Secondary structure and disorder prediction

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Sequence		M	K	L	P	R	S	S	L	V	W	C	V	L	I	V	C	L	T	L	L	I	F	T	Y	L	T	R	K	S	L	C	E	I	R	Y	R	D	G	Y	R	E	V	A	A	F	M	A	Y	E	S	G	K
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?																																											?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1zll chain E Region: 10 - 25 Aligned: 16 Modelled: 16 Confidence: 31.1% Identity: 25% PDB header:membrane protein/signaling protein Chain: E: PDB Molecule:cardiac phospholamban; PDBTitle: nmr structure of unphosphorylated human phospholamban2 pentamer Phyre2 PDB 3arc chain L Region: 3 - 22 Aligned: 20 Modelled: 20 Confidence: 23.0% Identity: 35% PDB header:electron transport, photosynthesis Chain: L: PDB Molecule:photosystem ii reaction center protein l; PDBTitle: crystal structure of oxygen-evolving photosystem ii at 1.9 angstrom2 resolution Phyre2 PDB 1b24 chain A domain 1 Region: 30 - 51 Aligned: 22 Modelled: 22 Confidence: 12.4% Identity: 18% Fold: Homing endonuclease-like Superfamily: Homing endonucleases Family: Group I mobile intron endonuclease Phyre2 PDB 2krx chain A Region: 27 - 40 Aligned: 14 Modelled: 14 Confidence: 8.4% Identity: 21% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:asl3597 protein; PDBTitle: solution nmr structure of asl3597 from nostoc sp. pcc7120.2 northeast structural genomics consortium target id nsr244. Phyre2 PDB 2wj8 chain N Region: 10 - 23 Aligned: 14 Modelled: 14 Confidence: 7.8% Identity: 29% PDB header:rna binding protein/rna Chain: N: PDB Molecule:nucleoprotein; PDBTitle: respiratory syncitial virus ribonucleoprotein Phyre2 PDB 1y4o chain A domain 1 Region: 28 - 42 Aligned: 15 Modelled: 15 Confidence: 7.7% Identity: 27% Fold: Profilin-like Superfamily: Roadblock/LC7 domain Family: Roadblock/LC7 domain Phyre2 PDB 3a0b chain L Region: 3 - 22 Aligned: 20 Modelled: 20 Confidence: 7.6% Identity: 35% PDB header:electron transport Chain: L: PDB Molecule:photosystem ii reaction center protein l; PDBTitle: crystal structure of br-substituted photosystem ii complex Phyre2 PDB 3prr chain L Region: 3 - 22 Aligned: 20 Modelled: 20 Confidence: 7.6% Identity: 35% PDB header:photosynthesis Chain: L: PDB Molecule:photosystem ii reaction center protein l; PDBTitle: crystal structure of cyanobacterial photosystem ii in complex with2 terbutryn (part 2 of 2). this file contains second monomer of psii3 dimer Phyre2 PDB 3a0h chain L Region: 3 - 22 Aligned: 20 Modelled: 20 Confidence: 7.6% Identity: 35% PDB header:electron transport Chain: L: PDB Molecule:photosystem ii reaction center protein l; PDBTitle: crystal structure of i-substituted photosystem ii complex Phyre2 PDB 3a0h chain L Region: 3 - 22 Aligned: 20 Modelled: 20 Confidence: 7.6% Identity: 35% PDB header:electron transport Chain: L: PDB Molecule:photosystem ii reaction center protein l; PDBTitle: crystal structure of i-substituted photosystem ii complex Phyre2 PDB 3bz2 chain L Region: 3 - 22 Aligned: 