|   |
1 | . | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | |
|
|
. | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
| . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |
|
|  |  |  |  |
|
|
|
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
M | T | R | L | T | L | A | L | D | V | M | G | G | D | F | G | . |
. |
. |
P | S | V | T | V | P | A | A | L | Q | A | L | N | S | N | S | Q | L | T | L | L | L | V | G | N | S | D | A | I | T | P | L | L | A | K | A | D | F | E | Q | R | S | R | L | Q | I | I | P | A | Q | S | V | I | A | S | D | A | R | P | S | Q |
Query Conservation |   |
|   |   |   |   |
|
|
|
|
|
|
|
|
|   |   | . | . | . |
|   |   |   |
|   |
|
|   |   |
|
|   |   |   |   |   |   |   |
|
|
|
|
|   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |
|
|   |
|   |   |   |
|   |
|   |   |   |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
| . | . | . |
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |   |   |
|
|
|
|   | . | . |
|
|
|
|
|
|
|
|
|
|
|   |
| . | . | . | . |
|
|   |   |   |   |   |   |   |   |
|
|
|
|
|   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   | . | . |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
V | K | T | Q | R | V | V | I | T | P | . |
. |
G | E | P | A | G | I | G | P | D | L | V | V | Q | . |
. |
. |
. |
L | A | Q | R | E | W | P | V | E | L | V | V | C | A | D | A | T | L | L | T | N | R | A | A | X | L | G | L | P | L | T | . |
. |
L | R | P | Y | S | P | N | S | P | A | Q | P | Q | T | A | G | T | L |
Template Known Secondary structure |   |
|
|
|
|  |  |  |  |  |
| . | . |
| S | T | T | S | S |  |  |  |  |  |  |  | . | . | . | . |  | T | T | S |
|
| S | S |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  | T | T |
|
|
|  | . | . |  |  |  |
|
| T | T | S |
|
|
|
|
|
| T | T |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |
| . | . |
|
|
|
|
|
|
|  |  |  |  |  |  | . | . | . | . |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
2 | . | . | . | . | . | . | . | 10 | . | |
|
. | . | . | . | . | . | . | . | 20 | . | . | . | . | |
|
|
|
. | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | |
|
. | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . |
  |
  |   |
78 | . | 80 | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
. | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . |
Predicted Secondary structure |   |
 |  |  |  |
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | I | R | A | S | R | G | S | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
S | M | R | V | A | L | E | L | V | K | E | G | R | A | Q | A | C | V | S | A | G | N | T | G | A | L | M | G | L | A | K | L | . |
. |
. |
. |
. |
. |
. |
L | L | K | P | L | E | G | I | E | R | P | A | L | V | T |
Query Conservation |   |
|
|
|   |
|
|   |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|   |   |
|   |   |
|
|
|   |
|   |
|
|
|   |
|
|
|
|
|
|
|
|   |
|   |   |
|   |   | . | . | . | . | . | . | . |
|
|
|   |
|
|
|
|   |
|
|
|   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |
|   |   |   |
|   |   |   |   |   |
|
|   |   |
|
|   |
|
|   |   |
|   |
|
|
|
|
|
|
|
|   |
|
|
|   |   |   |   |
|
|   |   |   |   |
|
|
|
|   |
|   |   |   |   |
|   |   |   |   |   |
|   |   |
Template Sequence |   |
T | L | L | P | V | A | L | R | A | P | V | T | A | G | Q | L | A | V | E | N | G | H | Y | V | V | E | T | L | A | R | A | C | D | G | C | L | N | G | E | F | A | A | L | I | T | G | P | V | H | K | G | V | I | N | D | A | G | I | P | F | T | G | H | T | E | F | F | E | E | R | S | Q | A | K | K | V | V | X | X | L |
Template Known Secondary structure |   |
 |  |  |  |
|
|
| S | S |
|
| B | T | T | B |
|
| T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | S |
| S |  |  |  |  |
|
|
|
|  |  |  |  |  |  | T | T |
|
|
|
|
|  |  |  |  |  |  |  |  | T | T |
| S |
|
|  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
74 | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . |
  |
  |   |
133 | . | . | . | . | . | . | |
|
|
|
140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | |
|
|
|
. | . | . | . | 190 | . | . | . | |
|
|
. | . | . | . | . | . | 200 | . |
Predicted Secondary structure |   |
 |  |  |  |
|
|
| . | . | . | . |
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
| . | . | . | . |
|
|
|
|
|
|
|
| . | . | . |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
Query Sequence |   |
V | L | P | H | Q | Q | K | . |
. |
. |
. |
G | K | T | V | V | L | D | L | G | A | N | V | D | C | D | S | T | M | L | V | Q | F | A | I | M | G | S | V | L | A | E | E | V | V | E | I | P | N | P | R | V | A | L | L | N | I | . |
. |
. |
. |
G | E | E | E | V | K | G | L | . |
. |
. |
D | S | I | R | D | A | S | A |
Query Conservation |   |
  |
|
|
|   |   |   | . | . | . | . |   |   |   |
|
|   |
|   |
|
|
|
|
|   |   |
|
|   |
|   |
|
|
|
|
|
|
|   |   |
|
|   |
|
|
|
|
|   |
