|   |
12 | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | |
. | . | . | . | . | 60 | . | . | . | . | . | . | |
. | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  | . |  |  |  |  |  |  |  |  |
|
|
|
| . |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | V | M | V | V | G | D | V | M | L | D | R | Y | W | Y | G | P | T | S | R | I | S | P | E | A | P | V | P | V | V | K | V | N | T | I | E | E | R | P | G | G | A | A | . |
N | V | A | M | N | I | A | S | L | G | A | N | . |
A | R | L | V | G | L | T | G | I | D | D | A | A | R | A | L | S | K | S | L | A | D | V |
Query Conservation |   |
  |
|
|
|
|
|   |   |   |
|
|   |   |   |   |
|   |   |   |
|
|   |
|
|   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |
|
|
|
| . |
|
|
|   |   |
|
|   |
|
|   |   | . |
|   |
|
|
|   |
|
|   |
|   |   |
|   |   |
|   |   |   |
|   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |
|
|
|   |   |   |
|
|   |   |   |   | . | . |   |   |   |   |
| . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |
|   |
|   |   |
|   |   |
|
|   |   |   |
|   |   |
|   |   |   |
|   |
|   |   |
|   |   |
|   |   |   |
|   |   |   |
Template Sequence |   |
V | I | S | V | V | G | S | S | N | I | D | I | V | L | K | . |
. |
V | D | H | F | T | . |
. |
K | P | G | E | T | Q | K | A | I | E | M | N | V | F | P | G | G | K | G | A | N | Q | A | V | T | V | A | K | I | G | E | K | G | C | R | F | V | T | C | I | G | N | D | D | Y | S | D | L | L | I | E | N | Y | E | K | L |
Template Known Secondary structure |   |
|  |  |  |  |
|
|
|  |  |  |  |  |  |  | . | . |
| S | S |
|
| . | . |
| T | T |
|
|
|
|
| S |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  | S | S |
|  |  |  |  |  |  |  |
| S | S |  |  |  |  |  |  |  |  |  |  |  |  | T |
Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|  |  |  |  |  |  | . | . |  |
|
|
|
| . | . |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
4 | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | |
|
. | 20 | . | . | . | |
|
. | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . |
  |
  |   |
90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
N | V | K | C | D | F | V | S | V | P | T | H | P | T | I | T | K | L | R | V | L | S | R | N | Q | Q | L | I | R | L | D | F | E | E | G | F | E | G | V | D | P | Q | P | L | H | E | R | I | N | Q | A | L | S | S | I | G | A | L | V | L | S | D | Y | A | K | G | A | L | A | S | V | Q | Q | M | I | Q | L | A | R | K |
Query Conservation |   |
|
|
|   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
Alig confidence |   |
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
| . | . |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . |   |   |   |
|   |   |   |
|   |
|   |   |   |   |   |   |   | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
G | I | . |
. |
T | G | Y | I | R | V | S | L | P | T | G | R | A | F | I | E | V | D | K | T | G | Q | N | R | I | I | I | F | P | G | A | N | A | E | L | K | K | E | L | I | D | . |
. |
. |
W | N | T | L | S | E | S | D | I | L | L | L | Q | N | E | I | P | . |
. |
. |
. |
. |
F | E | T | T | L | E | C | A | K | R |
Template Known Secondary structure |   |
T |  | . | . |  |  |  |  |  |
| S | S |
|
|
|  |  |  |  |  |  |
| T | T | S |
|  |  |  |  |  |  |
| G | G | G | G | G |
|
| G | G | G |
|
| . | . | . |  |  |  |  | T | T |
| S |  |  |  |  |
| S | S | S |
| . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
| . | . |
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  | . | . | . |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
| . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
80 | . | |
|
. | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | |
|
|
. | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
140 | . | . | . | . | . | . | . | . | . |
  |
  |   |
170 | . | . | . | . | . | . | . | . | . | 180 | |
|
|
. | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|  |  |  |  |
|
|
|
| . | . | . |
|
|  |  |  |  |
|
|
|
|  |  |  |  |
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | G | V | P | V | L | I | D | P | K | G | . |
. |
. |
T | D | F | E | R | Y | R | G | A | T | L | L | T | P | N | L | S | E | F | E | A | V | V | G | K | C | K | T | E | E | E | I | V | E | R | G | M | K | L | I | A | D | Y | E | L | S | A | L | L | V | T | R | S | E | Q | G | M | S | L | L | Q | P | G | K | A | P |
Query Conservation |   |
  |   |   |   |
|   |   |
|   |   |   | . | . | . |   |   |   |   |   |   |   |   |   |
|   |
|   |
|
|   |   |
|   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |   |
|
|
|
|   |
|   |   |
|
|   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|
|   |   |
|   |   |
|   |   |   |   |   |   | . |   |   |   |
Template Sequence |   |
F | N | G | I | V | I | F | D | P | A | P | A | Q | G | I | N | E | E | I | F | Q | Y | L | D | Y | L | T | P | N | E | K | E | I | E | A | L | S | K | D | F | F | G | E | F | L | T | V | E | K | A | A | E | K | F | L | E | L | G | V | K | N | V | I | V | K | L | G | D | K | G | V | L | L | V | N | K | . |
N | E | K |
Template Known Secondary structure |   |
|
| S |  |  |  |  |
|
|
| S |
| T | T |
|
| G | G | G | G | G | G |
| S |  |  |
|
| B |  |  |  |  |  |  |  |  |  |  |  |  | S |
|
|
|
|  |  |  |  |  |  |  |  |  |  | T | T |
| S |  |  |  |  |  |
| G | G | G |
|  |  |  |  |  | T | . | T |  |  |
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
| . |
|  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | |
. | . | . |
  |
  |   |
247 | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | |
|
. | . | . | . | . | . | . | 310 | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
| . | . |
|
|  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | H | M | P | T | Q | A | Q | E | V | Y | D | V | T | G | A | G | D | T | V | I | G | V | L | A | A | T | L | A | A | G | N | S | L | E | E | A | C | F | F | A | N | A | A | A | G | V | V | V | G | K | L | G | T | S | T | . |
. |
V | S | P | I | E | L | E | N | A | V | R | G |
Query Conservation |   |
  |   |   |
|
|   |   |
|   |
|
|
|
|
|
|
|
|
|
|
|   |
|
|
|
|   |   |
|   |   |
|   |   |   |   |
|
|   |   |   |
|   |
|
|
|
|   |   |
|   |   |   |
|
|   |   | . | . |   |   |   |   |
|
|   |   |   |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |
|
|
|
|
|
|
|
|
|   |
|   |
|
|   |   |   |   |
|   |   |
|   |   |   |   |   |
|   |   |   |
|   |   |   |
|
|   |   |   |   |   |   |
|   |   |   |   |   |
|   |   |   |   |
|   |   |   |   |   |   |
Template Sequence |   |
K | H | F | P | T | F | K | V | K | A | V | D | T | T | A | A | G | D | V | F | N | G | A | F | A | V | A | L | S | E | G | K | N | P | E | E | A | V | I | F | G | T | A | A | A | A | I | S | V | T | R | L | G | A | Q | S | S | I | P | A | R | E | E | V | E | A | F | L | K | N |
Template Known Secondary structure |   |
 |  |  |
|
|
|
|
|
|
| S |
|
| T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | S | S | S | S | G | G | G |
|
|
|  |  |  |  |  |  |  |  |  | T |
Template Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
229 | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . |
  |