Job Description P12995 Confidence 99.95% Date Thu Jan 5 11:33:14 GMT 2012 Rank 60 Aligned Residues 352 % Identity 12% Template c3e9kA_ PDB info PDB header:hydrolase Chain: A: PDB Molecule:kynureninase; PDBTitle: crystal structure of homo sapiens kynureninase-3-hydroxyhippuric acid2 inhibitor complex Resolution 1.70 Å

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		40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.							.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.
Predicted Secondary structure																																															.	.	.	.	.	.
Query SS confidence																																															.	.	.	.	.	.
Query Sequence		S	D	G	R	R	L	V	D	G	M	S	S	W	W	A	A	I	H	G	Y	N	H	P	Q	L	N	A	A	M	K	S	Q	I	D	A	M	S	H	V	M	F	G	G	I	T	.	.	.	.	.	.	H	A	P	A	I	E	L	C	R	K	L	V	A	M	T	P	Q	P	L	E	C	V	F	L	A	D	S	G	S
Query Conservation																																															.	.	.	.	.	.
Alig confidence													.	.	.	.	.	.																													.	.	.	.	.	.
Template Conservation													.	.	.	.	.	.
Template Sequence		D	E	N	A	I	Y	F	L	G	N	S	.	.	.	.	.	.	L	G	L	Q	P	K	M	V	K	T	Y	L	E	E	E	L	D	K	W	A	K	I	A	A	Y	G	H	E	V	G	K	R	P	W	I	T	G	D	E	S	I	V	G	L	M	K	D	I	V	G	A	N	E	K	E	I	A	L	M	N	A	L	T
Template Known Secondary structure		T		B					B	T	T	T	.	.	.	.	.	.	S			B		T	T																G	G	G	G	G	T	S	S	S	S		G	G	G	T	T					G	G	G					T			G	G	G					S
Template Predicted Secondary structure													.	.	.	.	.	.
Template SS confidence
		65	.	.	.	.	70	.	.	.	.	.							.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.
		114	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		V	A	V	E	V	A	M	K	M	A	L	Q	Y	W	Q	A	K	G	E	A	R	Q	R	F	L	T	F	R	N	G	Y	H	G	D	T	F	G	A	M	S	V	C	D	P	D	N	S	M	H	S	L	W	K	G	Y	L	P	E	N	L	F	A	P	A	P	Q	S	R	M	D	G	E	W	D	E	R	D	M	V	G
Query Conservation
Alig confidence									.	.	.	.																																															.	.	.	.	.	.	.	.	.	.	.
Template Conservation									.	.	.	.																																															.	.	.	.	.	.	.	.	.	.	.
Template Sequence		V	N	L	H	L	L	M	.	.	.	.	L	S	F	F	K	P	T	P	K	R	Y	K	I	L	L	E	A	K	A	F	P	S	D	H	Y	A	I	E	S	Q	L	Q	L	H	G	L	N	I	E	E	S	M	R	M	I	K	.	.	.	.	.	.	.	.	.	.	.	P	R	E	G	E	E	T	L	R	I	E	D
Template Known Secondary structure									.	.	.	.								S	S	S							T	T																T	T												.	.	.	.	.	.	.	.	.	.	.			T	T		S	S
Template Predicted Secondary structure									.	.	.	.																																															.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		139	140	.	.	.	.	.					.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.												.	.	.	.	.	.	.	.	200	.	.	.
		194	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		F	A	R	L	M	A	A	H	R	H	E	I	A	A	V	I	I	E	P	I	V	Q	G	A	G	G	M	R	M	Y	H	P	E	W	L	K	R	I	R	K	I	C	D	R	E	G	I	L	L	I	A	D	E	I	A	T	G	F	G	R	T	G	K	L	F	A	C	E	H	A	E	I	A	P	D	I	L	C	L	G
Query Conservation
Alig confidence																						.										.	.	.	.																							.	.	.
Template Conservation																						.										.	.	.	.																							.	.	.
Template Sequence		I	L	E	V	I	E	K	E	G	D	S	I	A	V	I	L	F	S	G	V	.	H	F	Y	T	G	Q	H	F	N	.	.	.	.	I	P	A	I	T	K	A	G	Q	A	K	G	C	Y	V	G	F	D	L	A	H	A	.	.	.	V	G	N	V	E	L	Y	L	H	D	W	G	V	D	F	A	C	W	C	S	Y
Template Known Secondary structure										G	G	G								S	B	.		T	T	T		B	B			.	.	.	.											T	T								T	T	T	.	.	.	T	T	T	S								T								S	S
Template Predicted Secondary structure																						.										.	.	.	.																							.	.	.
Template SS confidence
		204	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.		.	.	.	.	.	.	230	.	.					.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.				.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.
		274	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.																								.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330
Predicted Secondary structure																																		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence																																		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		K	A	L	T	G	G	T	M	T	L	S	A	T	L	T	T	R	E	V	A	E	T	I	S	N	G	E	A	G	C	F	M	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	H	G	P	T	F	M	G	N	P	L	A	C	A	A	A	N	A	S	L	A	I	L	E	S	G
Query Conservation																																		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence																																		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		K	Y	L	N	A	G	A	G	G	I	A	G	A	F	I	H	E	K	H	A	H	T	I	K	P	A	L	V	G	W	F	G	H	E	L	S	T	R	F	K	M	D	N	K	L	Q	L	I	P	G	V	C	G	F	R	I	S	N	P	P	I	L	L	V	C	S	L	H	A	S	L	E	I	F	K	Q	A	T	M	K
Template Known Secondary structure		S	T	T				T	T									G	G	G	T	T	T	S			S	S			G	G	G	B						T	T			S				B		S	S	G	G	G	G			S
Template Predicted Secondary structure
Template SS confidence
		276	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.
		331	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.				.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.		.	.	.	.	.	400	.		.	.	.	.
Predicted Secondary structure																							.	.	.																																												.								.
Query SS confidence																							.	.	.																																												.								.
Query Sequence		D	W	Q	Q	Q	V	A	D	I	E	V	Q	L	R	E	Q	L	A	P	A	R	.	.	.	D	A	E	M	V	A	D	V	R	V	L	G	A	I	G	V	V	E	T	T	H	P	V	N	M	A	A	L	Q	K	F	F	V	E	Q	G	V	W	I	R	P	F	G	.	K	L	I	Y	L	M	P	.	P	Y	I	I
Query Conservation																							.	.	.																																												.								.
Alig confidence																							.	.	.																							.	.																				.								.
Template Conservation																																																.	.
Template Sequence		A	L	R	K	K	S	V	L	L	T	G	Y	L	E	Y	L	I	K	H	N	Y	G	V	V	N	I	I	T	P	S	H	V	E	E	R	G	C	Q	L	T	I	T	F	S	V	P	.	.	N	K	D	V	F	Q	E	L	E	K	R	G	V	V	C	D	K	R	N	P	N	G	I	R	V	A	P	V	P	L	Y	N
Template Known Secondary structure																													S		S	S	G	G	G	B		S									T	.	.	T									T	T	T							T	T	T					B			T	T	T
Template Predicted Secondary structure																																																.	.
Template SS confidence
		356	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.			.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.
		406	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		L	P	Q	Q	L	Q	R	L	T	A	A	V	N	R	A	V	Q
Query Conservation
Alig confidence
Template Conservation
Template Sequence		S	F	H	D	V	Y	K	F	T	N	L	L	T	S	I	L	D
Template Known Secondary structure																		T
Template Predicted Secondary structure
Template SS confidence
		443	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.

No model constructed - rank, confidence too low

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Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions