|   |
141 | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Y | S | L | A | D | E | K | Q | A | V | N | Q | P | P | E | D | T | P | D | K | N | V | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
G | D | F | D | G | A | F | T | S | A | A | V | K | I | D | A | T | Y | T | T | P | D | Q | S | H | M | A | M | E | P | H | A | S | M | A | V | W |
Query Conservation |   |
  |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|   |   |   |
|
|   |   |
|   |   |
|
|
|   |   |   |   |   |   |   |   |   |
|   |   |
|
|
|   |   |   |
|
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|
|   |
|
|   |   |   |   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |   |
|
|
|   |
|
|   |
|
|
|   |   |
|   |   |   |   |   |   |
|   |   |
|
|
|   |   |   |
|
|   |   |
Template Sequence |   |
V | D | P | F | K | A | M | E | P | D | A | P | L | L | R | E | D | I | K | D | K | M | T | G | A | H | G | A | R | K | H | H | N | H | I | F | R | W | E | I | G | D | K | E | G | T | D | A | T | F | A | K | A | E | V | V | S | K | D | M | F | T | Y | H | R | V | H | P | S | P | L | E | T | C | Q | C | V | A | S | M |
Template Known Secondary structure |   |
|
| G | G | G | T | T | S | T | T |
|
|
|
|
| G | G | G | T | T |
|
|  |  | T | T |  |  |
| S | S | T | T |  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |
| S |  |  |  |  |  |  |  |  |  |
|
| B |
|
|
|
| S | S |
|
|  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|  |  |  |  |
|
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
147 | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . |
  |
  |   |
200 | |
|
. | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 | . | . |
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|  |  |  |  |  |  |
Query SS confidence |   |
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
D | . |
. |
G | N | K | L | T | L | W | T | S | N | Q | M | I | D | W | C | R | T | D | L | A | K | T | L | K | V | P | V | E | N | V | R | I | I | S | P | Y | I | G | G | G | F | G | G | K | L | F | L | R | S | D | A | L | L | A | A | L | A | A | R | A | V | K | R | P | V | K | V | M | L | P | R | P | S | I | P | N |
Query Conservation |   |
| . | . |   |   |   |
|   |
|   |   |
|
|
|   |
|   |   |   |
|   |   |
|
|   |   |
|
|
|
|   |   |   |
|
|
|   |   |   |   |
|
|
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |
|
|
|   |
|   |   |   |
|
|
|
|
|   |   |   |
|
|   |
|   |   |   |
Alig confidence |   |
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |   |
|   |
|   |
|   |   |
|
|
|   |
|   |   |   |
|   |   |
|
|   |   |
|
|
|
|   |   |   |
|
|
|
|   |   |   |
|
|
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |
|
|   |
|
|   |   |   |
|
|
|
|
|
|   |   |
|
|   |
|   |   |   |
Template Sequence |   |
D | K | I | K | G | E | L | T | L | W | G | T | F | Q | A | P | H | V | I | R | T | V | V | S | L | I | S | G | L | P | E | H | K | I | H | V | I | A | P | D | I | G | G | G | F | G | N | K | V | G | A | Y | S | G | Y | V | C | A | V | V | A | S | I | V | L | G | V | P | V | K | W | V | E | D | R | M | E | N | L | S |
Template Known Secondary structure |   |
 | T | T | T | T |  |  |  |  |  |  |
|
| S | S |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| G | G | G |  |  |  |  |
|
|
|
| S |
|
| T | T | T | T | S | S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | S | S |
|  |  |  |  |
|
|  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
227 | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . |
  |
  |   |
278 | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | |
|
|
|
|
|
|
. | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | |
. | . |
Predicted Secondary structure |   |
 |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
| . | . | . | . | . | . | . |
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
| . |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
Query Sequence |   |
N | T | T | H | R | P | A | T | L | Q | H | L | R | I | G | A | D | Q | S | G | K | I | T | A | I | S | H | E | S | W | S | G | N | L | P | G | G | . |
. |
. |
. |
. |
. |
. |
