|   |
163 | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | |
. | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
F | T | M | L | G | L | A | E | S | G | H | W | D | K | V | A | D | M | V | A | N | F | A | H | E | I | D | T | Y | G | H | I | P | N | G | N | R | S | Y | Y | L | S | R | S | Q | P | P | F | F | A | L | M | V | E | L | L | A | Q | H | E | G | D | . |
A | A | L | K | Q | Y | L | P | Q | M | Q | K | E | Y | A | Y | W |
Query Conservation |   |
|
|   |   |
|
|
|   |
|   |   |   |   |   |
|
|   |
|
|   |
|
|   |   |
|
|   |   |   |
|   |
|
|
|
|   |
|   |
|
|
|   |
|
|
|
|
|
|
|
|   |
|
|   |   |   |   |   |   |
|   |
| . |   |   |
|   |   |   |
|
|   |
|
|
|
|
|   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   | . | . | . | . | . | . | . |   |
|   |   |   |
|   |   |   |
|   |   |
|   |   |
|
|
|   |   |   |
|   |   |   |
|   |   |
|   |   |   |
|   |   |   |
Template Sequence |   |
S | Y | L | X | N | Y | Y | L | F | F | D | S | E | S | V | K | R | T | I | W | L | L | R | G | K | D | P | V | T | S | H | S | N | T | I | X | D | . |
. |
. |
. |
. |
. |
. |
Y | T | F | Y | W | F | L | S | V | Y | D | Y | Y | X | Y | S | G | D | R | H | F | V | N | Q | L | Y | P | R | X | Q | T | X | X | D | Y | V |
Template Known Secondary structure |   |
 |  |  |  |  |  | T | T | T |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
| S | S |
|
| S | S | G | G | G | B |  |  | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
348 | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | |
|
|
|
|
|
|
. | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 |
  |
  |   |
242 | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . |
Predicted Secondary structure |   |
 |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
M | D | G | V | E | N | L | Q | A | G | Q | Q | E | K | R | V | V | K | L | Q | D | G | T | L | L | N | R | Y | W | D | D | R | D | T | P | R | P | E | S | W | V | E | D | I | A | T | A | K | S | N | P | N | R | P | A | T | E | I | Y | R | D | L | R | S | A | A | A | S | G | W | D | F | S | S | R | W | M | D | N | P |
Query Conservation |   |
  |   |   |
|
|   |   |   |   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |
|
|   |   |   |   |   |   |
|
|
|
|
|
|
|
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |
|   |   |   |
Template Sequence |   |
L | G | R | T | N | K | N | G | X | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
V | E | G | X | S | G | D | W | V | F | V |
Template Known Secondary structure |   |
 | T | T | B |
| T | T | S |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | B |
|
|
| T | T |
| B |
|
| S |
Template Predicted Secondary structure |   |
 |  |
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
421 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
430 | . | . | . | . | . | . | . | . | . | 440 |
  |
  |   |
322 | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Q | Q | L | N | T | L | R | T | T | S | I | V | P | V | D | L | N | S | L | M | F | K | M | E | K | I | L | A | R | A | S | K | A | A | G | D | N | A | M | A | N | Q | Y | E | T | L | A | N | A | R | Q | K | G | I | E | K | Y | L | W | N | D | Q | Q | G | W | Y | A | D | Y | D | L | K | S | H | K | V | R | N | Q | L |
Query Conservation |   |
  |   |
|   |
|
|   |
|   |   |
|
|
|
|
|
|
|
|   |
|   |   |   |   |   |   |
|
|   |
|
|   |   |
|
|   |   |   |   |
|   |   |
|   |   |   |
|   |   |   |   |   |
|
|   |   |   |
|
|
|
|
|   |
|   |
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |
|   |   |   |
|   |
|
|   |   |
|
|   |   |   |
|
|   |   |
|   |   |   |
|   |   |
|
|   |
|   |   |   |   |
|   |
|   |   |   |
|   |
|   |
|   |   |   |   |
|   |   |   |   |   |   |
|
Template Sequence |   |
