Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP67444
DateThu Jan 5 12:10:37 GMT 2012
Unique Job ID164ee76df6845934

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c3qe7A_
Top template information
PDB header:transport protein
Chain: A: PDB Molecule:uracil permease;
PDBTitle: crystal structure of uracil transporter--uraa
Confidence and coverage
Confidence:100.0% Coverage: 86%
401 residues ( 86% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MSDINHAGSDLIFELEDRPPFHQALVGAITHLLAIFVPMVTPALIVGAALQLSAETTAYL
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Disorder  ????????????
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   .........70.........80.........90.........100.........110.........120
Sequence  VSMAMIASGIGTWLQVNRYGIVGSGLLSIQSVNFSFVTVMIALGSSMKSDGFHEELIMSS
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   .........130.........140.........150.........160.........170.........180
Sequence  LLGVSFVGAFLVVGSSFILPYLRRVITPTVSGIVVLMIGLSLIKVGIIDFGGGFAAKSSG
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?
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   .........190.........200.........210.........220.........230.........240
Sequence  TFGNYEHLGVGLLVLIVVIGFNCCRSPLLRMGGIAIGLCVGYIASLCLGMVDFSSMRNLP
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   .........250.........260.........270.........280.........290.........300
Sequence  LITIPHPFKYGFSFSFHQFLVVGTIYLLSVLEAVGDITATAMVSRRPIQGEEYQSRLKGG
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   .........310.........320.........330.........340.........350.........360
Sequence  VLADGLVSVIASAVGSLPLTTFAQNNGVIQMTGVASRYVGRTIAVMLVILGLFPMIGGFF
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   .........370.........380.........390.........400.........410.........420
Sequence  TTIPSAVLGGAMTLMFSMIAIAGIRIIITNGLKRRETLIVATSLGLGLGVSYDPEIFKIL
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   .........430.........440.........450.........460......
Sequence  PASIYVLVENPICAGGLTAILLNIILPGGYRQENVLPGITSAEEMD
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?????????????????
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Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 3qe7 chain A

3D model

Region: 11 - 447
Aligned: 401
Modelled: 426
Confidence: 100.0%
Identity: 23%
PDB header:transport protein
Chain: A: PDB Molecule:uracil permease;
PDBTitle: crystal structure of uracil transporter--uraa

Phyre2

PDB 1pw4 chain A

3D model

Region: 1 - 462
Aligned: 425
Modelled: 438
Confidence: 56.0%
Identity: 11%
Fold: MFS general substrate transporter
Superfamily: MFS general substrate transporter
Family: Glycerol-3-phosphate transporter

Phyre2

PDB 2w8a chain C

3D model

Region: 140 - 466
Aligned: 299
Modelled: 310
Confidence: 24.3%
Identity: 12%
PDB header:membrane protein
Chain: C: PDB Molecule:glycine betaine transporter betp;
PDBTitle: crystal structure of the sodium-coupled glycine betaine2 symporter betp from corynebacterium glutamicum with bound3 substrate

Phyre2

PDB 1bzk chain A

3D model

Region: 18 - 51
Aligned: 34
Modelled: 34
Confidence: 22.3%
Identity: 21%
PDB header:transport protein
Chain: A: PDB Molecule:protein (band 3 anion transport protein);
PDBTitle: structural studies on the effects of the deletion in the2 red cell anion exchanger (band3, ae1) associated with3 south east asian ovalocytosis.

Phyre2

PDB 3org chain B

3D model

Region: 139 - 448
Aligned: 290
Modelled: 291
Confidence: 17.7%
Identity: 12%
PDB header:transport protein
Chain: B: PDB Molecule:cmclc;
PDBTitle: crystal structure of a eukaryotic clc transporter

Phyre2

PDB 3lpz chain A

3D model

Region: 305 - 318
Aligned: 14
Modelled: 14
Confidence: 9.7%
Identity: 21%
PDB header:protein transport
Chain: A: PDB Molecule:get4 (yor164c homolog);
PDBTitle: crystal structure of c. therm. get4

Phyre2

PDB 3nd0 chain A

3D model

Region: 276 - 442
Aligned: 167
Modelled: 167
Confidence: 6.9%
Identity: 10%
PDB header:transport protein
Chain: A: PDB Molecule:sll0855 protein;
PDBTitle: x-ray crystal structure of a slow cyanobacterial cl-/h+ antiporter

Phyre2
1

c3qe7A_
2

d1pw4a_
3

c2w8aC_
4

c1bzkA_
5

c3orgB_
6

c3lpzA_
7

c3nd0A_



Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c3qe7A_



100.0 23 PDB header:transport protein
Chain: A: PDB Molecule:uracil permease;
PDBTitle: crystal structure of uracil transporter--uraa
2d1pw4a_



56.0 11 Fold:MFS general substrate transporter
Superfamily:MFS general substrate transporter
Family:Glycerol-3-phosphate transporter
3c2w8aC_



24.3 12 PDB header:membrane protein
Chain: C: PDB Molecule:glycine betaine transporter betp;
PDBTitle: crystal structure of the sodium-coupled glycine betaine2 symporter betp from corynebacterium glutamicum with bound3 substrate
4c1bzkA_



22.3 21 PDB header:transport protein
Chain: A: PDB Molecule:protein (band 3 anion transport protein);
PDBTitle: structural studies on the effects of the deletion in the2 red cell anion exchanger (band3, ae1) associated with3 south east asian ovalocytosis.
5c3orgB_



17.7 12 PDB header:transport protein
Chain: B: PDB Molecule:cmclc;
PDBTitle: crystal structure of a eukaryotic clc transporter
6c3lpzA_



9.7 21 PDB header:protein transport
Chain: A: PDB Molecule:get4 (yor164c homolog);
PDBTitle: crystal structure of c. therm. get4
7c3nd0A_



6.9 10 PDB header:transport protein
Chain: A: PDB Molecule:sll0855 protein;
PDBTitle: x-ray crystal structure of a slow cyanobacterial cl-/h+ antiporter

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite



Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0