|   |
12 | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | |
. | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 |
Predicted Secondary structure |   |
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  | . |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | V | M | V | V | G | D | V | M | L | D | R | Y | W | Y | G | P | T | S | R | I | S | P | E | A | P | V | P | V | V | K | V | N | T | I | E | E | R | P | G | G | A | A | . |
N | V | A | M | N | I | A | S | L | G | A | N | A | R | L | V | G | L | T | G | I | D | D | A | A | R | A | L | S | K | S | L | A | D | V | N |
Query Conservation |   |
  |
|
|
|
|
|   |   |   |
|
|   |   |   |   |
|   |   |   |
|
|   |
|
|   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |
|
|
|
| . |
|
|
|   |   |
|
|   |
|
|   |   |
|   |
|
|
|   |
|
|   |
|   |   |
|   |   |
|   |   |   |
|   |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |   |
|
|   |   |   |
|
|   | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |
|   |
|   |   |
|
|   |
|
|   |   |   |   |   |   |   |   |
|
|   |
|   |   |
|   |   |
|   |   |   |
|   |   |   |
|
Template Sequence |   |
D | V | V | S | L | G | E | I | L | V | D | X | . |
. |
. |
. |
. |
. |
. |
. |
I | S | T | E | E | V | N | S | L | S | Q | S | R | E | Y | T | R | H | F | G | G | S | P | A | N | I | A | V | N | L | S | R | L | G | K | K | V | A | L | I | S | R | L | G | A | D | A | F | G | N | Y | L | L | D | V | L | K | G | E | Q |
Template Known Secondary structure |   |
|  |  |  |  | S |
|
|  |  |  |  | . | . | . | . | . | . | . | . |  |
|
|
|
|
| S | S | G | G | G |
|
|
|
|  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|  |  |  |  |
|  |  |  | S | S |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|  |  |  |  | . | . | . | . | . | . | . | . |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
23 | . | . | . | . | . | . | 30 | . | . | . | . | |
|
|
|
|
|
|
|
. | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . |
  |
  |   |
91 | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 |
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | K | C | D | F | V | S | V | P | T | H | P | T | I | T | K | L | R | V | L | S | R | N | Q | Q | L | I | R | L | D | F | E | E | G | F | E | G | V | D | P | Q | P | L | H | E | R | I | N | Q | A | L | S | S | I | G | A | L | V | L | S | D | Y | A | K | G | A | L | A | S | V | Q | Q | M | I | Q | L | A | R | K | A |
Query Conservation |   |
|
|   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
I | I | T | D | G | I | Q | Q | D | K | E | R | R | T | T | I | V | Y | V | S | K | S | T | R | T | P | D | W | L | P | Y | R | E | A | D | X | Y | L | Q | E | D | D | I | I | F | E | L | I | K | K | V | F | H | L | S | T | F | I | L | S | . |
. |
R | K | P | A | R | D | T | A | I | K | A | F | N | Y | A | R | E | Q |
Template Known Secondary structure |   |
| B |
| T | T |
|  |  |  | S | S | S |
|
|
|  |  |  |  |
|
|
| S | S |
|
|
|  |  |  |  |
| S | G | G | G | G |
|
| S |
|
|
|  |  |  |  |  |
|
|  |  |  |  |  | S |  |  |  |  | . | . | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |
| . | . |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
95 | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | |
|
. | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . |
  |
  |   |
171 | . | . | . | . | . | . | . | . | 180 | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|  |  |  |  |
|
|
|
|
|
|  | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |
|
|
|
|  |  |  |  |
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | V | P | V | L | I | D | P | K | G | T | D | F | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
E | R | Y | R | G | A | T | L | L | T | P | N | L | S | E | F | E | A | V | V | G | K | C | K | T | E | E | E | I | V | E | R | G | M | K | L | I | A | D | Y | E | L | S | A | L | L | V | T | R | S | E | Q | G | M |
Query Conservation |   |
  |   |   |
|   |   |
|   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |
|   |
|   |
|
|   |   |
|   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |   |
|
|
|
|   |
|   |   |
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . |   |   |   |   |
|   |   |   |
|   |   |   |
|
|
|
|   |
|   |   |
|   |
Template Sequence |   |
G | K | I | V | C | F | D | P | C | Y | R | K | V | L | W | P | E | G | D | D | G | A | G | V | V | E | E | I | I | S | R | A | D | F | V | K | P | S | L | D | D | A | R | H | L | F | G | P | D | S | P | E | N | . |
. |
. |
. |
. |
Y | V | K | R | Y | L | E | L | G | V | K | A | V | I | L | T | L | G | E | E | G | V |
Template Known Secondary structure |   |
T |
|  |  |  |  |  |
|
|
|
| G | G | G | S |
| S | S | S |
| S |  |  |  |  |  |  |  |  | T | T |
| S |  |  |
|
| B |  |  |  |  |  |  |  |  | T | T | S |
| S | S | G | . | . | . | . | . | G | G | G | G | G | T | T | T | T |
| S |  |  |  |  |  |
| S | T | T |
|  |
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  | . | . | . | . | . |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
175 | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | |
|
|
|
|
. | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . |
  |
  |   |
238 | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
S | L | L | Q | P | G | K | A | P | L | H | M | P | T | Q | A | Q | E | V | Y | D | V | T | G | A | G | D | T | V | I | G | V | L | A | A | T | L | A | A | G | N | S | L | E | E | A | C | F | F | A | N | A | A | A | G | V | V | V |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |
|
|
|
|
|
|
|
|
|
|
|   |
|
|
|
|   |   |
|   |   |
|   |   |   |   |
|
|   |   |   |
|   |
|
|
|
|   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   | . | . | . | . | . | . |   |
|   |
|
|
|
|
|
|
|
|
|   |
|   |
|
|   |   |   |   |
|   |   |
|   |   |   |   |   |
|   |   |   |
|   |   |   |
|
|   |   |
|
Template Sequence |   |
I | A | S | D | G | E | E | I | I | . |
. |
. |
. |
. |
. |
R | I | P | A | F | S | E | D | G | A | G | D | A | F | W | S | G | F | I | C | G | L | L | D | G | Y | T | V | K | R | S | I | K | L | G | N | G | V | A | A | F | K | I |
Template Known Secondary structure |   |
 |  |  |
| S | S |
|  |  | . | . | . | . | . | . |  | S |
| S | S | T | T |
|
|
|  |  |  |  |  |  |  |  |  |  | T | T | S | S |
| S | T | T |  |  |  |  |  |  |  |  |
|
| S | S | S |
|
|
Template Predicted Secondary structure |   |
 |  |  |  |
|
|  |  |  | . | . | . | . | . | . |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
250 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
. | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . |
  |