D | W | A | D | G | Y | L | D | K | K | G | E | L | S | F | E | Q | V | L | F | C | R | S | L | E | T | X | A | L | C | A | D | L | V | G | D | K | D | G | Q | Q | K | Y | E | K | L | A | S | A | L | K | A | K | L | E | P | T | F | W | N | N | Q | K | Q | A | F | V | H | N | C | V | D | G | R | Q | S | D | A | V | T |
Template Known Secondary structure |   |
|
|
| T | T |
|
|
|
| S | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | T | T |  |  |
| S |  |  |  | T | T |  |  |
| S |
|
|
|
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
441 | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 |
  |
  |   |
402 | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | |
. | . | . | 480 |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  | . |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
Query Sequence |   |
T | A | A | A | L | F | P | L | Y | V | N | A | A | A | K | D | R | A | N | K | M | A | T | A | T | K | T | H | L | L | Q | P | G | G | L | N | T | T | S | V | K | S | G | Q | Q | W | D | A | P | N | G | W | A | P | L | Q | W | V | A | T | E | G | L | Q | N | Y | G | Q | K | E | V | A | M | D | I | . |
S | W | H | F |
Query Conservation |   |
  |   |
|   |   |   |
|
|   |   |
|   |   |   |   |   |   |
|   |   |
|   |   |   |
|   |   |   |
|   |   |   |
|
|
|
|
|
|   |   |   |
|
|   |
|
|
|
|
|
|
|
|   |
|
|
|   |
|
|
|
|
|
|   |   |
|
|   |   |
|
|
|   |   |
| . |
|   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
Template Conservation |   |
|   |
|
|
|
|
|
|   |   |
|
|   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |
|
|   |   |   |   |   |
|
|   |
|
|   |   |   |
|   |   |
|   |
|   |   |   |   |   |   |   |
|
Template Sequence |   |
R | Y | A | N | X | F | S | V | F | F | D | Y | L | N | A | D | K | Q | Q | A | I | K | Q | S | V | L | L | N | D | E | I | L | K | I | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
T | T | P | Y | X | R | F | Y | E | L | E | A | L | C | A | L | G | E | Q | E | T | V | X | K | E | X | K | A | Y | W |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  | T | T |
| S |
|  |  |  |  |  |  |  |  |  |  | T | T | T |
| T | T | S |
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
| S |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
521 | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . |
  |
  |   |
481 | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | |
|
|
. | . | 520 | . | . | . | . | . | . | . | . | . | 530 |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | T | N | V | Q | H | T | Y | D | R | E | K | K | L | V | E | K | Y | D | V | S | T | T | G | T | G | G | G | G | G | E | Y | P | L | Q | D | G | . |
. |
. |
F | G | W | T | N | G | V | T | L | K | M | L | D |
Query Conservation |   |
|   |   |   |   |   |   |   |   |   |
|
|   |
|   |
|
|
|
|
|   |   |   |   |   |   |
|   |
|
|
|
|   |   |
|   |
| . | . | . |
|
|
|
|
|
|
|   |
|   |
|
|   |
Alig confidence |   |
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|
|   |   |
| . | . | . |
|
|
|   |
|
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |
|   |   |   |
|   |   |   |
|   |   |
Template Sequence |   |
G | G | X | L | K | A | G | . |
. |
. |
A | T | S | F | W | E | K | Y | N | P | E | E | S | G | T | Q | H | L | A | X | Y | G | R | P | Y | G | K | S | L | C | H | A | W | G | A | S | P | I | Y | L | L | G | K |
Template Known Secondary structure |   |
 |  |  |  | T | T | T | . | . | . |
| S | S |
|
| S |
|
|
| T | T |
|
| G | G | G | G | G |
| B | T | T | B | T | T |
| S |
| S | S | B | G | G | G |
| T |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |
|
| . | . | . |
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
585 | . | . | . | . | 590 | . | |
|
|
. | . | . | . | . | . | . | . | 600 | . | . | . | . | . | . | . | . | . | 610 | . | . | . | . | . | . | . | . | . | 620 | . | . | . | . | . | . | . | . | . | 630 | . | . | . | . |
  |