Job Description P0A953 Confidence 100.00% Date Thu Jan 5 11:09:24 GMT 2012 Rank 16 Aligned Residues 387 % Identity 24% Template c3hhdC_ PDB info PDB header:transferase, hydrolase Chain: C: PDB Molecule:fatty acid synthase; PDBTitle: structure of the human fatty acid synthase ks-mat didomain2 as a framework for inhibitor design. Resolution 2.15 Å

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		2	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.			.	.	.	50	.	.	.					.	.	.	.	.	.		60	.	.	.	.	.	.	.	.	.	70	.	.	.	.
Predicted Secondary structure																																															.	.								.	.	.	.							.
Query SS confidence																																															.	.								.	.	.	.							.
Query Sequence		K	R	A	V	I	T	G	L	G	I	V	S	S	I	G	N	N	Q	Q	E	V	L	A	S	L	R	E	G	R	S	G	I	T	F	S	Q	E	L	K	D	S	G	M	R	S	.	.	H	V	W	G	N	V	K	.	.	.	.	L	D	T	T	G	L	.	I	D	R	K	V	V	R	F	M	S	D	A	S	I	Y
Query Conservation																																															.	.								.	.	.	.							.
Alig confidence																																															.	.								.	.	.	.							.
Template Conservation
Template Sequence		E	E	V	V	I	A	G	M	S	G	K	L	P	E	S	E	N	L	Q	E	F	W	D	N	L	I	G	G	V	D	M	V	T	D	D	D	R	R	W	K	A	G	L	Y	G	L	P	R	R	S	G	K	L	K	D	L	S	R	F	D	A	S	F	F	G	V	H	P	K	Q	A	H	T	M	D	P	Q	L	R	L
Template Known Secondary structure													B	T	T	B	S	S										T	T							S	S	S	S	S		T	T	G	G	G			S						S		S					T	T	T	T	T								T	S
Template Predicted Secondary structure
Template SS confidence
		2	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.
		75	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		A	F	L	S	M	E	Q	A	I	A	D	A	G	L	S	P	E	A	Y	Q	N	N	P	R	V	G	L	I	A	G	S	G	G	G	S	P	R	F	Q	V	F	G	A	D	A	M	R	G	P	R	G	L	K	A	V	G	P	Y	V	V	T	K	A	M	A	S	G	V	S	A	C	L	A	T	P	F	K	I	H	G
Query Conservation
Alig confidence																					.																					.	.	.	.	.	.	.	.
Template Conservation																					.																					.	.	.	.	.	.	.	.
Template Sequence		L	L	E	V	T	Y	E	A	I	V	D	G	G	I	N	P	D	S	L	.	R	G	T	H	T	G	V	W	V	G	V	S	G	S	E	T	S	E	A	L	.	.	.	.	.	.	.	.	S	R	D	P	E	T	L	V	G	Y	S	M	V	G	C	Q	R	A	M	M	A	N	R	L	S	F	F	F	D	F	R	G
Template Known Secondary structure													T	T			G	G	G	G	.	T	T	S																		.	.	.	.	.	.	.	.	T	S		T	T	T			T							S	T	T											T			S
Template Predicted Secondary structure																					.																					.	.	.	.	.	.	.	.
Template SS confidence
		82	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100		.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120									.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.
		155	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		V	N	Y	S	I	S	S	A	C	A	T	S	A	H	C	I	G	N	A	V	E	Q	I	Q	L	G	K	Q	D	I	V	F	A	G	G	G	E	E	L	C	W	E	M	A	C	E	F	D	A	M	G	A	L	S	T	K	Y	N	D	T	P	E	K	A	S	R	T	Y	D	A	H	R	D	G	F	V	I	A	G	G
Query Conservation
Alig confidence																																																.	.	.	.	.
Template Conservation																																																.	.	.	.	.