T | P | E | T | A | V | Q | Q | S | E | L | L | Y | A | G | A | N | R | H | T | G | L | R | L | A | T | L | D | L | P | E | G | N | . |
A | M |
Query Conservation |   |
  |   |   |   |
|   |   |   |   |   |   |   |
|   |
|   |   |   |
|
|   |
|   |
|   |   |   |   |   |   |   |   |   |
|   |   |   | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |
|
|   |
|   |   |
| . |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
Template Conservation |   |
  |   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|   |
|   |
|   |   |   |   |   |   |   |
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |
|
|   |   |   |   |   |   |   |
|   |
|
|   |   |
|   |
|   |
|   |
Template Sequence |   |
T | T | S | F | A | R | D | Y | H | M | T | T | E | L | A | A | T | K | D | G | K | I | L | A | M | R | C | H | V | L | A | D | H | G | A | F | D | A | C | A | D | P | S | K | W | P | A | G | F | M | N | I | C | T | G | S | Y | D | M | P | V | A | H | L | A | V | D | G | V | Y | T | N | K | A | S | G | G | V | A | Y |
Template Known Secondary structure |   |
 | S |
|  |  |
|
|  |  |  |  |  |  |  |  |  |
| T | T |
|
|  |  |  |  |  |  |  |  |  |  |  |
|
| S | S |
|
|
|
|
|
| T | T |
| T | T | T | T | G | G | G | T | T | T | T | B |
|
| S |
|  |  |  |  |  |  |  |  |
|
| S | S |
|
|  |  | S |
| S |
Template Predicted Secondary structure |   |
 |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
307 | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . |
  |
  |   |
350 | |
. | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | |
|
|
|
390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | |
|
Predicted Secondary structure |   |
| . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
|
|
|  |  | . | . |
Query SS confidence |   |
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
Query Sequence |   |
R | . |
A | P | G | E | A | P | G | L | M | A | L | E | I | A | I | D | E | L | A | E | K | A | G | I | D | P | V | E | F | R | I | L | N | D | T | Q | V | D | P | . |
. |
. |
. |
A | D | P | T | R | C | F | S | R | R | Q | L | I | E | C | L | R | T | G | A | D | K | F | G | W | K | Q | R | N | A | T | P | G | . |
. |
Query Conservation |   |
| . |
|   |
|   |   |
|   |   |
|
|   |
|   |   |
|
|   |
|
|   |   |
|
|   |
|
|   |
|   |
|   |   |
|   |   |   |   |   |   | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   | . | . |
Alig confidence |   |
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
Template Conservation |   |
|
|
|   |
|   |
|
|   |   |
|
|   |
|   |   |
|
|   |
|
|   |   |
|
|
|
|
|   |
|   |
|   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
R | C | S | F | R | V | T | E | A | V | Y | A | I | E | R | A | I | E | T | L | A | Q | R | L | E | M | D | S | A | D | L | R | I | K | N | F | I | Q | P | E | Q | F | P | Y | M | A | P | L | G | W | E | Y | D | S | G | N | Y | P | L | A | M | K | K | A | M | D | T | V | G | Y | H | Q | L | R | A | E | Q | K | A | K |
Template Known Secondary structure |   |
S |
| T | T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
|  |  |  |  |  |  |  |  | B |
|
| G | G | G |
| S |  |  |
| T | T | S |
|  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  | T |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
387 | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . |
  |
  |   |
|
|
|
|
423 | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
. | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . |
Predicted Secondary structure |   |
. | . | . | . |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
Query SS confidence |   |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
. |
Q | V | R | D | G | E | W | L | V | G | H | G | V | A | A | G | F | R | N | N | L | L | E | K | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
S | G | A | R | V | H | L | E | Q | N | G | T | V | T | V | E | T | D | M | T | D | I | G | T | G | S | Y | T | I | L | A | Q | T | A | A | E | M | L | G | V |
Query Conservation |   |
. | . | . | . |   |   |   |   |
|   |   |   |   |
|   |
|   |
|   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . |   |   |
|   |
|   |
|   |   |
|
|   |
|   |
|   |   |
|   |   |
|   |
|
|
|   |   |
|   |   |   |
|
|   |