20 Modelled: 20 Confidence: 7.6% Identity: 35% PDB header:electron transport Chain: L: PDB Molecule:photosystem ii reaction center protein l; PDBTitle: crystal structure of cyanobacterial photosystem ii (part 22 of 2). this file contains second monomer of psii dimer Phyre2 PDB 3arc chain L Region: 3 - 22 Aligned: 20 Modelled: 20 Confidence: 7.6% Identity: 35% PDB header:electron transport, photosynthesis Chain: L: PDB Molecule:photosystem ii reaction center protein l; PDBTitle: crystal structure of oxygen-evolving photosystem ii at 1.9 angstrom2 resolution Phyre2 PDB 3bz1 chain L Region: 3 - 22 Aligned: 20 Modelled: 20 Confidence: 7.6% Identity: 35% PDB header:electron transport Chain: L: PDB Molecule:photosystem ii reaction center protein l; PDBTitle: crystal structure of cyanobacterial photosystem ii (part 12 of 2). this file contains first monomer of psii dimer Phyre2 PDB 3prq chain L Region: 3 - 22 Aligned: 20 Modelled: 20 Confidence: 7.6% Identity: 35% PDB header:photosynthesis Chain: L: PDB Molecule:photosystem ii reaction center protein l; PDBTitle: crystal structure of cyanobacterial photosystem ii in complex with2 terbutryn (part 1 of 2). this file contains first monomer of psii3 dimer Phyre2 PDB 2axt chain L Region: 3 - 22 Aligned: 20 Modelled: 20 Confidence: 7.6% Identity: 35% PDB header:electron transport Chain: L: PDB Molecule:photosystem ii reaction center l protein; PDBTitle: crystal structure of photosystem ii from thermosynechococcus elongatus Phyre2 PDB 2axt chain L Region: 3 - 22 Aligned: 20 Modelled: 20 Confidence: 7.6% Identity: 35% PDB header:electron transport Chain: L: PDB Molecule:photosystem ii reaction center l protein; PDBTitle: crystal structure of photosystem ii from thermosynechococcus elongatus Phyre2 PDB 2axt chain L domain 1 Region: 3 - 22 Aligned: 20 Modelled: 20 Confidence: 7.6% Identity: 35% Fold: Single transmembrane helix Superfamily: Photosystem II reaction center protein L, PsbL Family: PsbL-like Phyre2 PDB 1s5l chain L Region: 3 - 22 Aligned: 20 Modelled: 20 Confidence: 7.6% Identity: 35% PDB header:photosynthesis Chain: L: PDB Molecule:photosystem ii reaction center l protein; PDBTitle: architecture of the photosynthetic oxygen evolving center Phyre2 PDB 3kzi chain L Region: 3 - 22 Aligned: 20 Modelled: 20 Confidence: 7.6% Identity: 35% PDB header:electron transport Chain: L: PDB Molecule:photosystem ii reaction center protein l; PDBTitle: crystal structure of monomeric form of cyanobacterial photosystem ii Phyre2 PDB 1s5l chain L Region: 3 - 22 Aligned: 20 Modelled: 20 Confidence: 7.6% Identity: 35% PDB header:photosynthesis Chain: L: PDB Molecule:photosystem ii reaction center l protein; PDBTitle: architecture of the photosynthetic oxygen evolving center Phyre2 1 c1zllE_ 2 c3arcl_ 3 d1b24a1 4 c2krxA_ 5 c2wj8N_ 6 d1y4oa1 7 c3a0bl_ 8 c3prrL_ 9 c3a0hl_ 10 c3a0hL_ 11 c3bz2L_ 12 c3arcL_ 13 c3bz1L_ 14 c3prqL_ 15 c2axtL_ 16 c2axtl_ 17 d2axtl1 18 c1s5lL_ 19 c3kziL_ 20 c1s5ll_ 21 22 23 24 25 26 27

