Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	N	T	L	R	Y	F	D	F	G	A	A	R	P	V	L	L	L	I	A	R	I	A	V	V	L	I	F	I	I	F	G	F	P	K	M	M	G	F	D	G	T	V	Q	Y	M	A	S	L	G	A	P	M	P	M	L	A	A	I	I
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		A	V	V	M	E	V	P	A	A	I	L	I	V	L	G	F	F	T	R	P	L	A	V	L	F	I	F	Y	T	L	G	T	A	V	I	G	H	H	Y	W	D	M	T	G	D	A	V	G	P	N	M	I	N	F	W	K	N	V	S	I
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence		A	G	A	F	L	L	L	A	I	T	G	P	G	A	I	S	L	D	R	R
Secondary structure
SS confidence
Disorder																		?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1adu chain B Region: 9 - 41 Aligned: 33 Modelled: 33 Confidence: 13.3% Identity: 12% PDB header:dna-binding protein Chain: B: PDB Molecule:adenovirus single-stranded dna-binding protein; PDBTitle: early e2a dna-binding protein Phyre2 PDB 1c8m chain 4 Region: 2 - 15 Aligned: 14 Modelled: 14 Confidence: 6.5% Identity: 14% PDB header:virus Chain: 4: PDB Molecule:human rhinovirus 16 coat protein; PDBTitle: refined crystal structure of human rhinovirus 16 complexed2 with vp63843 (pleconaril), an anti-picornaviral drug3 currently in clinical trials Phyre2 1 c1aduB_ 2 c1c8m4_

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c1aduB_ 13.3 12 PDB header:dna-binding protein Chain: B: PDB Molecule:adenovirus single-stranded dna-binding protein; PDBTitle: early e2a dna-binding protein 2 c1c8m4_ 6.5 14 PDB header:virus Chain: 4: PDB Molecule:human rhinovirus 16 coat protein; PDBTitle: refined crystal structure of human rhinovirus 16 complexed2 with vp63843 (pleconaril), an anti-picornaviral drug3 currently in clinical trials

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Transmembrane helix prediction

Transmembrane helices have been predicted in your sequence to adopt the topology shown below

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0