Template Sequence		P	S	I	A	L	D	T	A	C	S	S	S	L	M	A	L	Q	N	A	Y	Q	A	I	H	S	G	Q	C	P	A	A	I	V	G	G	I	N	V	L	L	K	P	N	T	S	V	.	.	.	.	.	Q	F	L	R	L	G	M	L	S	P	E	G	T	C	K	A	F	D	T	A	G	N	G	Y	C	R	S	E	G
Template Known Secondary structure									G	G	G															T	T	S		S																		.	.	.	.	.						T		B		T	T	S				T	T	B	T	T				B		B	B
Template Predicted Secondary structure																																																.	.	.	.	.
Template SS confidence
		153	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.						.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.
		235	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.				.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290				.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.
Predicted Secondary structure																																				.	.	.																							.	.	.
Query SS confidence																																				.	.	.																							.	.	.
Query Sequence		G	G	M	V	V	V	E	E	L	E	H	A	L	A	R	G	A	H	I	Y	A	E	I	V	G	Y	G	A	T	S	D	G	A	D	.	.	.	M	V	A	P	S	G	E	G	A	V	R	C	M	K	M	A	M	H	G	V	D	T	.	.	.	P	I	D	Y	L	N	S	H	G	T	S	T	P	V	G	D	V	K
Query Conservation																																				.	.	.																							.	.	.
Alig confidence														.	.	.	.																			.	.	.																							.	.	.
Template Conservation														.	.	.	.
Template Sequence		V	V	A	V	L	L	T	K	K	S	L	A	.	.	.	.	R	R	V	Y	A	T	I	L	N	A	G	T	N	T	D	G	F	K	E	Q	G	V	T	F	P	S	G	D	I	Q	E	Q	L	I	R	S	L	Y	Q	S	A	G	V	A	P	E	S	F	E	Y	I	E	A	H	G	T	G	T	K	V	G	D	P	Q
Template Known Secondary structure										G	G	G		.	.	.	.	S	S		S															T	T		T	T	S																		T			G	G	G												T	T
Template Predicted Secondary structure														.	.	.	.
Template SS confidence
		228	.	230	.	.	.	.	.	.	.	.	.					240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.
		309	310	.	.	.	.	.	.	.	.				.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.						370	.	.	.	.	.	.	.	.	.	380
Predicted Secondary structure												.	.	.																																																				.	.	.	.	.
Query SS confidence												.	.	.																																																				.	.	.	.	.
Query Sequence		E	L	A	A	I	R	E	V	F	G	.	.	.	D	K	S	P	A	I	S	A	T	K	A	M	T	G	H	S	L	G	A	A	G	V	Q	E	A	I	Y	S	L	L	M	L	E	H	G	F	I	A	P	S	I	N	I	E	E	L	D	E	Q	A	A	.	.	.	.	.	G	L	N	I	V	T	E	T	T	D	R
Query Conservation												.	.	.																																																				.	.	.	.	.
Alig confidence												.	.	.																																																				.	.	.	.	.
Template Conservation
Template Sequence		E	L	N	G	I	T	R	A	L	C	A	T	R	Q	E	P	L	L	I	G	S	T	K	S	N	M	G	H	P	E	P	A	S	G	L	A	A	L	A	K	V	L	L	S	L	E	H	G	L	W	A	P	N	L	H	F	H	S	P	N	P	E	I	P	A	L	L	D	G	R	L	Q	V	V	D	Q	P	L	P	V
Template Known Secondary structure											S	S	S		S	S							T						B		G	G	G																T	B					S	S			S	B		T	T							T	S						S			B
Template Predicted Secondary structure
Template SS confidence
		304	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.
		381	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		E	L	T	T	V	M	S	N	S	F	G	F	G	G	T	N	A	T	L	V	M	R	K	L	K	D
Query Conservation
Alig confidence
Template Conservation
Template Sequence		R	G	G	N	V	G	I	N	S	F	G	F	G	G	S	N	V	H	I	I	L	R	P	N	T	Q
Template Known Secondary structure			S										T	T	S
Template Predicted Secondary structure
Template SS confidence
		384	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.