|   |
45 | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | V | D | G | M | S | S | W | W | A | A | I | H | G | Y | N | H | P | Q | L | N | A | A | M | K | S | Q | I | D | A | M | S | H | V | M | F | G | G | I | T | H | A | P | A | I | E | L | C | R | K | L | V | A | M | T | P | Q | P | L | E | C | V | F | L | A | D | S | G | S | V | A | V | E | V | A | M | K | M | A | L |
Query Conservation |   |
  |
|
|   |   |
|
|   |   |   |   |   |
|
|
|   |
|
|   |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |
|
|
|
|
|   |   |   |
|
|
|   |
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
Template Conservation |   |
  |
|
|
|   |   |   |   |   |   |   |
| . | . | . | . |   |
|   |
|   |   |
|   |   |   |
|   |   |   |   |   | . | . | . |   |   |
|   |   |   |   |   |   |   |   |
|   |   |   |
|
|   |   |   |
|   |   | . |   |   |
|   |   |
|   |   |
|
|   |
|   |   |   |
|
| . | . | . | . |
Template Sequence |   |
A | L | G | F | S | S | D | N | I | A | G | A | . |
. |
. |
. |
S | P | E | V | A | Q | A | L | V | K | H | S | S | G | Q | A | . |
. |
. |
G | P | Y | G | T | D | E | L | T | A | Q | V | K | R | K | F | C | E | I | F | E | R | D | . |
V | E | V | F | L | V | P | T | G | T | A | A | N | A | L | C | L | . |
. |
. |
. |
Template Known Secondary structure |   |
|
| B |
| S |
| G | G | G |
|
|
| . | . | . | . |
|  |  |  |  |  |  |  |  |  | T | T | S | S |
|
| . | . | . |
| S | T | T |
| S |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | S |
| . |
|  |  |  |  |  | S |
|  |  |  |  |  |  |  |  |  | . | . | . | . |
Template Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|
|
|
| . | . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
| . | . | . |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
| . |
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
9 | 10 | . | . | . | . | . | . | . | . | . | 20 | |
|
|
|
. | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | |
|
|
. | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | |
60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | |
|
|
|
  |
  |   |
125 | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | |
|
|
. |
Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
| . | . | . |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
Query Sequence |   |
Q | Y | W | Q | A | K | G | E | A | R | Q | R | F | L | T | F | R | N | G | Y | H | G | D | T | F | G | A | M | S | V | C | D | P | D | N | S | M | H | S | L | W | K | G | Y | L | P | E | N | L | F | A | P | A | P | Q | S | R | M | D | G | E | W | D | E | R | D | M | V | G | F | A | R | L | M | A | A | . |
. |
. |
H |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |
|
|   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|   |   |
|   |   | . | . | . |   |
Alig confidence |   |
. | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
Template Conservation |   |
. | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |
Template Sequence |   |
. |
. |
. |
. |
S | A | M | T | P | P | W | G | N | I | Y | C | H | P | A | S | H | I | N | N | D | E | C | G | A | P | E | F | F | S | N | G | A | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
K | L | M | T | V | D | G | P | A | A | K | L | D | I | V | R | L | R | E | R | T | R | E | K | V | G | D |
Template Known Secondary structure |   |
. | . | . | . |  | T | S |
|
| T | T |  |  |  |  |  |
| T | T | S |  |  |  |  | S | S | T | T |  |  |  |  |  | T | T | S |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |
|
|
| G | G | G |
|
|
|  |  |  |  |  |  |  | T | T | S | S | T | T |
|
Template Predicted Secondary structure |   |
. | . | . | . |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
77 | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . |
  |
  |   |
202 | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | |
|
250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
R | H | E | I | A | A | V | I | I | E | P | I | V | Q | G | A | G | G | M | R | M | Y | H | P | E | W | L | K | R | I | R | K | I | C | D | R | E | G | I | L | L | I | A | D | E | I | A | T | . |
. |
G | F | G | R | T | G | K | L | F | A | C | E | H | A | E | I | A | P | D | I | L | C | L | G | K | A | L | T | G | G |
Query Conservation |   |
  |   |   |   |
|
|
|
|   |
|
|   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |
|   |   |
|   |   |
|   |   |   |   |
|   |   |
|
|   |
|
|
|   |
| . | . |
|   |
|
|   |
