|   |
312 | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | |
|
|
|
|
|
|
|
. | . | . | . | |
|
|
|
|
. | . | . | . | 350 | . | . | . | . | . | . | . | |
|
|
. | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . |
Predicted Secondary structure |   |
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |  |  |  |  | . | . | . | . | . |  |  |
|
|
|
|
|
|
|  |  |  | . | . | . |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Q | L | T | V | K | G | P | Q | V | A | E | Q | P | A | A | V | P | G | N | W | R | D | D | F | D | A | S | S | L | D | . |
. |
. |
. |
. |
. |
. |
. |
P | E | L | Q | . |
. |
. |
. |
. |
T | L | R | I | P | F | D | D | T | L | G | S | . |
. |
. |
L | T | A | R | P | G | F | L | R | L | Y | G | N | D | S | L | N | S |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |   |   |
|   | . | . | . | . | . | . | . | . |   |   |
|   | . | . | . | . | . |   |   |   |   |
|   |
|   |   |   |   |
| . | . | . |
|   |   |   |   |
|   |
|
|
|   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
| . | . | . | . | . |
|
|
|
|
| . |
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |
|   |   |
|   |   |   |   |   |
|   |
|   |   |   |   |
|
|
|
|
|
|   |   |
|
|   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   | . |   |   |   |   |   |   |   |   |
|
|   |
|   |
|
|   |
|   |
|   |   |   |   |   |   |   |   |
Template Sequence |   |
G | I | P | V | P | A | N | P | G | N | G | M | T | W | Q | L | Q | D | N | V | S | D | S | F | N | Y | T | S | S | E | G | N | R | P | T | A | F | T | S | K | W | K | P | S | Y | I | N | G | W | T | G | P | . |
G | S | T | I | F | N | A | P | Q | A | W | T | N | G | S | Q | L | A | I | Q | A | Q | P | A | G | N | G |
Template Known Secondary structure |   |
T |
|
|
| S | S |
|
|
| T | T |  |  |  |  |  |
| G | G | G |
| B |
|
|
| S |  |  | B | T | T | B |
|
|  |  |  |  | T | T |  |  | S | S |
| S | S | S |
|
|
| S | . | T | T |  |  |  |
| G | G | G |  |  |  |  | S | S |
|  |  |  |  |  |  |  |  |  | T | T |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|  |  |  |
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
25 | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | |
. | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . |
  |
  |   |
376 | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | |
. | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | |
|
|
|
|
|
|
. | . | . | . | . | . | . | 440 | |
|
|
|
|
|
|
Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  | . |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  | . | . | . | . | . | . | . |  |  |  |  |  |  |  |
| . | . | . | . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
Query Sequence |   |
T | F | T | Q | S | T | V | A | R | R | W | Q | H | F | A | F | . |
R | A | E | T | R | M | E | F | S | P | V | H | F | Q | Q | S | A | G | L | T | C | Y | Y | N | S | K | N | W | S | Y | C | F | V | D | Y | E | E | G | Q | G | R | . |
. |
. |
. |
. |
. |
. |
T | I | K | V | I | Q | L | D | . |
. |
. |
. |
. |
. |
. |
Query Conservation |   |
  |   |   |   |   |   |
|   |
|
|   |   |   |   |   |   | . |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |
|
|
|   |
|   |   |
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
Template Conservation |   |
  |   |   |
|
|   |
|   |
|   |   |   |   |   |
|
|
|   |   |
|   |
|   |
|   |   | . | . |   |   |
|   |   |
|
|
|
|   |   |   |   |   |   |   | . |   |
|
|
|
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
K | S | Y | N | G | I | I | T | S | K | N | K | I | Q | Y | P | V | Y | M | E | I | K | A | K | I | M | . |
. |
D | Q | V | L | A | N | A | F | W | T | L | T | D | D | E | T | . |
Q | E | I | D | I | M | E | G | Y | G | S | D | R | G | G | T | W | F | A | Q | R | M | H | L | S | H | H | T | F | I | R | N | P | F | T |
Template Known Secondary structure |   |
 |  |  |  |
|  |  |  |  | S | S |
| B |
| S | S |  |  |  |  |  |  |  |  |
|
| . | . | S | S | S | S |  |  |  |  |  |  |  |
| T | T | S |
| . |  |  |  |  |  |  |  |  |  |
|
| G | G | G |
|  |  |  |  | T |  |  |  |  |  |  |  |  |  |  | T | T | T | T |  |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
| . | . |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
| . |
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
104 | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | |
|
130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | |
. | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 |
  |
  |   |
|
441 | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | |
. | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
. |
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  | . |  |  |
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
Query SS confidence |   |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
H | N | V | P | S | W | P | L | H | E | Q | P | I | P | V | P | E | H | A | E | S | V | W | L | R | V | D | . |
V | D | T | L | V | Y | R | Y | S | Y | S | F | D | G | E | T | W | H | T | V | P | V | T | Y | E | A | W | K | L | S | D | D | Y | I | G | G | R | G | F | F | T | G | A | F | V | G | L | H | C | E | D |
Query Conservation |   |
. |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|   | . |   |   |   |   |   |   |   |
|   |
|
|   |
|
|   |   |
|   |   |
|
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |   |
|
|
|
|   |   |
Alig confidence |   |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |
|
|
|   |
|
|   |   |
|   |   |
| . | . |
|
|
|   |   |   |   |
|   | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |
|
|
|
|   |   |
Template Sequence |   |
D | Y | Q | P | M | G | D | A | T | W | Y | Y | N | G | G | T | P | W | R | S | A | Y | H | R | Y | G | C | Y | W | K | D | P | F | T | L | E | Y | Y | . |
. |
I | D | G | V | K | V | R | T | V | . |
. |
. |
. |
T | R | A | E | I | D | P | N | N | H | L | G | G | T | G | L | N | Q | A | T | N | I | I | I | D | C | E |
Template Known Secondary structure |   |
 |  |
|
|
|
| G | G | G |  |  |  |
| T | T |
|
| G | G | G | S |
|  |  |  |  |  |  |  |  |  | T | T |  |  |  |  |  | . | . |  | T | T |  |  |  |  |  |  | . | . | . | . |
|  |  |  |  |
| T | T |
| T | T | T | T |
|
| S |
| S |
| B |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  | . | . |  |
|
|  |  |  |  |  |  | . | . | . | . |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
181 | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | |
|
. | 220 | . | . | . | . | . | . | . | |
|
|
|
. | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . |
  |
  |   |
519 | 520 | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | 530 | . | . | |
. | . | . | . |
Predicted Secondary structure |   |
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|  |  |  |  |  |  |  |  |  | . |  |  |  |
|
Query SS confidence |   |
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
Query Sequence |   |
I | S | G | D | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
G | C | Y | A | D | F | D | Y | F | T | . |
Y | E | P | V |
Query Conservation |   |
  |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |
|
|
|
|   |
|   | . |   |   |   |   |
Alig confidence |   |
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
Template Conservation |   |
  |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|
|
|
|
|
|   |   |
Template Sequence |   |
N | Q | T | D | W | R | P | A | A | T | Q | E | E | L | A | D | D | S | K | N | I | F | W | V | D | W | I | R | V | Y | K | P | V |
Template Known Secondary structure |   |
|
| T | T | T | S |
|
|
|
|  |  |  |  |  |
| T | T | T | S |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
255 | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . |
  |