Phyre 2 Results for P13960

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Email | l.a.kelley@imperial.ac.uk
Description | P13960
Date | Thu Jan 5 11:33:48 GMT 2012
Unique Job ID | 19e7ab72537cd9cd

Summary |

Top model
Image coloured by rainbow N → C terminus
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Model (left) based on template c2jp3A_
Top template information
PDB header:transcription Chain: A: PDB Molecule:fxyd domain-containing ion transport regulator 4; PDBTitle: solution structure of the human fxyd4 (chif) protein in sds2 micelles
Confidence and coverage
Confidence: | 12.1% | Coverage: | 26%
24 residues ( 26% of your sequence) have been modelled with 12.1% confidence by the single highest scoring template.
You may wish to submit your sequence to Phyrealarm. This will automatically scan your sequence every week for new potential templates as they appear in the Phyre2 library.
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Sequence analysis |

Secondary structure and disorder prediction |

|  | 1 | . | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60
Sequence |  | M | A | N | H | E | T | H | S | V | I | A | G | G | I | E | S | D | L | H | I | D | S | S | K | Y | P | H | P | F | C | S | L | L | Q | K | R | A | H | F | D | S | F | K | H | L | I | F | I | R | G | L | L | V | I | A | H | G | K | R | K
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? | ? | ? | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | .
Sequence |  | N | K | I | S | A | S | M | V | S | F | Y | V | S | L | V | Q | V | M | C | A | H | Y | I | P | D | T | N | K | V | N | L
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? |  | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? | ? | ? | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |

Confidence Key
High(9) |  |  |  |  |  |  |  |  |  |  | Low (0)

? | Disordered
| Alpha helix
| Beta strand

Domain analysis |

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank | Aligned region
--- | ---
1 |
| c2jp3A_ |

### PDB 2jp3 chain A

Region: 41 - 64
Aligned: 24
Modelled: 24
Confidence: 12.1%
Identity: 29%
PDB header:transcription
Chain: A: PDB Molecule:fxyd domain-containing ion transport regulator 4;
PDBTitle: solution structure of the human fxyd4 (chif) protein in sds2 micelles

Phyre2
2 |
| c1tjnA_ |

### PDB 1tjn chain A

Region: 49 - 74
Aligned: 26
Modelled: 26
Confidence: 11.2%
Identity: 27%
PDB header:lyase
Chain: A: PDB Molecule:sirohydrochlorin cobaltochelatase;
PDBTitle: crystal structure of hypothetical protein af0721 from archaeoglobus2 fulgidus

Phyre2
3 |
| d1tjna_ |

### PDB 1tjn chain A

Region: 49 - 74
Aligned: 26
Modelled: 26
Confidence: 11.2%
Identity: 27%
Fold: Chelatase-like
Superfamily: Chelatase
Family: CbiX-like

Phyre2
4 |
| d1i0va_ |

### PDB 1i0v chain A

Region: 15 - 29
Aligned: 15
Modelled: 15
Confidence: 9.5%
Identity: 33%
Fold: Microbial ribonucleases
Superfamily: Microbial ribonucleases
Family: Fungal ribonucleases

Phyre2
5 |
| d2drpa2 |

### PDB 2drp chain A domain 2

Region: 25 - 30
Aligned: 6
Modelled: 6
Confidence: 8.9%
Identity: 83%
Fold: beta-beta-alpha zinc fingers
Superfamily: beta-beta-alpha zinc fingers
Family: Classic zinc finger, C2H2

Phyre2
6 |
| c3a9lB_ |

### PDB 3a9l chain B

Region: 16 - 39
Aligned: 24
Modelled: 24
Confidence: 8.3%
Identity: 21%
PDB header:hydrolase
Chain: B: PDB Molecule:poly-gamma-glutamate hydrolase;
PDBTitle: structure of bacteriophage poly-gamma-glutamate hydrolase

Phyre2
7 |
| d2crga1 |

### PDB 2crg chain A domain 1

Region: 44 - 68
Aligned: 23
Modelled: 25
Confidence: 7.5%
Identity: 26%
Fold: DNA/RNA-binding 3-helical bundle
Superfamily: Homeodomain-like
Family: Myb/SANT domain

Phyre2
8 |
| c2jo1A_ |

### PDB 2jo1 chain A

Region: 41 - 62
Aligned: 22
Modelled: 22
Confidence: 7.3%
Identity: 23%
PDB header:hydrolase regulator
Chain: A: PDB Molecule:phospholemman;
PDBTitle: structure of the na,k-atpase regulatory protein fxyd1 in2 micelles

Phyre2
9 |
| c2kaaA_ |

### PDB 2kaa chain A

Region: 18 - 29
Aligned: 12
Modelled: 12
Confidence: 6.2%
Identity: 33%
PDB header:toxin
Chain: A: PDB Molecule:hirsutellin a;
PDBTitle: solution structure of hirsutellin a from hirsutella2 thompsonii

