Job Description P0AFI2 Confidence 100.00% Date Thu Jan 5 11:26:24 GMT 2012 Rank 10 Aligned Residues 435 % Identity 42% Template c2novD_ PDB info PDB header:isomerase Chain: D: PDB Molecule:dna topoisomerase 4 subunit a; PDBTitle: breakage-reunion domain of s.pneumoniae topo iv: crystal2 structure of a gram-positive quinolone target Resolution 2.67 Å

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		30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		A	L	P	F	I	G	D	G	L	K	P	V	Q	R	R	I	V	Y	A	M	S	E	L	G	L	N	A	S	A	K	F	K	K	S	A	R	T	V	G	D	V	L	G	K	Y	H	P	H	G	D	S	A	C	Y	E	A	M	V	L	M	A	Q	P	F	S	Y	R	Y	P	L	V	D	G	Q	G	N	W	G	A	P
Query Conservation
Alig confidence
Template Conservation
Template Sequence		A	L	P	D	I	R	D	G	L	K	P	V	Q	R	R	I	L	Y	S	M	N	K	D	S	N	T	F	D	K	S	Y	R	K	S	A	K	S	V	G	N	I	M	G	N	F	H	P	H	G	D	S	S	I	Y	D	A	M	V	R	M	S	Q	N	W	K	N	R	E	I	L	V	E	M	H	G	N	N	G	S	M
Template Known Secondary structure					B	T	T	T				T	T	T	T	T	T							T	T			S	S	S														T	T	T			S		S										S	S		T	T	T		S	S		S					S
Template Predicted Secondary structure
Template SS confidence
		29	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.
		110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		D	D	P	K	S	F	A	A	M	R	Y	T	E	S	R	L	S	K	Y	S	E	L	L	L	S	E	L	G	Q	G	T	A	D	W	V	P	N	F	D	G	T	L	Q	E	P	K	M	L	P	A	R	L	P	N	I	L	L	N	G	T	T	G	I	A	V	G	M	A	T	D	I	P	P	H	N	L	R	E	V	A
Query Conservation
Alig confidence		.	.																																																														.	.	.	.
Template Conservation		.	.																																																														.	.	.	.
Template Sequence		.	.	D	D	P	P	A	A	M	R	Y	T	E	A	R	L	S	E	I	A	G	Y	L	L	Q	D	I	E	K	K	T	V	P	F	A	W	N	F	D	D	T	E	K	E	P	T	V	L	P	A	A	F	P	N	L	L	V	N	G	S	T	G	I	.	.	.	.	A	T	D	I	P	P	H	N	L	A	E	V	I
Template Known Secondary structure		.	.							T	T	T														S	S	T	T	T	T		S						S	S	S	S	S				S	S				S	S						T		B				.	.	.	.			B	B
Template Predicted Secondary structure		.	.																																																														.	.	.	.
Template SS confidence
				109	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.					170	.	.	.	.	.	.	.	.	.	180	.	.
		190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.					.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.
Predicted Secondary structure																																																												.	.	.	.
Query SS confidence																																																												.	.	.	.
Query Sequence		Q	A	A	I	A	L	I	D	Q	P	K	T	T	L	D	Q	L	L	D	I	V	Q	G	P	D	Y	P	T	E	A	E	I	I	T	S	R	A	E	I	R	K	I	Y	E	N	G	R	G	S	V	R	M	R	A	V	W	K	K	.	.	.	.	E	D	G	A	V	V	I	S	A	L	P	H	Q	V	S	G	A	R
Query Conservation																																																												.	.	.	.
Alig confidence																																.																												.	.	.	.
Template Conservation																																.
Template Sequence		D	A	A	V	Y	M	I	D	H	P	T	A	K	I	D	K	L	M	E	F	L	P	G	P	D	F	P	T	G	A	.	I	I	Q	G	R	D	E	I	K	K	A	Y	E	T	G	K	G	R	V	V	V	R	S	K	T	E	I	E	K	L	K	G	G	K	E	I	V	I	T	E	I	P	Y	E	I	N	K	A	N
Template Known Secondary structure											S	S							T	T	T			S				T	T			.					S									S	S									B							S	S	S							B			T	T
Template Predicted Secondary structure																																.
