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Job DescriptionP76464
Confidence100.00%DateWed Jan 25 15:21:08 GMT 2012
Rank5Aligned Residues645
% Identity13%Templatec2a73B_
PDB info PDB header:immune systemChain: B: PDB Molecule:complement c3; PDBTitle: human complement component c3
Resolution3.30 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   849850.........860.........870.........880... ......890.........900.........910...... ...920...
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Query Sequence  GATNRSERRVKMLERPRREEVDTAAWMPSLTTDKQ. . . . GKAYFTFLMPDSLTRWRITARGMNGDGLVGQGR. AYLRSEK
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Template Sequence  ARALDEDIIAEENIVSRSEFPESWLWNVEDLKEPPKNGISTKLMNIFLKDSITTWEILAVSMSDKKGICVADPFEVTVMQ
Template Known Secondary structure  TT








S



















S

BTTB









S



TTT




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   717..720.........730.........740.........750.........760.........770.........780.........790......
 
   924.....930.........940.........950. ........960....... ..970...... ...980.........990.
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Query Sequence  NLYMKWSMPTVYRVGDKPAAGLFIFSQQ. DNEPVALVTKFAGAEM. . . . . . . . . . RQTLTLHKG. ANYISLTQNIQQSGL
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Template Sequence  DFFIDLRLPYSVVRNEQVEIRAVLYNYRQNQELKVRVELLHNPAFCSLATTKRRHQQTVTIPPKSSLSVPYVIVPLKTGL
Template Known Secondary structure  S

STT


SS




TT
S

SSS

TT
S
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   806...810.........820.........830.........840.........850.........860.........870.........880.....
 
   992...... .1000.........1010.........1020....... ..1030.........1040.........1050..
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Query Sequence  LSAELQQ. . . NGQVQDSISTKLSFVDNSWPVEQQKNVML. . . . . . . . . . . . . . . . GGGDNALMLPEQASNIRLQSSETPQ
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Template Sequence  QEVEVKAAVYHHFISDGVRKSLKVVPEGIRMNKTVAVRTLDPERLGREGVQKEDIPPADLSDQVPDTESETRILLQGTPV
Template Known Secondary structure  SSS


SS


TBTTTBSS






TTB
TT


SSSS
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   886...890.........900.........910.........920.........930.........940.........950.........960.....
 
   1053..... .1060.........1070.........1080.........1090..... ....1100.........1110.........1120
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Query Sequence  EIFRNN. . . . . . LDALVDEPWGGVINTGSRLIPLSLAWRSLADHQSAAA. . . . . . NDIRQMIQDNRLRLMQLAGPGARFT
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Template Sequence  AQMTEDAVDAERLKHLIVTPSGCGEQNMIGMTPTVIAVHYLDETEQWEKFGLEKRQGALELIKKGYTQQLAFRQPSSAFA
Template Known Secondary structure  S
TTTGGGG
SS


STTGGGGGTTT

TTTS

TTT

B
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   966...970.........980.........990.........1000.........1010.........1020.........1030.........1040.....
 
   1121........1130.........1140.........1150.........1160.........1170 .........1180.
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Query Sequence  WWGEDGNGDAFLTAWAWYADWQASQAIGVTQQPEYWQHMLDSYAEQADNM. . . . . . . . . . . . . . . . . . . PLLHRALVLAW
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Template Sequence  AFVKR. APSTWLTAYVVKVFSLAVNL. . IAIDSQVLCGAVKWLILEKQKPDGVFQEDAPVIHQENNNEKDMALTAFVLIS
Template Known Secondary structure  SSSSS.
B
TTTTT..S


B
TTS
B


S

SS



TT
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   1046...1050 .........1060.........1070 .........1080.........1090.........1100.........1110.........1120..
 
   1182.......1190 .........1200.........1210.........1220.........1230.........1240.........1250.......
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Query Sequence  AQEMNLPCK. . . . TLLKGLDEAIARRGTKTEDFSEEDTRDINDSLILDTPESPLADAVANVLTMTLLKKAQLKSTVMPQV
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Template Sequence  LQEAKDICEEQVNSLPGSITKAGDFLEANYMNLQRSYTVAIAGYALAQMGRLKGPLLNKFLTT. . . . . . . . . . . . AKDKN
Template Known Secondary structure  TTTSTTT
TTGGG

STTT


T............SBTTT
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   11291130.........1140.........1150.........1160.........1170.........1180.........1190. .....
 
   1258.1260.........1270.........1280.........1290..... ....1300.........1310.........1320... ......
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Query Sequence  QQYAWDKAANSNQPLAHTVVLLNSGGDATQTAAILSGL. . . . . . . TAEQSTIERALAMNWLAKYMATMPPVVL. PAPAGA
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Template Sequence  RWEDPGKQLYNVEATSYALLALLQLKDFDFVPPVVRWLNEQRYYGGGYGSTQATFMVFQALAQYQKDAPDHQELNLDVSL
Template Known Secondary structure  B


SS
TT
TTTT


BSSS

S
SS



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   1197..1200.........1210.........1220.........1230.........1240.........1250.........1260.........1270......
 
   1330.........1340 .........1350.........1360.........1370.........1380.........1390........
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Query Sequence  WAKHKLTGGGE. . . . . . . . . . . DWRWVGQGVPDILSFGDELSPQNVQVRWREPAKMAQQSNIPVTVERQLYRLIPGEEEM
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Template Sequence  QLPSRSSKITHRIHWESASLLRSEETKENEGFTVTAEGKGQGTLSVVTMYHAKAKDQLT. CNKFDLKVTIKPA. . . . . . .
Template Known Secondary structure 
TT
SS
SSSS

SS




SS






S
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SS
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   1277..1280.........1290.........1300.........1310.........1320.........1330..... ....1340........
 
   13991400.........1410.........1420.........1430.........1440.........1450.........1460.........1470........
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Query Sequence  SFILQPVTSNEIDSDALYLDEITLTSEQDAVLRYGQVEVPLPPGADVERTTWGISVNKPNAAKQQGQLLEKARNEMGELA
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Template Sequence  . . . . PETEKRPQDAKNTMILEICTRYRGDQDATMSILDISMMTGFAPDTDDLKQLANGVDRYISKYELDKAFSDRNTLII
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TTS


SS
S
SSS
B
S

SS
SSS
S
S




SSSS
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   13491350.........1360.........1370.........1380.........1390.........1400.........1410.........1420....
 
   14791480.........1490.........1500. ........1510.........1520.
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Query Sequence  YMVPVKELTGTVTFRHLLRFSQK. GQFVLPPARYVRSYAPAQQS
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Template Sequence  YLDKVSH. SEDDCLAFKVHQYFNVELIQPGAVKVYAYYNLEESC
Template Known Secondary structure  S
B
S.SS


SS
S


TT
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   1425....1430. ........1440.........1450.........1460.......
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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