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c1zllE_ 31.1 25 PDB header:membrane protein/signaling protein Chain: E: PDB Molecule:cardiac phospholamban; PDBTitle: nmr structure of unphosphorylated human phospholamban2 pentamer 2 c3arcl_ 23.0 35 PDB header:electron transport, photosynthesis Chain: L: PDB Molecule:photosystem ii reaction center protein l; PDBTitle: crystal structure of oxygen-evolving photosystem ii at 1.9 angstrom2 resolution 3 d1b24a1 12.4 18 Fold:Homing endonuclease-like Superfamily:Homing endonucleases Family:Group I mobile intron endonuclease 4 c2krxA_ 8.4 21 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:asl3597 protein; PDBTitle: solution nmr structure of asl3597 from nostoc sp. pcc7120.2 northeast structural genomics consortium target id nsr244. 5 c2wj8N_ 7.8 29 PDB header:rna binding protein/rna Chain: N: PDB Molecule:nucleoprotein; PDBTitle: respiratory syncitial virus ribonucleoprotein 6 d1y4oa1 7.7 27 Fold:Profilin-like Superfamily:Roadblock/LC7 domain Family:Roadblock/LC7 domain 7 c3a0bl_ 7.6 35 PDB header:electron transport Chain: L: PDB Molecule:photosystem ii reaction center protein l; PDBTitle: crystal structure of br-substituted photosystem ii complex 8 c3prrL_ 7.6 35 PDB header:photosynthesis Chain: L: PDB Molecule:photosystem ii reaction center protein l; PDBTitle: crystal structure of cyanobacterial photosystem ii in complex with2 terbutryn (part 2 of 2). this file contains second monomer of psii3 dimer 9 c3a0hl_ 7.6 35 PDB header:electron transport Chain: L: PDB Molecule:photosystem ii reaction center protein l; PDBTitle: crystal structure of i-substituted photosystem ii complex 10 c3a0hL_ 7.6 35 PDB header:electron transport Chain: L: PDB Molecule:photosystem ii reaction center protein l; PDBTitle: crystal structure of i-substituted photosystem ii complex 11 c3bz2L_ 7.6 35 PDB header:electron transport Chain: L: PDB Molecule:photosystem ii reaction center protein l; PDBTitle: crystal structure of cyanobacterial photosystem ii (part 22 of 2). this file contains second monomer of psii dimer 12 c3arcL_ 7.6 35 PDB header:electron transport, photosynthesis Chain: L: PDB Molecule:photosystem ii reaction center protein l; PDBTitle: crystal structure of oxygen-evolving photosystem ii at 1.9 angstrom2 resolution 13 c3bz1L_ 7.6 35 PDB header:electron transport Chain: L: PDB Molecule:photosystem ii reaction center protein l; PDBTitle: crystal structure of cyanobacterial photosystem ii (part 12 of 2). this file contains first monomer of psii dimer 14 c3prqL_ 7.6 35 PDB header:photosynthesis Chain: L: PDB Molecule:photosystem ii reaction center protein l; PDBTitle: crystal structure of cyanobacterial photosystem ii in complex with2 terbutryn (part 1 of 2). this file contains first monomer of psii3 dimer 15 c2axtL_ 7.6 35 PDB header:electron transport Chain: L: PDB Molecule:photosystem ii reaction center l protein; PDBTitle: crystal structure of photosystem ii from thermosynechococcus elongatus 16 c2axtl_ 7.6 35 PDB header:electron transport Chain: L: PDB Molecule:photosystem ii reaction center l protein; PDBTitle: crystal structure of photosystem ii from thermosynechococcus elongatus 17 d2axtl1 7.6 35 Fold:Single transmembrane helix Superfamily:Photosystem II reaction center protein L, PsbL Family:PsbL-like 18 c1s5lL_ 7.6 35 PDB header:photosynthesis Chain: L: PDB Molecule:photosystem ii reaction center l protein; PDBTitle: architecture of the photosynthetic oxygen evolving center 19 c3kziL_ 7.6 35 PDB header:electron transport Chain: L: PDB Molecule:photosystem ii reaction center protein l; PDBTitle: crystal structure of monomeric form of cyanobacterial photosystem ii 20 c1s5ll_ 7.6 35 PDB header:photosynthesis Chain: L: PDB Molecule:photosystem ii reaction center l protein; PDBTitle: architecture of the photosynthetic oxygen evolving center 21 c3a0bL_ not modelled 7.6 35 PDB header:electron transport Chain: L: PDB Molecule:photosystem ii reaction center protein l; PDBTitle: crystal structure of br-substituted photosystem ii complex 22 d1prtc1 not modelled 6.8 29 Fold:OB-fold Superfamily:Bacterial enterotoxins Family:Bacterial AB5 toxins, B-subunits 23 d1h9ra1 not modelled 6.3 17 Fold:OB-fold Superfamily:MOP-like Family:BiMOP, duplicated molybdate-binding domain 24 d2hz5a1 not modelled 6.2 27 Fold:Profilin-like Superfamily:Roadblock/LC7 domain Family:Roadblock/LC7 domain 25 d1h9ma1 not modelled 5.8 24 Fold:OB-fold Superfamily:MOP-like Family:BiMOP, duplicated molybdate-binding domain 26 d1prtb1 not modelled 5.5 29 Fold:OB-fold Superfamily:Bacterial enterotoxins Family:Bacterial AB5 toxins, B-subunits 27 d1h9ma2 not modelled 5.5 20 Fold:OB-fold Superfamily:MOP-like Family:BiMOP, duplicated molybdate-binding domain

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Transmembrane helix prediction

Transmembrane helices have been predicted in your sequence to adopt the topology shown below

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0