Template SS confidence
		188	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.		.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.
		266	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		V	L	E	Q	I	A	A	Q	M	R	N	K	K	L	P	M	V	D	D	L	R	D	E	S	D	H	E	N	P	T	R	L	V	I	V	P	R	S	N	R	V	D	M	D	Q	V	M	N	H	L	F	A	T	T	D	L	E	K	S	Y	R	I	N	L	N	M	I	G	L	D	G	R	P	A	V	K	N	L	L	E
Query Conservation
Alig confidence															.	.	.													.											.											.	.	.																.
Template Conservation															.	.	.													.											.											.	.	.																.
Template Sequence		L	V	K	K	I	D	D	V	R	V	N	N	K	.	.	.	V	A	E	V	R	D	E	S	D	R	D	G	.	L	R	I	A	I	E	L	K	K	D	.	A	N	T	E	L	V	L	N	Y	L	.	.	.	T	D	L	Q	I	N	Y	N	F	N	M	V	A	I	D	.	N	F	T	P	R	Q	V	G	I	V	P
Template Known Secondary structure								T	T	T	T	T	T		.	.	.										S	S	S	.								S	S	S	.		S	S	T	T	G	G	G	T		.	.	.			S	S						B						.	T	T							S
Template Predicted Secondary structure															.	.	.													.											.											.	.	.																.
Template SS confidence
		268	.	270	.	.	.	.	.	.	.	.	.	280				.	.	.	.	.	.	.	.	.	290	.	.		.	.	.	.	.	.	.	300	.	.		.	.	.	.	.	.	.	310	.	.				.	.	.	.	.	.	.	320	.	.	.	.	.	.	.		.	.	330	.	.	.	.	.	.	.	.
		346	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.		.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.
Predicted Secondary structure																																																														.
Query SS confidence																																																														.
Query Sequence		I	L	S	E	W	L	V	F	R	R	D	T	V	R	R	R	L	N	Y	R	L	E	K	V	L	K	R	L	H	I	L	E	G	L	L	V	A	F	L	N	I	D	E	V	I	E	I	I	R	N	E	D	E	P	K	P	A	L	M	S	.	R	F	G	L	T	E	T	Q	A	E	A	I	L	E	L	K	L	R	H
Query Conservation																																																														.
Alig confidence																																																														.
Template Conservation
Template Sequence		I	L	S	S	Y	I	A	H	R	R	E	V	I	L	A	R	S	R	F	D	K	E	K	A	E	K	R	L	H	I	V	E	G	L	I	R	V	I	S	I	L	D	E	V	I	A	L	I	R	A	S	E	N	K	A	D	A	K	E	N	L	K	V	D	F	T	E	E	Q	A	E	A	I	V	T	L	Q	L	Y	R
Template Known Secondary structure																																									S										T	S	S	S					T	T																S			G	G	G
Template Predicted Secondary structure
Template SS confidence
		345	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.
		425	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480
Predicted Secondary structure
Query SS confidence
Query Sequence		L	A	K	L	E	E	M	K	I	R	G	E	Q	S	E	L	E	K	E	R	D	Q	L	Q	G	I	L	A	S	E	R	K	M	N	N	L	L	K	K	E	L	Q	A	D	A	Q	A	Y	G	D	D	R	R	S	P	L
Query Conservation
Alig confidence
Template Conservation
Template Sequence		L	T	N	T	D	V	V	V	L	Q	E	E	E	A	E	L	R	E	K	I	A	M	L	A	A	I	I	G	D	E	R	T	M	Y	N	L	M	K	K	E	L	R	E	V	K	K	K	F	A	T	P	R	L	S	S	L
Template Known Secondary structure		G	S	S					T																						S	T	T																T						S	B
Template Predicted Secondary structure
Template SS confidence
		427	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.