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Job DescriptionP76464
Confidence100.00%DateWed Jan 25 15:21:08 GMT 2012
Rank8Aligned Residues535
% Identity15%Templatec2qkiA_
PDB info PDB header:immune system/hydrolase inhibitorChain: A: PDB Molecule:complement c3; PDBTitle: human c3c in complex with the inhibitor compstatin
Resolution2.40 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   264.....270.........280.........290. ........300.........310.........320.........330....
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Query Sequence  VSGKELLVWTAGKKQGEAKPGSEILWTD. . . . . . . . . GLGVMTRGVTDDSGTLQLQHISPERSYILGKDAEGGVFVSENF
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Template Sequence  RLESEETMVLEAHDAQGDVP. VTVTVHDFPGKKLVLSSEKTVLTPATNHMGNVTFTIPANRGRNKFVTVQATFGTQVVEK
Template Known Secondary structure  BTSS

S
.SSS


BS



TTTTSB






TT
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   13......20.........30.. .......40.........50.........60.........70.........80.........90.
 
   335....340.........350.........360.........370.........380.........390.........400.. .......410...
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Query Sequence  FYESEIYNTRLYIFTDRPLYRAGDRVDVKVIGREFHDPLHSSPIVSAPAKLSVLDANGSLLQTVNVTL. DARNGGQGSFR
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Template Sequence  VVLVSLQSGYLFIQTDKTIYTPGSTVLYRIFTVNHKLL. . . . . PVGRTVMVNIENPEGIPVKQDSLSSQNQLGVLPLSWD
Template Known Secondary structure 



S
S
TT

TTS
.....B



TT


TTTTT
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   98.100.........110.........120.........130..... ....140.........150.........160.........170..
 
   414.....420.........430. ........440.........450.........460. ........470.........480........
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Query Sequence  LPENAVAGGYELRLAYRN. . . QVYSSSFRVANYIKPHFEIGLALAKKEFKT. . GEAVSGKLQLLYPDGEPVKNARVQLSL
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Template Sequence  IPELVNMGQWKIRAYYENSPQQVFSTEFEVKEYVLPSFEVIVEPTEKFYYIYNEKGLEVTITARFLYGKKVEG. TAFVIF
Template Known Secondary structure 

SS


TT
TTS






SSSSSTT
TT
TTS
B

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   173......180.........190.........200.........210.........220.........230.........240..... ....250.
 
   489490.........500.........510.........520......... 530.........540.........550.....
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Query Sequence  RAQQLSMVGNDLRYAGRFPVSLEGSETVSDASGHVALNLPA. . . . . . . . . . . . . ADKPSRYLLTVSASDGAAYRVTTTKE
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Template Sequence  GIQD. . . . . . . . . . GEQRISLPESLKRIPIEDGSGEVVLSRKVLLDGVQRAEDLVGKSLYVSATVILHSGSDMVQAERSG
Template Known Secondary structure  S..........SS

GGG
BTT
TT


GGGTT
TTSS
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   252... ....260.........270.........280.........290.........300.........310.........320.
 
   556...560.........570.........580.........590.........600..... ....610.........620...... ...630...
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Query Sequence  ILIERGLAHYSLSTAAQYSNSGESVVFRYAALESSKQVPVTYEWLRLEDR. TSHSGELPSGGKSFTVNFAKP. GNYNLTL
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Template Conservation 
        
          

      
 
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Template Sequence  IPIVTSPYQIHFTKTPKYFKPGMPFDLMVFVT. NPDGSPAYRVPVAVQGEDTVQSLTQGDGVAKLSINTHPSQKPLSITV
Template Known Secondary structure  S
S

TTS
S
TTS.
TTS
B

S
SSSGGG


TTS

S

S
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   324.....330.........340.........350..... ....360.........370.........380.........390.........400..
 
   634.....640 .........650.........660.........670.........680....... ..690.........700.
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Query Sequence  RDKDGLI. . . . . LAGLSHAVSGKGSTAHTGTVDIVADKTLYQPGETAKMLITFPEPIDE. . . . . . . ALLTLERDRVEQQS
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Template Conservation                           
 
   
 
         
    
 
                
 
 


 

   
Template Sequence  RTKKQELSEAEQATRTMQALPYSTVGNSNNYLHLSVLRTELRPGETLNVNFLLRMDRAHEAKIRYYTYLIMNKGRLLKAG
Template Known Secondary structure 

TTS
TTTS



TTS





S


TT

TTTGGG

TT
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   403......410.........420.........430.........440.........450.........460.........470.........480..
 
   702.......710.........720.........730.........740.. .......750........ .760.........770.....
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Query Sequence  LLSHPANWLTLQRLNDTQYEARVPVSNSFAPNITFSVLYTR. . . . . NGQYSFQNAGIKVAVP. QLDIRVKTDKTHYQPGE
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Template Conservation       ........           
     
   
 
  
        
 
 

    
       
 
        

 
Template Sequence  RQVRE. . . . . . . . PGQDLVVLPLSITTDFIPSFRLVAYYTLIGASGQREVVADSVWVDVKDSCVGSLVVKSGQSQPVPGQ
Template Known Secondary structure 

........TT
S
GGG
S
SSS





SS
S




TT
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   483.... ..490.........500.........510.........520.........530.........540.........550....
 
   776...780.........790.........800.........810.........820.........
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Query Sequence  LVNVELTSSLKGKPVSAQLTVGVVDEMIYALQPEIAPNIGKFFYPLGRNNVRTS
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Template Sequence  QMTLKIEGDHG. . . . . ARVVLVAVDKGVFVLNKKNKLTQSKIWDVVEKADIGCT
Template Known Secondary structure 



TT.....








T

TT


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   558.560........ .570.........580.........590.........600......
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
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