|   |
1 | . | . | . | . | . | . | . | . | 10 | . | . | . | |
|
. | . | . | . | . | . | 20 | . | . | |
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | 30 | |
. | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | |
|
|
|
. | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . |
Predicted Secondary structure |   |
|
|  |  |
|
|
|
|
|
|
|
|
| . | . |
|
|  |  |  |  |  |
|
| . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |
| . |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
| . | . | . | . |
|  |  |  |
|
|  |  |
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
M | E | I | T | N | P | I | L | T | G | F | N | P | . |
. |
D | P | S | L | C | R | Q | G | E | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
D | Y | Y | I | A | T | S | T | . |
F | E | W | F | P | G | V | R | I | Y | H | S | R | D | L | K | N | . |
. |
. |
. |
W | S | L | V | S | T | P | L | D | R | V | S | M | L | D |
Query Conservation |   |
  |   |   |   |
|
|
|   |   |
|   |   |
| . | . |
|
|   |
|
|
|   |   |
| . | . | . | . | . | . | . | . | . | . | . |   |
|
|   |   |   |
|
| . |   |   |   |   |
|
|   |   |
|   |   |
|   |
|
|
|   | . | . | . | . |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |
|   |   |
|   |   |
|
|
|
|
|
|
|
|
|
|
|
|   |   |
|   |   |   |   |   |   |
|
|   |
|
|
|
|
|   |   |   |
|   |   |   |   |
|
|   |
|   |   |   |
|   |   |   |
|   |   |   |   |   |   |
|   |   |   |
|   |
|
|   |   |   |   |   |   |   |
Template Sequence |   |
S | T | I | K | N | I | S | S | A | K | G | L | D | V | W | D | S | W | P | L | Q | N | A | D | G | T | V | A | N | Y | H | G | Y | H | I | V | F | A | L | A | G | D | P | K | N | A | D | D | T | S | I | Y | M | F | Y | Q | K | V | G | E | T | S | I | D | S | W | K | N | A | G | R | V | F | K | D | S | D | K | F | D |
Template Known Secondary structure |   |
G | G |
|
|
|
| G | G | G | T | T |
|  |  |  |  |  |  |  |  |  |
| T | T | S | S | B |
|
| B | T | T |  |  |  |  |  |  |  |  |  |
| T | T |
| T | T |
|
|  |  |  |  |  |  |  |  | T | T |
|
| S | G | G | G |
|  |  |  |  |  | S |
|
| T | T |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|  |  |  |
|
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
71 | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 |
  |
  |   |
63 | . | . | . | . | . | . | 70 | . | |
|
. | . | . | . | . | . | . | . | |
80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | |
|
|
. | 100 | . | . | . | . | . | . | . | . | . | 110 | |
|
|
. | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | |
|
|
|
|
|
|
|
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
| . | . |  |  |
|  |  |  |  |  | . |  |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
| . | . | . |
|
|  |  |  |  |  |  |  |  |
|
| . | . | . |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
| . | . | . | . | . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
Query Sequence |   |
M | K | G | N | P | D | S | G | G | . |
. |
I | W | A | P | C | L | S | Y | . |
A | D | G | K | F | W | L | L | Y | T | D | V | K | I | V | D | S | P | W | . |
. |
. |
K | N | G | R | N | F | L | V | T | A | P | S | . |
. |
. |
I | E | G | P | W | S | E | P | I | P | M | G | N | G | G | . |
. |
. |
. |
. |
. |
. |
. |
Query Conservation |   |
  |   |   |   |   |   |   |   |
| . | . |   |
|
|
|   |
|   |   | . |   |   |
|   |
|
|
|   |   |
|   |   |   |   |   |   |   |   |   | . | . | . |   |   |   |   |   |   |
|   |   |
|   |   | . | . | . |
|   |
|
|
|   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
Template Conservation |   |
  |   |   |   |   |   |   |   |   |
|   |
|
|
|
|
|
|
|   |   |   |
|
|   |
|   |
|
|
|
|   |   |   |   |   |   |   |   |   |
|   |
|
|   |
|   |   |   |
|   |   |
|   |
|
|
|   |   |   |
|   |   |   |   |   |
|
|
|   |   |
|
|   |   |
|
|
|   |   |
|
Template Sequence |   |
A | N | D | S | I | L | K | D | Q | T | Q | E | W | S | G | S | A | T | F | T | S | D | G | K | I | R | L | F | Y | T | D | F | S | G | K | H | Y | G | K | Q | T | L | T | T | A | Q | V | N | V | S | A | S | D | S | S | L | N | I | N | G | V | E | D | Y | K | S | I | F | D | G | D | G | K | T | Y | Q | N | V | Q | Q |
Template Known Secondary structure |   |
T | T |
| T | T | G | G | G |
|
|  |  |  |  |  |  |  |  |  |
| T | T | S |
