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Job DescriptionP76464
Confidence100.00%DateWed Jan 25 15:21:08 GMT 2012
Rank2Aligned Residues1125
% Identity14%Templatec2b39B_
PDB info PDB header:immune systemChain: B: PDB Molecule:c3; PDBTitle: structure of mammalian c3 with an intact thioester at 3a resolution
Resolution3.00 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   339340.........350.........360.........370.........380.........390......... 400.........410.......
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Query Sequence  EIYNTRLYIFTDRPLYRAGDRVDVKVIGREFHDPLHSSPIVSAPAKLSVLDANGSLLQTVN. VTLDARNGGQGSFRLPEN
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Template Sequence  SLQSGYLFIQTDKTIYTPGSTVLYRVFTVDHKLL. . . . . PVGQTVFITIETPDGIPVKRDSKSSQNQFGILTLSWNIPEL
Template Known Secondary structure 




S
S
TT
TTT.....


TTTTTTTS

SS
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   123......130.........140.........150...... ...160.........170.........180.........190.......
 
   418.420.........430. ........440.........450.........460.. .......470.........480. ........490.
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Query Sequence  AVAGGYELRLAYRN. . . QVYSSSFRVANYIKPHFEIGLALAKKEFKTG. . EAVSGKLQLLYPDGEPVKN. ARVQLSLRAQ
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Template Sequence  VNMGVWKIKAYYEDSPQQVFSAEFEVKEYVLPSFEVQLEPEEKFYYIDDPDGLKVNIIARFLYGEQVDGTAFVIFGVQDG
Template Known Secondary structure 




TT

SS
B







S
SSSS

S

SS


TTS
B




S
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   198.200.........210.........220.........230.........240.........250.........260.........270.......
 
   492.......500.........510.........520.........530... ......540.... .....550........
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Query Sequence  QLSMVGNDLRYAGRFPVSLEGSETVSDASGHVALNLPAADKP. . . . . . . . . . . SRYLLTVSASD. . GAAYRVTTTKEILI
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Template Sequence  DRRISLTHS. . . . . . . . . . LTRVPINDGNGEAILKRQVLLNGVQPSRADALVGKSIYVSATVILQSGSDMVEAERTGIPI
Template Known Secondary structure  S


GGG..........


SS


GGGTSSTT
S
SSSTTTT
TTT


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   278.280...... ...290.........300.........310.........320.........330.........340.......
 
   559560.........570.........580.........590.........600.........610.........620.... .....630.......
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Query Sequence  ERGLAHYSLSTAAQYSNSGESVVFRYAALESSKQVPVTYEWLRLEDRTSHSGELPSGGKSFTVNFA. KPGNYNLTLRDKD
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Template Conservation        
          

 
    
 
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Template Sequence  VTSPYQIHFTKTPKFFKPAMPFDLMVYVT. NPDGSPARHIPVVTQGSNVQSLTQDDGVAKLSINTQNKRDPLTITVRTKK
Template Known Secondary structure 
SSS
SSS
S


TTS


.BTTTB

SSB
TT

B

B
SSSSB





S

S
B




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   348.350.........360.........370...... ...380.........390.........400.........410.........420......
 
   638.640.........650.........660.........670.........680...... ...690.........700.....
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Query Sequence  . . . . . GLILAGLSHAVSGKGSTAHTGTVDIVADKTLYQPGETAKMLITFPEPID. . . . . . . EALLTLERDRVEQQSLLSH
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Template Conservation                       
 
   
 
         
    
 
           
    
 
 


 

       
Template Sequence  DNIPEGRQATRTMQALPYNTQGNSNNYLHLSVPRVELKPGETLNVNFHLRTDPGEQAKIRYYTYMIMNKGKLLKVGRQYR
Template Known Secondary structure  TTS
TTS






B




SSS









SSS

SSGGGT



TT


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   427..430.........440.........450.........460.........470.........480.........490.........500......
 
