatase; PDBTitle: crystal structure of hypothetical protein af0721 from archaeoglobus2 fulgidus Phyre2 PDB 1tjn chain A Region: 49 - 74 Aligned: 26 Modelled: 26 Confidence: 11.2% Identity: 27% Fold: Chelatase-like Superfamily: Chelatase Family: CbiX-like Phyre2 PDB 1i0v chain A Region: 15 - 29 Aligned: 15 Modelled: 15 Confidence: 9.5% Identity: 33% Fold: Microbial ribonucleases Superfamily: Microbial ribonucleases Family: Fungal ribonucleases Phyre2 PDB 2drp chain A domain 2 Region: 25 - 30 Aligned: 6 Modelled: 6 Confidence: 8.9% Identity: 83% Fold: beta-beta-alpha zinc fingers Superfamily: beta-beta-alpha zinc fingers Family: Classic zinc finger, C2H2 Phyre2 PDB 3a9l chain B Region: 16 - 39 Aligned: 24 Modelled: 24 Confidence: 8.3% Identity: 21% PDB header:hydrolase Chain: B: PDB Molecule:poly-gamma-glutamate hydrolase; PDBTitle: structure of bacteriophage poly-gamma-glutamate hydrolase Phyre2 PDB 2crg chain A domain 1 Region: 44 - 68 Aligned: 23 Modelled: 25 Confidence: 7.5% Identity: 26% Fold: DNA/RNA-binding 3-helical bundle Superfamily: Homeodomain-like Family: Myb/SANT domain Phyre2 PDB 2jo1 chain A Region: 41 - 62 Aligned: 22 Modelled: 22 Confidence: 7.3% Identity: 23% PDB header:hydrolase regulator Chain: A: PDB Molecule:phospholemman; PDBTitle: structure of the na,k-atpase regulatory protein fxyd1 in2 micelles Phyre2 PDB 2kaa chain A Region: 18 - 29 Aligned: 12 Modelled: 12 Confidence: 6.2% Identity: 33% PDB header:toxin Chain: A: PDB Molecule:hirsutellin a; PDBTitle: solution structure of hirsutellin a from hirsutella2 thompsonii Phyre2 PDB 2oqb chain A Region: 26 - 34 Aligned: 9 Modelled: 9 Confidence: 6.2% Identity: 56% PDB header:transferase,gene regulation Chain: A: PDB Molecule:histone-arginine methyltransferase carm1; PDBTitle: crystal structure of the n-terminal domain of coactivator-associated2 methyltransferase 1 (carm1) Phyre2 PDB 1isu chain A Region: 78 - 87 Aligned: 10 Modelled: 10 Confidence: 5.9% Identity: 30% Fold: HIPIP (high potential iron protein) Superfamily: HIPIP (high potential iron protein) Family: HIPIP (high potential iron protein) Phyre2 PDB 3kdp chain G Region: 42 - 54 Aligned: 13 Modelled: 13 Confidence: 5.7% Identity: 46% PDB header:hydrolase Chain: G: PDB Molecule:na+/k+ atpase gamma subunit transcript variant a; PDBTitle: crystal structure of the sodium-potassium pump Phyre2 PDB 3kdp chain H Region: 42 - 54 Aligned: 13 Modelled: 13 Confidence: 5.7% Identity: 46% PDB header:hydrolase Chain: H: PDB Molecule:na+/k+ atpase gamma subunit transcript variant a; PDBTitle: crystal structure of the sodium-potassium pump Phyre2 PDB 3m8e chain A Region: 60 - 86 Aligned: 20 Modelled: 27 Confidence: 5.7% Identity: 50% PDB header:dna binding protein Chain: A: PDB Molecule:putative dna-binding protein; PDBTitle: protein structure of type iii plasmid segregation tubr Phyre2 1 c2jp3A_ 2 c1tjnA_ 3 d1tjna_ 4 d1i0va_ 5 d2drpa2 6 c3a9lB_ 7 d2crga1 8 c2jo1A_ 9 c2kaaA_ 10 c2oqbA_ 11 d1isua_ 12 c3kdpG_ 13 c3kdpH_ 14 c3m8eA_

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c2jp3A_ 12.1 29 PDB header:transcription Chain: A: PDB Molecule:fxyd domain-containing ion transport regulator 4; PDBTitle: solution structure of the human fxyd4 (chif) protein in sds2 micelles 2 c1tjnA_ 11.2 27 PDB header:lyase Chain: A: PDB Molecule:sirohydrochlorin cobaltochelatase; PDBTitle: crystal structure of hypothetical protein af0721 from archaeoglobus2 fulgidus 3 d1tjna_ 11.2 27 Fold:Chelatase-like Superfamily:Chelatase Family:CbiX-like 4 d1i0va_ 9.5 33 Fold:Microbial ribonucleases Superfamily:Microbial ribonucleases Family:Fungal ribonucleases 5 d2drpa2 8.9 83 Fold:beta-beta-alpha zinc fingers Superfamily:beta-beta-alpha zinc fingers Family:Classic zinc finger, C2H2 6 c3a9lB_ 8.3 21 PDB header:hydrolase Chain: B: PDB Molecule:poly-gamma-glutamate hydrolase; PDBTitle: structure of bacteriophage poly-gamma-glutamate hydrolase 7 d2crga1 7.5 26 Fold:DNA/RNA-binding 3-helical bundle Superfamily:Homeodomain-like Family:Myb/SANT domain 8 c2jo1A_ 7.3 23 PDB header:hydrolase regulator Chain: A: PDB Molecule:phospholemman; PDBTitle: structure of the na,k-atpase regulatory protein fxyd1 in2 micelles 9 c2kaaA_ 6.2 33 PDB header:toxin Chain: A: PDB Molecule:hirsutellin a; PDBTitle: solution structure of hirsutellin a from hirsutella2 thompsonii 10 c2oqbA_ 6.2 56 PDB header:transferase,gene regulation Chain: A: PDB Molecule:histone-arginine methyltransferase carm1; PDBTitle: crystal structure of the n-terminal domain of coactivator-associated2 methyltransferase 1 (carm1) 11 d1isua_ 5.9 30 Fold:HIPIP (high potential iron protein) Superfamily:HIPIP (high potential iron protein) Family:HIPIP (high potential iron protein) 12 c3kdpG_ 5.7 46 PDB header:hydrolase Chain: G: PDB Molecule:na+/k+ atpase gamma subunit transcript variant a; PDBTitle: crystal structure of the sodium-potassium pump 13 c3kdpH_ 5.7 46 PDB header:hydrolase Chain: H: PDB Molecule:na+/k+ atpase gamma subunit transcript variant a; PDBTitle: crystal structure of the sodium-potassium pump 14 c3m8eA_ 5.7 50 PDB header:dna binding protein Chain: A: PDB Molecule:putative dna-binding protein; PDBTitle: protein structure of type iii plasmid segregation tubr

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0