|  |  |  |  |  |  |  |  |  | T | T | T | T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |
| S | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| S | S | S | B |
|
|  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |
|
|
|
|  |  |  |
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
151 | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 |
  |
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
126 | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. |
Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
Query SS confidence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
Query Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
F | D | P | S | L | F | H | D | D | D | G | R | K | Y | Y | I | Y | R | P | W | G | P | R | H | H | S | N | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
P |
Query Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |
|
|   |   |
|   |
|   |
|
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|   |
|
|
|
| . |   |
|   |   |
|
|   |
|
|
|
|
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
Template Sequence |   |
F | I | D | E | G | N | Y | S | S | G | D | N | H | T | L | R | A | P | H | Y | V | E | D | . |
K | G | H | K | Y | L | V | F | E | A | N | T | G | T | E | D | G | Y | Q | G | E | E | S | L | F | N | K | A | Y | Y | G | K | S | T | S | F | F | R | Q | E | S | Q | K | L | L | Q | S | D | K | K | R | T | A | E | L | A |
Template Known Secondary structure |   |
 |  |  |  | T | G | G | G | G | T |
|
|
|
|
|  |  |  |  |  |  |  |  | . | T | T |  |  |  |  |  |  |  |  |  | B |
| T | T | S |
|
| S | S | G | G | G | G | G | B | G | G | G | T |
| S |
|  |  |  |  |  |  |  |  |  |  |  |  |  | S | T | T |  |  |  |  |  |  |
|
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|  |  |  |  |
| . |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |
|
|
|
|
|
|
|  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
231 | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | |
. | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . |
  |
  |   |
154 | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | |
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
H | N | T | I | V | L | Q | A | F | D | P | Q | T | G | T | L | S | P | E | R | K | T | L | F | T | G | T | P | L | C | Y | T | E | G | A | H | L | Y | R | H | A | G | W | Y | Y | L | M | A | A | E | G | G | T | S | Y | E | H | . |
. |
. |
. |
. |
. |
. |
. |
A | V | V | V | L | R | S | K | N | I | D | G | P | Y | E |
Query Conservation |   |
  |   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|
|
|   |
|   |
|   |   |
|   |
|
|
|   |   |
|   |
|
|   |   |   |   |   | . | . | . | . | . | . | . | . |   |   |   |   |   |
|
|   |   |   |   |
|
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|   |
|
|
|   |   |
|
|   |
|   |   |   |
|
|
|   |   |
|
|
|   |
|   |   |
|   |
|
|
|
|
|
|   |
|
|   |   |
|
|
|
|
|
|
|
|   |
|
|   |   |   |   |
|   |   |   |   |   |
|   |   |
|   |
|   |
|   |
|
|
|
|
|   |
|
|
|   |
Template Sequence |   |
N | G | A | L | G | M | I | E | L | N | D | D | Y | T | L | K | K | V | M | K | P | L | I | A | S | N | T | V | T | D | E | I | E | R | A | N | V | F | K | M | N | G | K | W | Y | L | F | T | D | S | R | G | S | K | M | T | I | D | G | I | T | S | N | D | I | Y | M | L | G | Y | V | S | N | S | L | T | G | P | Y | K |
Template Known Secondary structure |   |
|  |  |  |  |  |  |  |  |
| T | T | S | S |  |  |  |  |  |  |  |  |  |  |
| T | T | T |
| S |
|
|  |  |  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |  |  | G | G | G |
|
|
| T | T |
|
| T | T |
|  |  |  |  |  |  |  |  | S | S | T | T |
|
|
|  |
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . |
  |
  |   |
226 | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | H | P | D | V | T | M | M | T | S | W | H | L | P | E | N | P | L | Q | K | S |
Query Conservation |   |
  |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|
|
|
|
|
|
|
|   |   |   |   |
|   |   |   |   |   |   |
|
Template Sequence |   |
P | L | N | K | T | G | L | V | L | K | M | D | L | D | P | N | D | V | T | F | T |
Template Known Secondary structure |   |
 | G | G | G | T | S |  |  |  |  |  |
|
|
| T | T |
| T | T |
|  |
Template Predicted Secondary structure |   |
 |
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 |
  |