Return to main results Retrieve Phyre Job Id

Job DescriptionP30845
Confidence99.78%DateThu Jan 5 11:46:29 GMT 2012
Rank21Aligned Residues243
% Identity16%Templatec2xrgA_
PDB info PDB header:hydrolaseChain: A: PDB Molecule:ectonucleotide pyrophosphatase/phosphodiesterase family PDBTitle: crystal structure of autotaxin (enpp2) in complex with the2 ha155 boronic acid inhibitor
Resolution3.20 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   217..220.........230.........240.........250.........260...... ...270.........280 .........290...
Predicted Secondary structure 

































..







.




Query SS confidence 

















































. .













.












Query Sequence  VRIGEDAHRNPLMQNEKRKNLTILIVGETSRAENFSLNGYPRETNPRLAK. . DNVVYFPNTASCGT. ATAVSVPCMFSDM
Query Conservation                      




  

               

 
  ..     
    
   . 
  
    
   
Alig confidence 






































...







..













.












Template Conservation              



  

 









 


    ...  



  

  

      




 
 


 

 


Template Sequence  VDDDCEEIKVPECPAGFVRPPLIIFSVDGFRASYMKKGS. . . KVMPNIEKLRSCGTHAPYMRPVYPTKTFPNLYTLATGL
Template Known Secondary structure  GGS





S



TT
SS

T

GGGGGS
T...TTSS
S


SS
S
S
Template Predicted Secondary structure 
























...















Template SS confidence 















































































   144.....150.........160.........170.........180.. .......190.........200.........210.........220
 
   294.....300.........310.........320.........330.........340.........350
Predicted Secondary structure  .......................









































Query SS confidence  . . . . . . . . . . . . . . . . . . . . . . .
























































Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . PREHYKEELAQHQEGVLDIIQRAGINVLWNDNDGGCKGACDRVPHQNVTALNLPDQC
Query Conservation  .......................              

   

  

 
                              
Alig confidence  .......................



























..........................


Template Conservation 

  



 
   
                      



 
    
 


..........................   
Template Sequence  YPESHGIVGNSMYDPVFDASFHLRGREKFNHRWWGGQPLWITATKQGVRAG. . . . . . . . . . . . . . . . . . . . . . . . . . TFF
Template Known Secondary structure 
S


SSTTTT
SSSSGGG
TTS

S

TTT

B
..........................


Template Predicted Secondary structure 































..........................
Template SS confidence 















































































   221........230.........240.........250.........260.........270. ...
 
   351........360......... 370.........380.... .....390.........400.........410.........420..
Predicted Secondary structure 





..







......

























Query SS confidence 


















. .














. . . . . .





































Query Sequence  INGECYDEVLFHGLEEYIN. . NLQGDGVIVLHTIGS. . . . . . HGPTYYNRYPPQFRKFTPTCDTNEIQTCTKEQLVNTYD
Query Conservation        
  
       
 ..    
 
    
   ......
 

     
                          
 
Alig confidence 


















..














......






.............................

Template Conservation 



 
   


 
   
       
 

 

  


  

  

 
 
.............................  
Template Sequence  WSVSIPHERRILTILQWLSLPDNERPSVYAFYSEQPDFSGHKYGPFGPE. . . . . . . . . . . . . . . . . . . . . . . . . . . . . MT
Template Known Secondary structure 

TTS
TTS
TTT

S
TT
GG.............................G
Template Predicted Secondary structure 





















.............................
Template SS confidence 















































































   275....280.........290.........300.........310.........320... ..
 
   423......430.........440.........450.........460.
Predicted Secondary structure 













.........................................
Query SS confidence 






































. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Query Sequence  NTLVYVDYIVDKAINLLKEHQDKFTTSLVYLSDHGESLG. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Query Conservation 
 
 
 
  
  

  

      




  



    .........................................
Alig confidence 






































.........................................
Template Conservation   

  

  

 

  

  

 
 
 








  
     
 
              
    
  
     
   
Template Sequence  NPLREIDKTVGQLMDGLKQLRLHRCVNVIFVGDHGMEDVTCDRTEFLSNYLTNVDDITLVPGTLGRIRAKYDPKTIIAAL
Template Known Secondary structure  TT
TTT
S




SSSGGGT
S

TT
BS


TT
Template Predicted Secondary structure 


























Template SS confidence 















































































   326...330.........340.........350.........360.........370.........380.........390.........400.....
 
   462.......470.........480.........490.........
Predicted Secondary structure  ..........................................



















Query SS confidence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .





































Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ENGIYLHGLPYAIAPDSQKQVPMLLWLSEDYQKRYQVD
Query Conservation  ..........................................
                   

  
             
Alig confidence  ..........................................


















.








.........
Template Conservation            

 
  

 
 

    

 



    

        
 



     
 .
 


 

 .........
Template Sequence  TCKKPDQHFKPYMKQHLPKRLHYANNRRIEDIHLLVDRRWHVARKPFQGDHGFDNKVNSMQ. TVFVGYGPT. . . . . . . . .
Template Known Secondary structure  SS
STT

GGGS
GGG


SSTTS
S
TT
S





S
TT
GGG
.B
SSS.........
Template Predicted Secondary structure 



































.


.........
Template SS confidence 















































































   412.......420.........430.........440.........450.........460.........470.. .......480.
 
   500.........510.........520.........530
Predicted Secondary structure 
















Query SS confidence 






























Query Sequence  QNCLQKQAQTQHYSQDNLFSTLLGLTGVETK
Query Conservation               
  

 



 
 

   
Alig confidence  ...



























Template Conservation  ...

 
    

 








 



 

Template Sequence  . . . FKYRTKVPPFENIELYNVMCDLLGLKPA
Template Known Secondary structure  ...B
SS
B


GGGT



Template Predicted Secondary structure  ...














Template SS confidence 






























   494.....500.........510.........520.
 
Download:Text version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
Disclaimer
Terms and Conditions