|   |
1 | . | . | |
|
. | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | |
|
. | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | |
|
|
60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . |
Predicted Secondary structure |   |
|
|
| . | . |
|  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . | . |
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
| . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Query SS confidence |   |
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
M | P | G | . |
. |
L | K | I | T | L | L | Q | Q | P | L | V | W | M | D | G | P | A | N | L | R | H | F | D | R | Q | L | E | G | I | T | . |
. |
G | R | D | V | I | V | L | P | E | M | F | T | S | G | F | A | M | E | A | A | A | S | S | L | A | Q | . |
. |
. |
D | D | V | V | N | W | M | T | A | K | A | Q | Q | C |
Query Conservation |   |
|   |   | . | . |   |
|
|
|   |   |
|   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |
|
|   |   |
|   | . | . |
|
|
|
|
|
|
|
|
|   |   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |   | . | . | . |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
Alig confidence |   |
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |   |   |   |
|
|
|   |   |
|   |   |   |   | . |   |
|   |   |   |
|   |   |   |
|   |   |   |
|   |   |
|   |   |   |
|
|
|
|
|
|
|
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
Template Sequence |   |
M | A | T | G | R | H | F | I | A | V | C | Q | M | T | S | D | . |
N | D | L | E | K | N | F | Q | A | A | K | N | M | I | E | R | A | G | E | K | K | C | E | M | V | F | L | P | E | C | F | D | F | I | G | L | N | K | N | E | Q | I | D | L | A | M | A | T | D | C | E | Y | M | E | K | Y | R | E | L | A | R | K | H |
Template Known Secondary structure |   |
|
|
| S |  |  |  |  |  |  |  |
| B |
|
|
| . | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
| S |  |  |  |  |
| T | T |
| S |
|
|
| S | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
Template Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
| . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | |
. | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . |
  |
  |   |
74 | . | . | . | . | . | 80 | . | . | . | . | |
|
|
|
. | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | |
. | . | . | . | . | . | . | 110 | . | . | . | . | |
|
|
|
|
|
|
. | . | . | . | . | 120 | . | . | . | . | . | |
. | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 |
Predicted Secondary structure |   |
|  |  |  |  |  |  |
|
|
|
| . | . | . | . |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  | . |  |  |  |  |
|
|
|
|
|
|  |  | . | . | . | . | . | . | . |  |
|
|
|
|
|
|
|
|
|
| . |
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
N | A | L | I | A | G | S | V | A | L | Q | . |
. |
. |
. |
T | E | S | G | S | V | N | R | F | L | L | V | E | P | G | G | T | V | . |
H | F | Y | D | K | R | H | L | F | R | M | A | . |
. |
. |
. |
. |
. |
. |
D | E | H | L | H | Y | K | A | G | N | A | . |
R | V | I | V | E | W | R | G | W | R | I | L | P | L | V |
Query Conservation |   |
  |
|   |
|   |   |   |   |   |   |   | . | . | . | . |   |   |   |   |   |   |
|   |   |   |   |
|   |   |   |
|   |
| . |   |   |   |   |
|   |   |
|   |   |   |   | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |
|   |   | . |   |   |
|   |   |   |   |   |   |   |
|
|   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |
|   |   |   |   |   |   |
|
|
|   |   |
|
Template Sequence |   |
N | I | W | L | S | L | G | G | L | H | H | K | D | P | S | D | A | A | H | P | W | N | T | H | L | I | I | D | S | D | G | V | T | R | A | E | Y | N | K | L | H | L | F | D | L | E | I | P | G | K | V | R | L | M | E | S | E | F | S | K | A | G | T | E | M | I | P | P | V | D | T | P | I | G | R | L | G | L | S | I |
Template Known Secondary structure |   |
T |
|  |  |  |  |  |  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |  |  |  |  |  |
| T | T | S |
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  | T | T | T |  |  |  |  | G | G | G | T |
|
|
|
|
| S |
|
|
|
|  |  |  | T | T |  |  |  |
|
|
|
|
Template Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
89 | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . |
  |
  |   |
141 | . | . | . | . | . | . | . | . | 150 | . | . | . | |
|
. | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | |
170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |
|
|
|
|
|
|  |  |  |  |  |  | . | . |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
| . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
C | Y | D | L | R | F | P | V | W | S | R | N | L | . |
. |
N | D | Y | D | L | A | L | Y | V | A | N | W | P | A | P | R | . |
S | L | H | W | Q | A | L | L | T | A | R | A | I | E | N | Q | A | Y | V | A | G | C | N | R | V | G | S | D | G | N | G | C | H | Y | R | G | D | S | R | V | I | N | P | Q | G | E | I | I |
Query Conservation |   |
|   |
|   |   |   |
|
|   |   |   |   |
| . | . |   |
|
|   |
|
|
|   |   |   |   |   |   |   |   |   | . |   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|   |   |   |
|
|   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |
|   |
|   |
|   |   |
|   |
|   |
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |
|   |   |   |
|   |   |   |
|   |   |   |   |   |
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |   |   |   |
|
|   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |
|   |
|   |
|   |   |
|   |
|   |
|   |
Template Sequence |   |
C | Y | D | V | R | F | P | E | L | S | L | W | N | R | K | R | G | A | Q | L | L | S | F | P | S | A | F | T | L | N | T | G | L | A | H | W | E | T | L | L | R | A | R | A | I | E | N | Q | C | Y | V | V | A | A | A | Q | T | G | A | H | N | P | K | R | Q | S | Y | G | H | S | M | V | V | D | P | W | G | A | V | V |
Template Known Secondary structure |   |
G | G | G | G | G |
|  |  |  |  |  |  |  |  |  | T | T |
| S |  |  |  |
|
| B |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|  |  |  |  |
| B | B |  |  |  |  |  | T | T |  |  |  |  |
|
|
|  |  |  |
| T | T | S |
|  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
169 | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . |
  |
  |   |
218 | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 |
Predicted Secondary structure |   |
 |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | T | A | D | A | H | Q | A | T | R | I | D | A | E | L | S | M | A | A | L | R | E | Y | R | E | K | F | P | A | W | Q | D | A |
Query Conservation |   |
|   |   |   |   |   |   |   |   |
|
|   |
|   |
|
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |
Alig confidence |   |
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   | . |   |   |
|   |   |   |   |   |
|
|
|
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|
Template Sequence |   |
A | Q | C | S | . |
E | R | V | D | M | C | F | A | E | I | D | L | S | Y | V | D | T | L | R | E | M | Q | P | V | F | S | H | R |
Template Known Secondary structure |   |
 |  |
|
| . | S | S | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | S |
| G | G | G |
|
|
Template Predicted Secondary structure |   |
 |  |
|
| . |
|
|
|  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
249 | 250 | . | . | |
. | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 |
  |