Job Description P0A953 Confidence 99.37% Date Thu Jan 5 11:09:24 GMT 2012 Rank 86 Aligned Residues 260 % Identity 18% Template c2p8uB_ PDB info PDB header:transferase Chain: B: PDB Molecule:hydroxymethylglutaryl-coa synthase, cytoplasmic; PDBTitle: crystal structure of human 3-hydroxy-3-methylglutaryl coa synthase i Resolution 2.00 Å

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		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.		.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.
Predicted Secondary structure																		.
Query SS confidence																		.
Query Sequence		M	K	R	A	V	I	T	G	L	G	I	V	S	S	I	G	.	N	N	Q	Q	E	V	L	A	S	L	R	E	G	R	S	G	I	T	F	S	Q	E	L	K	D	S	G	M	R	S	H	V	W	G	N	V	K	L	D	T	T	G	L	I	D	R	K	V	V	R	F	M	S	D	A	S	I	Y	A	F	L	S	M
Query Conservation																		.
Alig confidence				.														.											.	.	.	.	.																												.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation				.																									.	.	.	.	.																												.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		M	D	.	V	G	I	V	A	L	E	I	Y	F	P	S	Q	Y	V	D	Q	A	E	L	E	K	Y	D	.	.	.	.	.	G	V	D	A	G	K	Y	T	I	G	L	G	Q	A	K	M	G	F	C	T	D	R	E	D	I	N	S	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	L	C	M	T	V	V
Template Known Secondary structure				.												S													.	.	.	.	.	T			T	T																T	T						.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Predicted Secondary structure				.																									.	.	.	.	.																												.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		15	.		.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40						.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.																.	.	70	.	.	.
		80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.			.	.	.
Predicted Secondary structure																																																																													.	.
Query SS confidence																																																																													.	.
Query Sequence		E	Q	A	I	A	D	A	G	L	S	P	E	A	Y	Q	N	N	P	R	V	G	L	I	A	G	S	G	G	G	S	P	R	F	Q	V	F	G	A	D	A	M	R	G	P	R	G	L	K	A	V	G	P	Y	V	V	T	K	A	M	A	S	G	V	S	A	C	L	A	T	P	F	K	I	H	G	.	.	V	N	Y
Query Conservation																																																																													.	.
Alig confidence																		.	.	.	.	.											.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																		.	.
Template Conservation																		.	.	.	.	.											.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		Q	N	L	M	E	R	N	N	L	S	Y	D	C	I	G	R	.	.	.	.	.	L	E	V	G	T	E	T	I	I	D	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	K	S	K	S	V	K	T	N	L	M	Q	L	F	E	E	S	G	N	T	D	I	E
Template Known Secondary structure								T	T			G	G	G				.	.	.	.	.						S			S		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	S	S	S							G	G	G	T	G	G	G	T					B
Template Predicted Secondary structure																		.	.	.	.	.											.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		74	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.						90	.	.	.	.	.	.	.	.	.																												100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.
		158	.	160	.		.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.			.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.
Predicted Secondary structure						.																							.	.
Query SS confidence						.																							.	.
Query Sequence		S	I	S	S	.	A	C	A	T	S	A	H	C	I	G	N	A	V	E	Q	I	Q	L	G	K	Q	D	.	.	I	V	F	A	G	G	G	E	E	L	C	W	E	M	A	C	E	F	D	A	M	G	A	L	S	T	K	Y	N	D	T	P	E	K	A	S	R	T	Y	D	A	H	R	D	G	F	V	I	A	G	G
Query Conservation						.																							.	.
Alig confidence						.																							.	.												.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																																										.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		G	I	D	T	T	N	A	Y	G	G	T	A	A	V	F	N	A	V	N	W	I	E	S	S	S	W	D	G	R	Y	A	L	V	V	A	G	D	I	A	V	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	Y	A	T	G	N	A	R	P	T	G	G	V	G
Template Known Secondary structure																								S	T	T			S													.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.			S	S	T	T	G	G	G
Template Predicted Secondary structure																																										.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		122	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.																												.	.	.	.	.	.	.	.	170	.	.	.	.
		235	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.		.	.	.	.	.	.	270	.	.	.	.																													.	.	.	.	.	280	.	.	.	.	.
Predicted Secondary structure																															.												.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence																															.												.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		G	G	M	V	V	V	E	E	L	E	H	A	L	A	R	G	A	H	I	Y	A	E	I	V	G	Y	G	A	T	.	S	D	G	A	D	M	V	A	P	S	G	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	E	G	A	V	R	C	M	K	M	A	M
Query Conservation																															.												.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence										.	.	.	.	.	.	.															.												.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation										.	.	.	.	.	.	.
Template Sequence		A	V	A	L	L	I	G	P	.	.	.	.	.	.	.	N	A	P	L	I	F	E	R	G	L	R	G	T	H	M	Q	H	A	Y	D	F	Y	K	P	D	M	L	S	E	Y	P	I	V	D	G	K	L	S	I	Q	C	Y	L	S	A	L	D	R	C	Y	S	V	Y	C	K	K	I	H	A	Q	W	Q	K	E	G
Template Known Secondary structure									S	.	.	.	.	.	.	.	S		S					T	T											S						T	T		S	S																																		T	T
Template Predicted Secondary structure										.	.	.	.	.	.	.
Template SS confidence
		176	.	.	.	180	.	.	.								.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.
		286	.	.	.	290				.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.																																													.	.	.	.	.
Predicted Secondary structure							.	.	.																								.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence							.	.	.																								.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		H	G	V	D	T	.	.	.	P	I	D	Y	L	N	S	H	G	T	S	T	P	V	G	D	V	K	E	L	A	A	I	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	R	E	V	F	G
Query Conservation							.	.	.																								.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence							.	.	.																								.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		N	D	K	D	F	T	L	N	D	F	G	F	M	I	F	H	S	P	Y	C	K	L	V	Q	K	S	L	A	R	M	L	L	N	D	F	L	N	D	Q	N	R	D	K	N	S	I	Y	S	G	L	E	A	F	G	D	V	K	L	E	D	T	Y	F	D	R	D	V	E	K	A	F	M	K	A	S	S	E	L	F	S
Template Known Secondary structure								G	G	G		S							S	S																				T	T	G	G	G		G	G	G	T	T		G	G	G	T	T			G	G	G		T	T												T
Template Predicted Secondary structure
Template SS confidence
		249	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.
		319	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		D	K	S	P	A	I	S	A	T	K	A	M	T	G	H	S	L	G	A	A	G	V	Q	E	A	I	Y	S	L
Query Conservation
Alig confidence
Template Conservation
Template Sequence		Q	K	T	K	A	S	L	L	V	S	N	Q	N	G	N	M	Y	T	S	S	V	Y	G	S	L	A	S	V	L
Template Known Secondary structure				T	T	G	G	G										G	G	G
Template Predicted Secondary structure
Template SS confidence
		329	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.

No model constructed - rank, confidence too low

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
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