|   |   |
|
|
|
Alig confidence |   |
. | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|   |   |
|
|   |
|   |
|   |   |
|   |   |
|   |
|
|
|   |   |
|   |   |
|
|
|   |
|
|   |
|
|
|
Template Sequence |   |
Q | E | A | F | K | R | G | E | T | R | E | I | M | G | I | G | I | S | F | F | T | E | I | V | G | A | G | P | S | K | N | C | D | I | L | G | V | S | M | F | D | S | A | E | I | R | I | H | P | T | G | S | V | I | A | R | M | G | T | K | S | Q | G | Q | G | H | E | T | T | Y | A | Q | I | I | A | T | E | L | G | I |
Template Known Secondary structure |   |
 |  |  |  |  | T | T | S |
| S |  |  |  |  |  |  |  |  |  |  |  |
|
| B | S |
|
|
| T | T | T |
|  |  | T | T |  |  |
|
|  |  |  |  |  |  |  |
| T | T | S |
|  |  |  |  |  | S |
|
|
| S | S | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
Template Predicted Secondary structure |   |
 |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
467 | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . |
  |
  |   |
487 | . | . | 490 | . | . | . | . | . | . | . | . | . | |
500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | |
|
|
|
. | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | |
|
|
550 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |
|
|
|
| . |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|  |  |  | . | . | . |  |
|
|
|
|  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
Query Sequence |   |
P | L | E | Q | V | A | V | H | L | G | D | S | S | . |
F | P | V | S | A | G | S | G | G | Q | W | G | A | N | T | S | T | S | G | V | Y | A | A | C | M | K | L | R | E | M | I | . |
. |
. |
. |
A | S | A | V | G | F | D | P | E | Q | S | Q | F | A | D | G | K | I | T | . |
. |
. |
N | G | T | R | S | A | T | L | H |
Query Conservation |   |
  |   |
|   |
|   |
|   |   |   |
|
|   | . |   |
|   |   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |
|
|   |   |
|   |   |   |
|   |   |   |   | . | . | . | . |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   | . | . | . |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |
|   |
|   |   |   |
|
|   |   |   |
|   |   |   |
|
|   |
|
|
|   |
|   |   |   |
|   |
|
|   |   |
|
|   |   |
|   |   |
|
|   |   |   |
|
|   |   |
|   |   |   |   |   |   |
|   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
P | A | D | D | I | M | I | E | E | G | N | T | D | T | A | P | Y | G | L | G | T | Y | G | S | R | S | T | P | T | A | G | A | A | T | A | V | A | A | R | K | I | K | A | K | A | Q | M | I | A | A | H | M | L | E | V | H | E | G | D | L | E | W | D | V | D | R | F | R | V | K | G | L | P | E | K | F | K | T | M | K |
Template Known Secondary structure |   |
| G | G | G |  |  |  |  |
|
| B | T | T | T | S |
|
|
|
|
| S |
| T | T |
| T | T | T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | S |
| G | G | G |  |  |  |
| S | S |  |  |  |  | T | T |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
547 | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . | . | . | . | . | . | . | 610 | . | . | . | . | . | . | . | . | . | 620 | . | . | . | . | . | . |
  |
  |   |
559 | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | |
|
|
|
|
. | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . | . | . | . | . | . | . | 610 | . | . | . | . | . | . | . | . | . | 620 | . | . | . | . | . | . | . | . | . | 630 | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | A | T | A | G | G | R | L | T | A | E | E | S | I | E | . |
. |
. |
. |
. |
F | G | T | L | S | K | E | Y | Q | Q | S | T | F | A | G | H | F | V | E | V | G | V | H | S | A | T | G | E | V | R | V | R | R | M | L | A | V | C | A | A | G | R | I | L | N | P | K | T | A | R | S | Q | V | I | G | A | M | T | M | G |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|
|
|
|   |   |
|
|   |
|   |
|   |   |   |   |   |
|   |
|   |
|   |
|
|
|
|   |   |
|   |
|
|
|   |
|
|   |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|
|
|
|
|   |   |
|
|   |
|   |
|   |   |   |   |   |   |   |
|   |
|   |
|
|
|
|   |   |
|   |
|
|
|   |
|
|   |   |   |
|
Template Sequence |   |
