Job Description P25550 Confidence 86.16% Date Thu Jan 5 11:42:07 GMT 2012 Rank 18 Aligned Residues 149 % Identity 8% Template c2cw6B_ PDB info PDB header:lyase Chain: B: PDB Molecule:hydroxymethylglutaryl-coa lyase, mitochondrial; PDBTitle: crystal structure of human hmg-coa lyase: insights into2 catalysis and the molecular basis for3 hydroxymethylglutaric aciduria Resolution 2.10 Å

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		41	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Predicted Secondary structure
Query SS confidence
Query Sequence		P	V	T	H	M	D	D	D	T	L	E	A	Y	V	R	H	Y	I	A	A	S	E	P	Q	N	E	V	A	F	T	W	Q	G	G	E	P	T	L	L	G	L	A	F	Y	R	R	A	V	A	L	Q	A	K	Y	G	A	G	R	K	I	S	N	S	F	Q	T	N	G	V	L	L	D	D	E	W	C	A	F	L	A
Query Conservation
Alig confidence																							.	.																		.	.	.																								.	.	.	.
Template Conservation																							.	.																		.	.	.																								.	.	.	.
Template Sequence		E	K	N	I	V	S	T	P	V	K	I	K	L	I	D	M	L	S	E	A	G	.	.	L	S	V	I	E	T	T	S	F	V	S	P	K	W	V	P	Q	.	.	.	M	G	D	H	T	E	V	L	K	G	I	Q	K	F	P	G	I	N	Y	P	V	L	T	.	.	.	.	P	N	L	K	G	F	E	A	A	V
Template Known Secondary structure			S	S																	T	T	.	.		S										T	T	T		G	G	.	.	.	G	T	T								S				T	T		B						.	.	.	.		S
Template Predicted Secondary structure																							.	.																		.	.	.																								.	.	.	.
Template SS confidence
		47	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.			.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.				.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.					.	.	110	.	.	.	.	.	.	.
		121	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.								.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.
Predicted Secondary structure																																																								.	.	.	.	.	.	.
Query SS confidence																																																								.	.	.	.	.	.	.
Query Sequence		E	H	H	F	L	V	G	L	S	L	D	G	P	P	E	I	H	N	Q	Y	R	V	T	K	G	G	R	P	T	H	K	L	V	M	R	A	L	T	L	L	Q	K	H	H	V	D	Y	N	V	L	V	C	V	N	.	.	.	.	.	.	.	R	T	S	A	Q	Q	P	L	Q	V	Y	D	F	L	C	D	A	G	V
Query Conservation																																																								.	.	.	.	.	.	.
Alig confidence																																																								.	.	.	.	.	.	.
Template Conservation
Template Sequence		A	A	G	A	K	E	V	V	I	F	G	A	A	S	E	L	F	T	K	K	N	I	N	C	S	I	E	E	S	F	Q	R	F	D	A	I	L	K	A	A	Q	S	A	N	I	S	V	R	G	Y	V	S	C	A	L	G	C	P	Y	E	G	K	I	S	P	A	K	V	A	E	V	T	K	K	F	Y	S	M	G	C
Template Known Secondary structure			T	T		S								S									T	S	S		T	T	T															T	T									S	T	T		B	T	T	T	B	S																T	T
Template Predicted Secondary structure
Template SS confidence
		118	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.
		194	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		E	F	I	Q	F
Query Conservation
Alig confidence
Template Conservation
Template Sequence		Y	E	I	S	L
Template Known Secondary structure		S
Template Predicted Secondary structure
Template SS confidence
		198	.	200	.	.

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
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