   706...710.........720.........730.........740.... .....750........ .760.........770......
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Query Sequence  PANWLTLQRLNDTQYEARVPVSNSFAPNITFSVLYTRNG. . . . . QYSFQNAGIKVAVP. . . . QLDIRVKTDKTHYQPGEL
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Template Sequence  E. . . . . . . . PGQDLVVLPLTITSDFIPSFRLVAYYTLINAKGQREVVADSVWVDVKDSCMGTLVVKNGGKEEKHHRPGQQ
Template Known Secondary structure 
........TT
S




STTSS

B
TTS
B



S

SS

SS


S
B
TT
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   507 ..510.........520.........530.........540.........550.........560.........570........
 
   777..780.........790.........800.........810.........820.........830........
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Query Sequence  VNVELTSSLKGKPVSAQLTVGVVDEMIYALQPEIAPNIGKFFYPLGRNNVRTSSSLSFISYD. . . . . . . . . . . . . . . . . .
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Template Sequence  ITLKIEADQG. . . . . ARVGLVAVDKGVFVLNKKNKLTQRKIWDVVEKADIGCTPGSGRNYAGVFTDAGLTLKTSQGLETQ
Template Known Secondary structure 

TT.....


BTTSGGGS

TTTS
S
SS

STB



TT




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   579580........ .590.........600.........610.........620.........630.........640.........650...
 
   839840.........850
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . QALSSEPVAPGA
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Template Conservation                                    
    
       
                                
Template Sequence  QRADPQCPQSVQLMEKRMDKAGQYSSDLRKCCEDGMRDNPMKFPCQRRAQFILQGDACVKAFLDCCEYITQLRQQHSRDG
Template Known Secondary structure 



SS




SSS

GGGTTSS

SS


GGGB
S
TTTTS
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   654.....660.........670.........680.........690.........700.........710.........720.........730...
 
   851........860.........870.... .....880.........890.........900.........910...... ...920....
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Query Sequence  TNRSERRVKMLERPRREEVDTAAW. . . . . MPSLTTDKQGKAYFTFLMPDSLTRWRITARGMNGDGLVGQGR. AYLRSEKN
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Template Sequence  ALDDDIIPEEDIISRSQFPESWLWTVIEDLKQADKNGISTKLMNVFLKDSITTWEILAVSLSDKKGICVADPYEVTVMQD
Template Known Secondary structure 



S



SS
















S

SSS




SSS
TTT


B

S
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   741........750.........760.........770.........780.........790.........800.........810.........820
 
   925....930.........940.........950.. .......960....... ..970...... ...980.........990..
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Query Sequence  LYMKWSMPTVYRVGDKPAAGLFIFSQQD. NEPVALVTKFAGAEM. . . . . . . . . . RQTLTLHKG. ANYISLTQNIQQSGLL
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Template Conservation 
 
   

 

  

   
 
 
 

       
 
 
                   
 
 
     
 
 
 
   
  
Template Sequence  FFIDLRLPYSVVRNEQVEIRAILYNYREAENLKVRVELLYNPAFCSLATAKKRHQQTITIPARSSVAVPYVIVPLKIGLH
Template Known Secondary structure 

S
SS


SS




TT
SS
SS



SS



S
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   828.830.........840.........850.........860.........870.........880.........890.........900.......
 
   993..... .1000.........1010.........1020....... ..1030.........1040.........1050...
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Query Sequence  SAELQQ. . . NGQVQDSISTKLSFVDNSWPVEQQKNVML. . . . . . . . . . . . . . . . GGGDNALMLPEQASNIRLQSSETPQE
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Template Sequence  EVEVKAAVYNHFISDGVKKTLKVVPEGVRVNKTVAVRTLNPEHLGQGGVQREEVPAADLSDQVPDTESETKILLQGTPVA
Template Known Secondary structure  TTS


SS



BTTB




TTB
TT

SSTT
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   908.910.........920.........930.........940.........950.........960.........970.........980.......
 
   1054.. ...1060.........1070.........1080.........1090.... .....1100.........1110.........1120.
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Query Sequence  IFR. . . . . . NNLDALVDEPWGGVINTGSRLIPLSLAWRSLADHQSAA. . . . . . ANDIRQMIQDNRLRLMQLAGPGARFTW
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Template Sequence  QMTEDAIDGERLKHLIQTPSGCGEQNMIGMTPTVIAVHYLDSTDQWEKFGLEKRQESLELIRKGYTQQLAFRQKSSAYAA
Template Known Secondary structure  STTTGGGS
SS


STTGGGGGTT
GGGS
TTTTB
TTS
B
S
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   988.990.........1000.........1010.........1020.........1030.........1040.........1050.........1060.......
 