E | L | A | W | A | S | Y | N | S | P | P | P | N | L | E | P | G | L | E | A | V | N | Y | Y | D | P | P | N | M | T | Y | P | F | G | A | Y | F | C | I | M | D | I | D | V | D | T | G | V | A | K | T | R | R | F | Y | A | L | D | D | C | G | T | R | I | N | P | M | I | I | E | G | Q | V | H | G | G | L | T | E | A |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  | S |
|
| T | T | S |
| S | S |
|  |  |  |  |  |  |
|
| S | S |
| B |
|
|  |  |  |  |  |  |  |  |  |  |  | T | T | T |
|
|  |  |  |  |  |  |  |  |  |  |  |
| B | S |
| S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
627 | . | . | 630 | . | . | . | . | . | . | . | . | . | 640 | . | . | . | . | . | . | . | . | . | 650 | . | . | . | . | . | . | . | . | . | 660 | . | . | . | . | . | . | . | . | . | 670 | . | . | . | . | . | . | . | . | . | 680 | . | . | . | . | . | . | . | . | . | 690 | . | . | . | . | . | . | . | . | . | 700 | . | . | . | . | . | . |
  |
  |   |
634 | . | . | . | . | . | 640 | . | . | . | . | . | . | . | . | . | 650 | . | . | . | . | . | . | . | . | . | 660 | . | . | . | . | . | . | . | . | . | 670 | . | . | . | . | . | . | . | . | . | 680 | . | . | . | . | . | . | . | . | . | 690 | . | . | . | . | . | . | . | . | . | 700 | . | . | . | . | . | . | . | . | . | 710 | |
|
|
Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|  |  |  |
|
|
|
|
|  |  |
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
| . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
Query Sequence |   |
M | G | A | A | L | M | E | E | L | A | V | D | D | R | L | G | Y | F | V | N | H | D | M | A | G | Y | E | V | P | V | H | A | D | I | P | K | Q | E | V | I | F | L | D | D | T | D | P | I | S | S | P | M | K | A | K | G | V | G | E | L | G | L | C | G | V | S | A | A | I | A | N | A | V | Y | N | A | T | . |
. |
. |
Query Conservation |   |
|
|   |
|
|   |
|   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |
|
|   |
|
|
|   |   |
|   |
|   |   |   |
|   |   |
|
|   |   |   |   |   |   |   |
|   |
|
|
|
|
|
|
|   |   |   |   |   |   |   |   |
|
|   |
|
|
|   |
|
|   | . | . | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
Template Conservation |   |
|
|   |
|
|   |
|
|   |   |   |
|   |   | . |
|   |   |   |   |   |   |   |   |   |
|   |
|
|
|   |   |
|   |
|   |   |   |
|   |   |   |
|   |
|   |   | . |   |   |
|   |
|
|
|
|
|
|
|   |   |   |   |   |   |   |
|
|
|
|
|
|
|   |   |
|   |   |   |   |
Template Sequence |   |
F | A | V | A | M | G | Q | E | I | R | Y | D | E | Q | . |
G | N | V | L | G | A | S | F | M | D | F | F | L | P | T | A | V | E | T | P | K | W | E | T | D | Y | T | V | T | P | S | P | . |
H | H | P | I | G | A | K | G | V | G | E | S | P | H | V | G | G | V | P | C | F | S | N | A | V | N | D | A | Y | A | F | L |
Template Known Secondary structure |   |
 |  |  |  |  | T |
|
|
|  |  |
| T | T | . |
|
|  |  | S |
| S | T | T | T | S |
|
|
|
| T | T | T | S |
|
|
|  |  |  |  |
|
|
|
|
| T | . | T | S | T | T | S | B |
|
|
| T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|  |  |  |
|
|
| . |
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
707 | . | . | 710 | . | . | . | . | . | . | . | . | . | 720 | |
. | . | . | . | . | . | . | . | . | 730 | . | . | . | . | . | . | . | . | . | 740 | . | . | . | . | . | . | . | . | . | 750 | . | . | |
. | . | . | . | . | . | . | 760 | . | . | . | . | . | . | . | . | . | 770 | . | . | . | . | . | . | . | . | . | 780 | . | . | . | . |
  |
  |   |
711 | . | . | . | . | . | . | . | . | 720 | . | . | . | . | . | . | . | . | . | 730 |
Predicted Secondary structure |   |
|
|
|  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | I | R | V | R | D | Y | P | I | T | L | D | K | L | L | D | K | L | P | D |
Query Conservation |   |
|   |
|   |   |   |
|
|   |
|
|
|   |
|   |   |
|
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |
|   |   |   |
|
|   |
|
|
|   |
|   |   |
|
|   |   |
Template Sequence |   |
N | A | G | H | I | Q | M | P | H | D | A | W | R | L | W | K | V | G | E | Q |
Template Known Secondary structure |   |
T |
|
|
|
|
| S |
|
|
|  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
785 | . | . | . | . | 790 | . | . | . | . | . | . | . | . | . | 800 | . | . | . | . |
  |