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|   |   |
|
|   | . | . | . |   |   |
|
|
|
|   |   |
Alig confidence |   |
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |
|   |
|   |   |   |
|   |
|
|   |
|   |
|
|   |   |   |
| . | . |
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|
|
|
|
|
|   |
|
|
|
|
|
|
|   |
|   |   |
|   |
|
|   |   |   |
|   |
|
|
|   |
Template Sequence |   |
A | T | E | E | L | R | V | A | L | A | T | T | H | L | P | L | R | D | I | A | D | A | I | . |
. |
T | P | A | L | L | H | E | V | I | A | I | L | H | H | D | L | R | T | K | F | G | I | A | E | P | R | I | L | V | C | G | L | N | P | H | A | G | E | G | G | H | X | G | T | E | E | I | D | T | I | I | P | V | L | N |
Template Known Secondary structure |   |
 | S | S | S |
|  |  |  |  | S | S |
| S | S |
| G | G | G |  |  |  |  |
| . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
| S | S |
|  |  |  |  |  |
| S | S | G | G | G | G | G | G | G | T | T |
| S |  |  |  |  | T |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
| . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
154 | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | |
|
. | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . |
  |
  |   |
202 | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | |
|
|
|
. | . | . | . | . | . | . | 230 | . | . | . | |
. | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|  |  |  |  |  |
|  |  |  |
|
|
| . | . | . | . |
|
|
|
|  |  |  |  |
|
|
| . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | L | K | T | I | P | S | I | N | Y | I | G | Y | L | E | A | N | E | L | L | T | . |
. |
. |
. |
G | K | T | D | V | L | V | C | D | G | F | . |
T | G | N | V | T | L | K | T | M | E | G | V | V | R | M | F | L | S | L | L | K | S | Q | G | E | G | K | K | R | S | W | W | L | L | L | L | K | R | W | L | Q | K | S |
Query Conservation |   |
|
|   |   |   |   |   |   |
|
|   |
|
|
|
|
|   |
|
|   |   | . | . | . | . |
|   |   |
|
|
|
|   |
|
|
| . |
|
|
|
|   |
|
|   |   |
|
|   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
Template Conservation |   |
  |
|   |   |   | . |
|
|   |   |   |
|
|   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |
|   |
|
|   |
|
|
|
|
|
|   |
|   |   |
|   |
|   | . | . | . | . | . | . | . | . | . | . | . | . | . |
|   |   |
|
|
| . | . | . | . | . | . | . | . | . | . |   |
|
|
|
Template Sequence |   |
E | L | R | A | Q | . |
G | X | K | L | N | G | P | L | P | A | D | T | L | F | Q | P | K | Y | L | D | N | A | D | A | V | L | A | X | Y | H | D | Q | G | L | P | V | L | K | Y | Q | G | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
F | G | R | G | V | N | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
I | T | L | G |
Template Known Secondary structure |   |
 |  |  |  | T | . | T |
|  |  |  |  |  |  |
|  |  |  |  | S | S |  |  |  |  | T | T |
| S |  |  |  |  | S | S |  |  |  |  |  |  |  |  |  | T | T |
| . | . | . | . | . | . | . | . | . | . | . | . | . | S | S | S |
|  |  | . | . | . | . | . | . | . | . | . | . |  |  |  | S |
Template Predicted Secondary structure |   |
 |  |  |  |
| . |
|
|
|  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|  |  |  | . | . | . | . | . | . | . | . | . | . |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
232 | . | . | . | . | |
. | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
. | . | 280 | . | . | . | |
|
|
|
|
|
|
|
|
|
. | . | . | . |
  |
  |   |
277 | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|  |  |  |  |
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | T | R | R | F | S | H | L | N | P | D | Q | Y | N | G | A | C | L | L | G | L | R | G | T | V | I | K | S | H | G | A | A | N | Q | R | A | F | A | V | A | I | E | Q | A | V | Q | A | V | Q | R |
Query Conservation |   |
|   |   |   |   |   |   |   |
|   |   |   |   |
|
|
|   |
|
|
|
|   |
|   |
|
|
|   |
|
|   |
|   |   |   |
|   |   |   |
|
|   |   |
|   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
| . | . |
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|   |
|
|
|
|   |
| . | . | . |
|
|
|
| . | . |   |
|
|
|
| . | . | . | . | . |   |
|   |
|
|   |   |
|   |   |   |
|
|   |   |
|   |   |   |   |   |
|
Template Sequence |   |
L | P | F | I | R | T | S | V | D | . |
. |
. |
H | G | T | A | . |
. |
L | E | L | A | G | . |
. |
. |
. |
. |
R | G | K | A | D | V | G | S | F | I | T | A | L | N | L | A | I | K | X | I | V | N |
Template Known Secondary structure |   |
S | S | S |  |  |  |  |
| S | . | . | . | S |
|
|
| . | . | G | G | G | T | T | . | . | . | . | . | S | S |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|  |  |  |  |
|
|
| . | . | . |
|
|
|  | . | . |  |
|
|
|
| . | . | . | . | . |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
288 | . | 290 | . | . | . | . | . | . | |
|
|
. | . | . | 300 | |
|
. | . | . | . | . | |
|
|
|
|
. | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . |
  |