   1122.......1130.........1140.........1150.........1160... ......1170... ...
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Query Sequence  WGEDGNGDAFLTAWAWYADWQASQAIGVTQQPEYWQHMLDSY. AEQADNMPLL. . . . . . . . . . . . . . . . . . . . . . . . HRA
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Template Sequence  FQYR. PPSTWLTAYVVKVFALAANL. . IAIDSKDLCETVKWLILEKQKPDGIFQEDGPVIHQEMIGGFRDTREKDVSLTA
Template Known Secondary structure  STTS.


TTT..S


TB
TTS
B


S


SGGGS

TT

SSTT
Template Predicted Secondary structure 



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   1068.1070. ........1080.........1090. ........1100.........1110.........1120.........1130.........1140....
 
   1177..1180...... ...1190.........1200.........1210.........1220.........1230.........1240.........1250..
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Query Sequence  LVLAWAQEMN. . . . LPCKTLLKGLDEAIARRGTKTEDFSEEDTRDINDSLILDTPESPLADAVANVLTMTLLKKAQLKST
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Template Sequence  FVLIALHEAKDICEAQVNSLGRSIAKAGDFLENHYRELRRPYTVAIAAYALALLGKLEG. . . . . DRLTKFLNTAKEKNRW
Template Known Secondary structure  TTTTTTTT
SSGGG

STT


T.....T
BTTTB
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   1145....1150.........1160.........1170.........1180.........1190.........1200... ......1210.........
 
   1253......1260.........1270.........1280.........1290..... ....1300.........1310.........1320.....
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Query Sequence  VMPQVQQYAWDKAANSNQPLAHTVVLLNSGGDATQTAAILSGL. . . . . . . TAEQSTIERALAMNWLAKYMATMPPVVLPA
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Template Sequence  . . . . . . . EEPNQKLYNVEATSYALLALLARKDYDTTPPVVRWLNEQRYYGGGYGSTQATFMVFQALAQYQKDVPDHKELN
Template Known Secondary structure  .......

SS
TT
GGG



BTTBB
SS

STT
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   1220.........1230.........1240.........1250.........1260.........1270.........1280.........1290..
 
   1326...1330.........1340......... 1350.........1360.........1370.........1380.........1390...
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Query Sequence  PAGAWAKHKLTGGGEDWRWVGQGV. . . . . . . . . . . . PDILSFGDELSPQNVQVRWREPAKMAQQSNIPVTVERQLYRLIP
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Template Sequence  LDVSIQLPSRNSAVRHRILWESASLLRSEETKENERFTVKAEGKGQGTLSVVTVYHAKLKGKVSCK. KFDLRVSIRPA. .
Template Known Secondary structure 
SSSSS
SSSS
SSS


SS




TTSS
B.S
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   1293......1300.........1310.........1320.........1330.........1340.........1350........ .1360.........
 
   1394.....1400.........1410.........1420.........1430.........1440.........1450.........1460.........1470...
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Query Sequence  GEEEMSFILQPVTSNEIDSDALYLDEITLTSEQDAVLRYGQVEVPLPPGADVERTTWGISVNKPNAAKQQGQLLEKARNE
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Template Sequence  . . . . . . . . . PETVKKPQDAKGSMILDICTKYLGDQDATMSILDISMMTGFSPDVEDLKTLSTGVDRYISKYEMNR. DSNK
Template Known Secondary structure  .........
TTS


TTSS

SSS
B
S

TT
SSB
S
SS.SSSS
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   1370.........1380.........1390.........1400.........1410.........1420.........1430..... ....
 
   1474.....1480.........1490.........1500......... 1510.........1520.
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Query Sequence  MGELAYMVPVKELTGTVTFRHLLRFSQKGQFVLPPA. RYVRSYAPAQQS
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Template Sequence  NTLIIYLDKVSH. TVEDCLSFKVHQYFNVGLIQPGAVKVYSYYNLDETC
Template Known Secondary structure 
S
B
S.SS

SS


TT
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   1440.........1450. ........1460.........1470.........1480.......
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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