|   |
107 | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | P | A | P | K | E | D | A | L | T | V | V | G | D | W | L | G | D | A | R | E | N | D | V | F | E | H | A | G | A | R | D | V | I | R | R | E | D | F | A | K | T | G | A | T | T | M | R | E | V | L | N | R | I | P | G | V | S | A | P | E | N | N | G | T | G | S | H | D | L | A | M | N | F | G | I | R | G | L | N |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|
|
|
|   |
|   |
|   |   |   |   |   |   |   |
|   |
|   |
|   |   |   |
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |
|   |   |   |   |   |   |   |   |
|   |
|
|   |
|
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |
|   |   |
|
|
|
|   |
|   |   |   |   |   |   |   |   | . | . | . | . | . |   |
|   |
|
|
|   |   |
Template Sequence |   |
T | I | T | E | D | S | G | S | Y | T | P | G | T | I | A | T | A | T | R | L | V | L | T | P | R | E | T | P | Q | S | I | T | V | V | T | R | Q | N | X | D | D | F | G | L | N | N | I | D | D | V | X | R | H | T | P | G | I | T | V | S | A | Y | D | T | D | R | N | . |
. |
. |
. |
. |
N | Y | Y | A | R | G | F | S |
Template Known Secondary structure |   |
|
| S | S | S | S |
|
| S | S |
|
|
|
|
| T | T | T | S | S |
|
|
| S | T | T |
|
| S |
|
|  |  |  |
|  |  |  |  |  |  | T | T |
|
| B | S |  |  |  |  | T | T | S | T | T |  |  |  |  |  |  |  | T | T |  |  | . | . | . | . | . |  |  |  |  | T | T |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|  |  |
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|
|
| . | . | . | . | . |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
139 | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | |
|
|
|
|
. | . | . | . | 210 | . | . | . |
  |
  |   |
187 | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
P | R | L | A | S | R | S | T | V | L | M | D | G | I | P | V | P | F | A | P | Y | G | Q | P | Q | L | S | L | A | P | V | S | L | G | N | M | D | A | I | D | V | V | R | G | G | G | A | V | R | Y | G | P | Q | S | V | G | G | V | V | N | F | V | T | R | A | I | P | Q | D | F | G | I | E | A | G | V | E | G | Q | L |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|
|   |
|
|
|
|
|
|
|   |
|
|   |
|
|   |   |
|   |
|
|
|
|
|
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
Template Conservation |   |
  |   |   | . | . | . | . | . |
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   | . |   |   |   |   |
|   |   |   |   |
|
|   |
|
|
|
|
|
|   |   |
|
|   |
|
|   |   |
|   |
|
|
|
|
|
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . |
Template Sequence |   |
I | N | N | . |
. |
. |
. |
. |
F | Q | Y | D | G | I | P | S | T | A | R | N | V | G | Y | S | A | . |
G | N | T | L | S | D | X | A | I | Y | D | R | V | E | V | L | K | G | A | T | G | L | L | T | G | A | G | S | L | G | A | T | I | N | L | I | R | K | K | P | T | H | E | F | K | G | H | V | E | L | G | A | . |
. |
Template Known Secondary structure |   |
 |
|
| . | . | . | . | . | B |
| B | T | T | B |
|
|
|
|
|
| S | T | T |
|
| . | S | T | T |
|
| B | S | T | T |  |  |  |  |  |  |  |  |  |
| G | G | G | T | S |
| S |
|
| S |  |  |  | B |
|  |  |  |
|
|
|
| S | S |
|  |  |  |  |  |
|
|  | . | . |
Template Predicted Secondary structure |   |
|
|
| . | . | . | . | . |  |  |  |
|
|  |  |
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
214 | . | . | |
|
|
|
|
. | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | |
. | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | |
|
  |
  |   |
267 | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
S | P | T | S | S | Q | N | N | P | K | E | T | H | N | L | M | V | G | G | T | A | D | N | G | F | G | T | A | L | L | Y | S | G | T | R | G | S | D | W | R | E | H | S | A | T | R | I | D | D | L | M | L | K | S | K | Y | A | P | D | E | V | H | T | F | N | S | L | L | Q | Y | Y | D | G | E | A | D | M | P | G | G |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
. | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. | . | . |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
. |
. |
. |
G | S | W | D | N | Y | R | S | E | L | D | V | S | G | P | L | T | E | S | G | N | V | R | G | R | A | V | A | A | Y | Q | D | K | H | S | F | X | D | H | Y | E | R | K | T | S | V | Y | Y | G | I | L | E | F | D | L | N | P | D | T | X | L | T | V | G | A | D | Y | Q | D | N | D | P | K | G | S | G | W |
Template Known Secondary structure |   |
. | . | . |  | T | T | T |  |  |  |  |  |  |  |  |  |  |  | S | S | T | T |
| S |  |  |  |  |  |  |  |  |  |  |  |
|
|
| S | S | T | T |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
| T | T | S |
|
|  |  |  |  |  |  |  |  |  |  |  |
|
| S |
|
|
|
Template Predicted Secondary structure |   |
. | . | . |  |  |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
286 | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . |
  |
  |   |
