|   |
2 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|  |
Query SS confidence |   |
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
M | K | N | I | L | A | I | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Q | S | H | V | V | Y | G | H | A | G | N | S | A | A | E | F | P | M | R | R | L | G | A | N | V | W | P | L | N | T | V | Q | F | S | N | H | T | Q | Y | G | K | W | T | G | C | V | M | P | P |
Query Conservation |   |
|   |   |
|
|   |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |
|   |   |
|   |   |
|   |   |   |   |
|   |   |   |
|   |   |
|   |   |
|   |
|
|   |   |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
Template Conservation |   |
|   |
|
|   |
|
|
|   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |
|
|
|   | . |   |
|   |   |
|
|   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |
|
|   |
|
Template Sequence |   |
V | A | A | V | V | V | V | G | S | C | M | T | D | L | V | S | L | T | S | R | L | P | K | T | G | E | T | I | H | G | H | K | F | F | I | G | F | G | G | K | G | A | N | Q | C | V | . |
Q | A | A | R | L | G | A | M | T | S | M | V | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
C | K | V | G | K | D |
Template Known Secondary structure |   |
|
| S |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
| S | S |
|
|
| T | T |
|
|
|
|
| S |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  | . |  |  |  |  | T | T |
|
|  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  | S | S |
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  | . |  |  |  |  |
|
|
|
|  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
15 | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | |
. | . | . | . | . | . | . | . | . | 70 | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . |
  |
  |   |
58 | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | 80 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|  |  |  |  |  |
|
|
|
|  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
S | H | L | T | E | I | V | Q | G | I | A | A | I | D | K | L | H | T | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
C | D | A | V | L | S | G | Y | L | G | S | A | E |
Query Conservation |   |
  |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |
|
|
|   |   |
|   |
|   |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |   |
|   |   |   |
|   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
S | F | G | N | D | Y | I | E | N | L | K | Q | N | D | I | S | T | E | F | T | Y | Q | T | K | D | A | A | T | G | T | A | S | I | I | V | N | N | E | G | Q | N | I | I | V | I | V | A | G | A | N | L | L | L | N | T | E | D | L | R | A | A | A | N | V | I | S | R | A | K | V | M | V | C | Q | L | E | I | T | P | A |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  | T | T | T |  |  |
| T | T |  |  |  |  | S | S | S |
|
|  |  |  |  |  |  |  |
| T | T | S |
|  |  |  |  |  |  |
| G | G | G | G | G |
|
|  |  |  |  |  |  | T |  |  |  |  |  |  |
| S |  |  |  |  |
| S | S | S |
|  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
79 | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . |
  |
  |   |
89 | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Q | G | E | H | I | L | G | I | V | R | Q | V | K | A | A | N | P | Q | A | K | Y | F | C | D | P | V | M | G | H | P | E | K | G | C | I | V | A | P | G | V | A | E | F | H | V | R | H | G | L | P | A | S | D | I | I | A | P | N | L | V | E | L | E | I | L | C | E | H | A | V | N | N | V | E | E | A | V | L | A | A |
Query Conservation |   |
  |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |
|
|
|   |
|
|   |   |
|
|   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
T | S | L | E | A | L | T | M | A | R | R | S | . |
. |
. |
. |
. |
G | V | K | T | L | F | N | P | A | P | A | I | A | D | L | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
D | P | Q | F | Y | T | L | S | D | V | F | C | C | N | E | S | E | A | E | I | L | T | G | L | T | V | G | S | A | A | D | A | G | E | A | A |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  | T | . | . | . | . | . | T |
|  |  |  |  |
|
|
| S |
|
| T | T |
| . | . | . | . | . | . | . | . | . | . | . | . |
| T |  |  |  |  | T |
| S |  |  |  |  |  |  |  |  |  |  |  |  |  | S | S |
|
|
| S |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |
| . | . | . | . | . |
|
|  |  |  |  |
|
|
|
|
|
|  |  |
| . | . | . | . | . | . | . | . | . | . | . | . |
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
159 | 160 | . | . | . | . | . | . | . | . | . | 170 | |
|
|
|
|
. | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . |
  |
  |   |
169 | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | |
|
. | . | . | . | . | 240 | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | . | . |  |
|
|
|
|  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
R | E | L | I | A | Q | G | P | Q | I | V | L | V | K | H | L | A | R | A | G | Y | S | R | D | R | F | E | M | L | L | V | T | A | D | E | A | W | H | I | S | R | P | L | V | D | F | G | M | R | Q | P | V | G | V | G | D | V | T | S | G | L | L | L | V | K | L | . |
. |
L | Q | G | A | T | L | Q | E | A | L | E | H |
Query Conservation |   |
  |   |
|   |   |   |
|   |   |   |
|
|
|
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|
|
|   |
|
|
|   |   |   |
|   |
| . | . |   |   |
|   |   |
|   |   |
|
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|
|
|
|
|
|   |
|
|   |
|   |   |
|
|   |   |   |
|   |   |   |   |   |
|
|   |   |
Template Sequence |   |
L | V | L | L | K | R | G | C | Q | V | V | I | I | T | L | G | A | E | G | C | . |
. |
. |
. |
. |
. |
. |
. |
V | V | L | S | Q | T | E | P | E | P | K | H | I | P | T | E | K | V | K | A | V | D | T | T | G | A | G | D | S | F | V | G | A | L | A | F | Y | L | A | Y | Y | P | N | L | S | L | E | D | M | L | N | R |
Template Known Secondary structure |   |
 |  |  |  | T | T | T |
| S |  |  |  |  |  |
| G | G | G |
|  | . | . | . | . | . | . | . | . |  |  |  |  | S | S |
|
| S |
|  |  |  |
|
|
|
|
|
|
| S |
|
| T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| T | T | S |
|  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|  | . | . | . | . | . | . | . | . |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
222 | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | |
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . |
  |
  |   |
247 | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | T | A | A | V | Y | E | I | M | V | T | T | K | A | M | Q | E | Y | E | L | Q | V | V | A | A | Q | D | R | I | A |
Query Conservation |   |
|   |
|   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |
|
|   |   |
|   |   |   |   |   |   |   |
Alig confidence |   |
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   | . | . |   |   |
|
|   |   |
|   |   |   |
|   |   |   |   |   |
|   |   |   |
|
|   |   |   |
|
Template Sequence |   |
S | N | . |
. |
F | I | A | A | V | S | V | Q | A | A | G | T | Q | S | S | Y | P | Y | K | K | D | L | P | L | T | L |
Template Known Secondary structure |   |
 |  | . | . |  |  |  |  |  |  |  | T | S | S | S | G | G | G | G |
|
|
| G | G | G | S |
| G | G | G |
Template Predicted Secondary structure |   |
 |  | . | . |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
294 | . | |
|
. | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . |
  |