|   |   |   |   |   |   |   |   |
|   |   |   |
|
|   |   |   |   |
|   |
|   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
Template Sequence |   |
V | H | T | T | Q | P | A | C | V | S | I | T | . |
Q | A | T | E | V | G | S | I | Y | T | L | D | E | I | E | A | I | G | D | V | C | K | S | S | S | L | G | L | H | M | D | G | S | R | F | A | N | A | L | V | S | L | G | C | S | P | A | E | M | T | W | K | A | G | V | D | A | L | S | F | G | A | T | K | N | G | V |
Template Known Secondary structure |   |
T | T | S |
|  |  |  |  |  |  |  |  | . | S | S |
| T | T | S |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |  | T |
|
| T | T | T | T | T | G | G | G | T |
|
|  |  |  |  |
|
| G | G | G | T |
|
Template Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |  | . |
|
|
|
|
|
|  |  |
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |
|
|  |  |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
137 | . | . | 140 | . | . | . | . | . | . | . | . | |
. | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . |
  |
  |   |
280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
T | M | T | L | S | A | T | L | T | T | R | E | V | A | E | T | I | S | N | G | E | A | G | C | F | M | H | G | P | T | F | M | G | N | P | L | A | C | A | A | A | N | A | S | L | A | I | L | E | S | G | D | W | Q | Q | Q | V | A | D | I | E | V | Q | L | R | E | Q | L | A | P | A | R | D | A | E | M | V | A | D | V |
Query Conservation |   |
  |   |   |   |
|   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|
|   |
|
|
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |   |   |   |
|   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |
Template Sequence |   |
L | A | A | E | A | I | V | L | F | N | T | S | L | A | T | E | M | S | Y | R | R | K | R | . |
. |
. |
A | G | H | L | S | S | K | M | R | F | L | S | A | Q | I | D | A | Y | L | T | D | D | L | W | L | R | N | A | R | K | A | N | A | A | A | Q | R | L | A | Q | G | L | E | G | L | G | G | V | E | V | L | G | G | T |
Template Known Secondary structure |   |
S | S |
|  |  |  |  |  | S | S | G | G | G |  |  |  |  |  |  |  |  |  |  | . | . | . | T | T |
|
|
| S | S | T |  |  |  |  |  |  |  |  |  |  | T | S | T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
| T | T |  |  |  |  | S |
|
|
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
| . | . | . |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
216 | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | |
|
|
. | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . |
  |
  |   |
360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | |
|
|
. | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 |
Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |
|
| . | . | . |
|  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
R | V | L | G | A | I | G | V | V | E | T | T | H | P | V | N | M | A | A | L | Q | K | F | F | V | E | Q | G | V | W | I | R | P | F | G | . |
. |
. |
K | L | I | Y | L | M | P | P | Y | I | I | L | P | Q | Q | L | Q | R | L | T | A | A | V | N | R | A |
Query Conservation |   |
|
|   |
|   |
|   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |
|
|   |   |   |   |   |
| . | . | . |   |   |
|
|   |   |
|   |   |   |   |
|   |
|
|
|
|   |   |   |   |   |
|   |   |   |
Alig confidence |   |
|
| . | . |
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   | . | . |   |   |
|   |   |   |   |   |   | . | . | . | . | . |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|
|
|   |   |   |   |   |   |
|   |
|
|
|
|   |   |
|   |   |
|   |   |
|
Template Sequence |   |
E | A | . |
. |
N | I | L | F | C | R | L | D | S | . |
. |
. |
. |
. |
A | M | I | D | A | L | L | K | A | G | F | G | F | Y | H | D | R | W | G | P | N | V | V | R | F | V | T | S | F | A | T | T | A | E | D | V | D | H | L | L | N | Q | V | R | L | A |
Template Known Secondary structure |   |
| S | . | . | S |  |  |  |  |  |  |
|  | . | . | . | . | . |  |  |  |  |  |  |  |  | T | T |
| B |
| B |
| S | S | S | S | T | T |  |  |  |  |  |
|
| T | T |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | T |
Template Predicted Secondary structure |   |
|
| . | . |
|  |  |  |  |  |
|
|  | . | . | . | . | . |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
293 | . | |
|
. | . | . | . | . | 300 | . | . | . | |
|
|
|
|
. | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . |
  |