Phyre2
10 |
| c2oqbA_ |

### PDB 2oqb chain A

Region: 26 - 34
Aligned: 9
Modelled: 9
Confidence: 6.2%
Identity: 56%
PDB header:transferase,gene regulation
Chain: A: PDB Molecule:histone-arginine methyltransferase carm1;
PDBTitle: crystal structure of the n-terminal domain of coactivator-associated2 methyltransferase 1 (carm1)

Phyre2
11 |
| d1isua_ |

### PDB 1isu chain A

Region: 78 - 87
Aligned: 10
Modelled: 10
Confidence: 5.9%
Identity: 30%
Fold: HIPIP (high potential iron protein)
Superfamily: HIPIP (high potential iron protein)
Family: HIPIP (high potential iron protein)

Phyre2
12 |
| c3kdpG_ |

### PDB 3kdp chain G

Region: 42 - 54
Aligned: 13
Modelled: 13
Confidence: 5.7%
Identity: 46%
PDB header:hydrolase
Chain: G: PDB Molecule:na+/k+ atpase gamma subunit transcript variant a;
PDBTitle: crystal structure of the sodium-potassium pump

Phyre2
13 |
| c3kdpH_ |

### PDB 3kdp chain H

Region: 42 - 54
Aligned: 13
Modelled: 13
Confidence: 5.7%
Identity: 46%
PDB header:hydrolase
Chain: H: PDB Molecule:na+/k+ atpase gamma subunit transcript variant a;
PDBTitle: crystal structure of the sodium-potassium pump

Phyre2
14 |
| c3m8eA_ |

### PDB 3m8e chain A

Region: 60 - 86
Aligned: 20
Modelled: 27
Confidence: 5.7%
Identity: 50%
PDB header:dna binding protein
Chain: A: PDB Molecule:putative dna-binding protein;
PDBTitle: protein structure of type iii plasmid segregation tubr

Phyre2

Detailed template information |

# | Template | Alignment Coverage | 3D Model | Confidence | % i.d. | Template Information
--- | --- | --- | --- | --- | --- | ---
1 | c2jp3A_ |
|  | 12.1 | 29 | PDB header:transcription Chain: A: PDB Molecule:fxyd domain-containing ion transport regulator 4; PDBTitle: solution structure of the human fxyd4 (chif) protein in sds2 micelles
2 | c1tjnA_ |
|  | 11.2 | 27 | PDB header:lyase Chain: A: PDB Molecule:sirohydrochlorin cobaltochelatase; PDBTitle: crystal structure of hypothetical protein af0721 from archaeoglobus2 fulgidus
3 | d1tjna_ |
|  | 11.2 | 27 | Fold:Chelatase-like Superfamily:Chelatase Family:CbiX-like
4 | d1i0va_ |
|  | 9.5 | 33 | Fold:Microbial ribonucleases Superfamily:Microbial ribonucleases Family:Fungal ribonucleases
5 | d2drpa2 |
|  | 8.9 | 83 | Fold:beta-beta-alpha zinc fingers Superfamily:beta-beta-alpha zinc fingers Family:Classic zinc finger, C2H2
6 | c3a9lB_ |
|  | 8.3 | 21 | PDB header:hydrolase Chain: B: PDB Molecule:poly-gamma-glutamate hydrolase; PDBTitle: structure of bacteriophage poly-gamma-glutamate hydrolase
7 | d2crga1 |
|  | 7.5 | 26 | Fold:DNA/RNA-binding 3-helical bundle Superfamily:Homeodomain-like Family:Myb/SANT domain
8 | c2jo1A_ |
|  | 7.3 | 23 | PDB header:hydrolase regulator Chain: A: PDB Molecule:phospholemman; PDBTitle: structure of the na,k-atpase regulatory protein fxyd1 in2 micelles
9 | c2kaaA_ |
|  | 6.2 | 33 | PDB header:toxin Chain: A: PDB Molecule:hirsutellin a; PDBTitle: solution structure of hirsutellin a from hirsutella2 thompsonii
10 | c2oqbA_ |
|  | 6.2 | 56 | PDB header:transferase,gene regulation Chain: A: PDB Molecule:histone-arginine methyltransferase carm1; PDBTitle: crystal structure of the n-terminal domain of coactivator-associated2 methyltransferase 1 (carm1)
11 | d1isua_ |
|  | 5.9 | 30 | Fold:HIPIP (high potential iron protein) Superfamily:HIPIP (high potential iron protein) Family:HIPIP (high potential iron protein)
12 | c3kdpG_ |
|  | 5.7 | 46 | PDB header:hydrolase Chain: G: PDB Molecule:na+/k+ atpase gamma subunit transcript variant a; PDBTitle: crystal structure of the sodium-potassium pump
13 | c3kdpH_ |
|  | 5.7 | 46 | PDB header:hydrolase Chain: H: PDB Molecule:na+/k+ atpase gamma subunit transcript variant a; PDBTitle: crystal structure of the sodium-potassium pump
14 | c3m8eA_ |
|  | 5.7 | 50 | PDB header:dna binding protein Chain: A: PDB Molecule:putative dna-binding protein; PDBTitle: protein structure of type iii plasmid segregation tubr

Binding site prediction |

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
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Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0