347 | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | S | R | A | D | Y | D | A | D | R | W | Q | S | T | R | P | Y | D | R | F | W | G | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
R | R | K | L | A | S | L | G | Y | Q | F | Q | P | D | S | Q | H | K | F | N | I | Q | G | F | Y | T | Q | T | L | R | S | G | Y | L | E | Q | G |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
S | G | S | F | P | L | F | D | S | Q | G | N | R | N | D | V | S | R | S | F | N | N | G | A | K | W | S | S | W | E | Q | Y | T | R | T | V | F | A | N | L | E | H | N | F | A | N | G | W | V | G | K | V | Q | L | D | H | K | I | N | G | Y | H | A | P | L | G | A | I | X | G | D | W | P | A | P | D | N | S | A | K |
Template Known Secondary structure |   |
S | S | S | S |
| S | B |
| S | S | S | S | B |
|
|
|
| T | T |
|
|
| B |
| T | T |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| T | T | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| S | S |
|
|
| T | T | T |
|
|
|
Template Predicted Secondary structure |   |
 |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
363 | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . |
  |
  |   |
406 | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
K | R | I | T | L | S | P | R | N | Y | W | V | R | G | I | E | P | R | Y | S | Q | I | F | M | I | G | P | S | A | H | E | V | G | V | G | Y | R | Y | L | N | E | S | T | H | E | M | R | Y | Y | T | A | T | S | S | G | Q | L | P | S | G | S | S | P | Y | D | R | D | T | R | S | G | T | E | A | H | A | W | Y | L | D |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
I | V | A | Q | K | Y | T | G | E | T | K | S | N | S | L | D | I | Y | L | T | G | P | F | Q | F | L | G | R | E | H | E | L | V | V | G | T | S | A | S | F | S | H | W | E | G | K | S | Y | W | N | L | R | N | Y | D | N | T | T | D | D | F | I | N | W | D | G | D | I | G | K | P | D | W | G | T | P | S | Q | Y | I |
Template Known Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | S | S | S | S |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  | S |
|
|
|
|
| S |
| S | S | S |
|
|
|
|
|
|
|
|  |  |
| S |
| S |  |  |  |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
443 | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . |
  |
  |   |
486 | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | |
|
|
|
|
|
|
|
. | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  | . | . | . | . | . | . | . | . |  |  |
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
D | K | I | D | I | G | N | W | T | I | T | P | G | M | R | F | E | H | . |
. |
. |
. |
. |
. |
. |
. |
I | E | S | Y | Q | N | N | A | I | T | G | T | H | E | E | V | S | Y | N | A | P | L | P | A | L | N | V | L | Y | H | L | T | D | S | W | N | L | Y | A | N | T | E | G | S | F | G | T | V | Q | Y | S | Q | I | G |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
D | D | K | T | R | Q | L | G | S | Y | X | T | A | R | F | N | V | T | D | D | L | N | L | F | L | G | G | R | V | V | D | Y | R | V | T | G | L | N | P | T | I | R | E | S | G | R | F | I | P | Y | V | G | A | V | Y | D | L | N | D | T | Y | S | V | Y | A | S | Y | T | D | I | F | X | P | Q | D | S | W | Y | R | D |
Template Known Secondary structure |   |
 |  |
|
|  |  |
|
|  |  |  |  |  |  |  |  | S | S | S | S |
|  |  |  |  |  |  |  |  |  |  |  |  |
|
| S | S | S | S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| S | S | S |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
| T | T |
|
|
|
Template Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |
|
|
|
|  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
523 | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . |
  |
  |   |
558 | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | |
|
. | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . | . | . | . | . | . | . | 610 | . | |
|
|
. | . | . | . | . | . | . | . | 620 | . | . | . | . | . | . | . | . | . | 630 | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
| . | . | . |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
K | A | V | Q | S | G | N | V | E | P | E | K | A | R | T | W | E | L | G | T | R | Y | D | . |
. |
D | G | A | L | T | A | E | M | G | L | F | L | I | N | F | N | N | Q | Y | D | S | N | Q | T | N | D | T | V | T | A | R | . |
. |
. |
G | K | T | R | H | T | G | L | E | T | Q | A | R | Y | D | L | G | T | L | T | P |
Query Conservation |   |
  |   |   |   |
|   |   |
|   |   |
|   |
|   |   |   |
|   |
|   |   |   |   | . | . |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   | . | . | . |   |   |   |   |   |   |
|   |   |   |   |   |
|   |
|   |   |   |   |   |   |
Alig confidence |   |
. | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. | . |   |   |
|   |   |
|   |
|
|   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |
Template Sequence |   |
. |
. |
S | S | N | K | L | L | E | P | D | E | G | Q | N | Y | E | I | G | I | K | G | E | Y | L | D | G | R | L | N | T | S | L | A | Y | F | E | I | H | E | E | N | R | A | E | E | D | A | L | Y | N | S | K | P | T | N | P | A | I | T | Y | A | Y | K | G | I | K | A | K | T | K | G | Y | E | A | E | I | S | G | E |
Template Known Secondary structure |   |
. | . | S | S | S |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| S | S | T | T | S |
|
|
|
| T | T |
| S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
. | . |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
603 | . | . | . | . | . | . | 610 | . | . | . | . | . | . | . | . | . | 620 | . | . | . | . | . | . | . | . | . | 630 | . | . | . | . | . | . | . | . | . | 640 | . | . | . | . | . | . | . | . | . | 650 | . | . | . | . | . | . | . | . | . | 660 | . | . | . | . | . | . | . | . | . | 670 | . | . | . | . | . | . | . | . | . | 680 |
  |
  |   |
633 | . | . | . | . | . | . | 640 | . | . | . | . | . | . | . | . | . | 650 | . | . | . | . | . | . | . | . | . | 660 | . | . | . | . | . | . | . | . | . | 670 | . | . | . | . | . | . | . | |
|
|
|
. | . | 680 | . | . | . | . | . | . | . | . | . | 690 | . | . | . | . | . | . | . | . | . | 700 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  | . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
T | L | D | N | V | S | I | Y | A | S | Y | A | Y | V | N | A | E | I | R | E | K | G | D | T | Y | G | N | L | V | P | F | S | P | K | H | K | G | T | L | G | V | D | Y | K | P | . |
. |
. |
. |
G | N | W | T | F | N | L | N | S | D | F | Q | S | S | Q | F | A | D | N | A | N | T | V | K | E | S | A | D | G | S | T |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   | . | . | . | . |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   | . | . | . | . |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   | . | . |   |   |   |   |   |   |   |
Template Sequence |   |
L | A | P | G | W | Q | V | Q | A | G | Y | T | H | K | I | I | R | D | D | S | G | . |
. |
. |
. |
K | K | V | S | T | W | E | P | Q | D | Q | L | S | L | Y | T | S | Y | K | F | K | G | A | L | D | K | L | T | V | G | G | G | A | R | W | Q | G | K | S | W | Q | X | V | Y | N | N | . |
. |
P | R | S | R | W | E | K |
Template Known Secondary structure |   |
S | S | S | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
| . | . | . | . |
| B |
|
| T | T | S |
| S |  |  |  |  |  |  |  |  |  |  |
|
| G | G | G | T | T |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |
|
|
| G | . | . | G | G |
|
|
|
|  |
Template Predicted Secondary structure |   |
 |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| . | . |
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
681 | . | . | . | . | . | . | . | . | 690 | . | . | . | . | . | . | . | . | . | 700 | . | |
|
|
|
. | . | . | . | . | . | . | . | 710 | . | . | . | . | . | . | . | . | . | 720 | . | . | . | . | . | . | . | . | . | 730 | . | . | . | . | . | . | . | . | . | 740 | . | . | . | . | . | . | . | |
|
. | . | 750 | . | . | . | . |
  |
  |   |
709 | 710 | . | . | . | . | . | . | . | . | . | 720 | . | . | . | . | . | . | . | . | . | 730 | . | . | . | . | . | . | . | . | . | 740 | . | . | . | . | . | . | . | . | . | 750 | . | . | . | . | . | . | . | . | . | 760 | . | . | . | . | . | . | . | . | . | 770 | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | R | I | P | G | F | M | L | W | G | A | R | V | A | Y | D | F | G | P | Q | M | A | D | L | N | L | A | F | G | V | K | N | I | F | D | Q | D | Y | F | I | R | S | Y | D | D | N | N | K | G | I | Y | A | G | Q | P | R | T | L | Y | M | Q | G | S | L | K | F |
Query Conservation |   |
  |   |   |   |   |
|   |   |   |
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|   |
|
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |   |   |
|   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |
|   |   |   |
|
|   |   |   |
|   |   |   | . | . | . |   |   |   |   |
|   |
|   |
|   |
|
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   | . | . |   |   |   |   |
|
|   |   |   |
|   |   |   |
|   |
|
Template Sequence |   |
F | S | Q | E | D | Y | W | L | V | D | L | X | A | R | Y | Q | I | T | . |
. |
. |
D | K | L | S | A | S | V | N | V | N | N | V | F | D | K | T | Y | Y | T | N | I | G | F | Y | T | S | A | . |
. |
S | Y | G | D | P | R | N | L | X | F | S | T | R | W | D | F |
Template Known Secondary structure |   |
 |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |
| S | . | . | . | S | S |
|  |  |  |  |  |  | T | T | T | T |
|
|
|
|  |  |  | S |
| S | S | S |
|
| . | . |  |  |
|
|
| S |
|
|  |  |  |  |
| S |
|
|
Template Predicted Secondary structure |   |
 |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
| . | . | . |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  | . | . |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
755 | . | . | . | . | 760 | . | . | . | . | . | . | . | . | . | 770 | . | . | |
|
|
. | . | . | . | . | . | . | 780 | . | . | . | . | . | . | . | . | . | 790 | . | . | . | . | . | . | . | . | . | |
|
800 | . | . | . | . | . | . | . | . | . | 810 | . | . | . | . | . |
  |