|   |
5 | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | |
. | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|  |  |  |
|
|  |  |  |
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
| . |
|
|
|  |  |  |  |
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
K | L | Y | S | P | L | K | V | G | A | I | T | A | A | N | R | I | F | M | A | P | L | T | R | L | R | S | I | E | P | G | D | I | P | T | P | L | M | A | E | Y | Y | R | Q | R | A | . |
S | A | G | L | I | I | S | E | A | T | Q | I | S | A | Q | A | K | G | Y | A | G | A | P | G | I | H | S | P | E | Q | I | A | A |
Query Conservation |   |
  |
|
|   |
|   |   |
|
|   |   |   |
|
|
|
|
|
|   |   |
|
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |
|
| . |   |   |
|
|
|
|   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|
|   |
|
|
|
|
|   |   |   |
|
|
|
|
|
|   |
|
|
|   |   |   |   |   |   | . | . |   |
|   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |
|
|
|
|
|
|   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |
|   |   |
Template Sequence |   |
P | L | L | T | P | Y | K | M | G | R | F | N | L | S | H | R | V | V | L | A | P | L | T | R | Q | R | S | Y | . |
. |
G | N | V | P | Q | P | H | A | A | I | Y | Y | S | Q | R | T | T | P | G | G | F | L | I | T | E | A | T | G | V | S | D | T | A | Q | G | Y | Q | D | T | P | G | I | W | T | K | E | H | V | E | A |
Template Known Secondary structure |   |
G | G | G | S |
|  |  |  | T | T |  |  |  | S |
| S |  |  |  |
|
|
|
|
|
|
| S | G | . | . | G | G |
|
|
|  |  |  |  |  |  |  |  |  | T |
|
| T | T |
|  |  |  |
| S |
|  |  | S | S | T | T |
|
|
| S | T | T |
|
| B |
| S | S |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|  |  |  |
|
|  |  |  |
|
|
|  |  |  |
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
11 | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | |
|
. | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . |
  |
  |   |
84 | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
W | K | K | I | T | A | G | V | H | A | E | N | G | H | M | A | V | Q | L | W | H | T | G | R | I | S | H | A | S | L | Q | P | G | G | Q | A | P | V | A | P | S | A | L | S | A | G | T | R | T | S | L | R | D | E | N | G | Q | A | I | R | V | E | T | S | M | P | R | A | L | E | L | E | E | I | P | G | I | V | N | D |
Query Conservation |   |
  |   |   |
|   |   |   |
|
|   |   |
|   |   |   |   |   |
|
|   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |
|
|   |   |
|
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |
|
|   |   |
|
|   |   |
|   |   |   |   |   |
|
|   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . |
|   |   |
|
|   |   |
|
|   |   |
|
|   |   |
Template Sequence |   |
W | K | P | I | V | D | A | V | H | A | K | G | G | I | F | F | C | Q | I | W | H | V | G | R | V | S | N | S | G | F | Q | P | N | G | K | A | P | I | S | C | S | D | K | P | L | M | P | Q | I | R | S | N | G | I | D | E | A | L | F | T | P | . |
. |
. |
. |
P | R | R | L | G | I | E | E | I | P | G | I | V | N | D |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |  |  |
|
| T | T | S | S |
| G | G | G | S | G | G | G |
|
|
|  |  | S | S |
|
|
| S |
| T | T |
| B |
| S | S | S | S | S | B | S | S |
|
| . | . | . | . |
|  |  |
|
| G | G | G | S |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
89 | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | |
|
|
|
150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . |
  |
  |   |
164 | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
F | R | Q | A | I | A | N | A | R | E | A | G | F | D | L | V | E | L | H | S | A | H | G | Y | L | L | H | Q | F | L | S | P | S | S | N | H | R | T | D | Q | Y | G | G | S | V | E | N | R | A | R | L | V | L | E | V | V | D | A | G | I | E | E | W | G | A | D | R | I | G | I | R | V | S | P | I | G | T | F | Q | N |
Query Conservation |   |
|   |   |
|
|   |
|
|   |   |
|
|
|
|
|
|
|
|
|   |
|
|
|
|
|
|   |
|
|
|
|
|   |   |
|   |
|
|
|
|
|
|
|
|   |
|
|
|   |
|   |   |   |
|
|
|   |
|
|
|   |   |
|
|   |   |   |
|   |
|
|
|
|   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |
|
|   |
|
|   |   |
|
|
|
|
|
|
|
|
|   |
|
|
|
|
|
|   |
|
|
|
|
|   |   |
|   |
|
|
|   |
|
|
|
|   |
|
|
|   |
|
|   |   |
|
|
|   |
|
|
|   |   |   |
|   |
|   |
|   |
|
|   |
|   |   |   |   |   |   |   |
Template Sequence |   |
F | R | L | A | A | R | N | A | M | E | A | G | F | D | G | V | E | I | H | G | A | N | G | Y | L | I | D | Q | F | M | K | D | T | V | N | D | R | T | D | E | Y | G | G | S | L | Q | N | R | C | K | F | P | L | E | I | V | D | A | V | A | K | E | I | G | P | D | R | V | G | I | R | L | S | P | F | A | D | Y | M | E |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  | T |
| S |  |  |  |  |  |  |
| T | T | S |  |  |  |  |  |  |
| T | T | T |
|
|
|
| S | T | T | S | S | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| G | G | G |  |  |  |  |  |
| T | T |
|
| T | T | T |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
165 | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . |
  |
  |   |
244 | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
T | D | N | G | P | N | E | E | A | D | A | L | Y | L | I | E | Q | L | G | K | R | G | I | A | Y | L | H | M | S | E | P | D | W | A | G | G | E | P | Y | T | D | A | F | R | E | K | V | R | A | R | F | H | G | P | I | I | G | A | G | A | Y | T | V | E | K | A | E | T | L | I | G | K | G | L | I | D | A | V | A | F |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |   |
|
|
|   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |
|
|
|
|   |   |
|   |
|
|   |
|   |
|
|   |   |
|   |   |
|   |
|
|   |
|   |
|
Alig confidence |   |
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  | . |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|
|
|   |
|   |
|
|   |   |   |   |   | . | . | . | . | . | . | . | . |   |   |   |   |
|
|   |   |   |   |   |
|
|
|   |   |
|   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |
|   |
|   |   |
Template Sequence |   |
S | . |
G | D | T | N | P | G | A | L | G | L | Y | M | A | E | S | L | N | K | Y | G | I | L | Y | C | H | V | I | E | A | R | M | H | . |
. |
. |
. |
. |
. |
. |
. |
T | L | M | P | M | R | K | A | F | K | G | T | F | I | S | A | G | G | F | T | R | E | D | G | N | E | A | V | S | K | G | R | T | D | L | V | A | Y |
Template Known Secondary structure |   |
| . |
|
| S | S |  |  |  |  |  |  |  |  |  |  |  | T | T | T | T | T |
| S |  |  |  |  |  |
|
|
|
|
| . | . | . | . | . | . | . | . |
|  |  |  |  |  |  |  |
|
| S |  |  |  |  |  | S | S |
|
|  |  |  |  |  |  |  |  |  | T | T | S |
| S |  |  |  |  |
Template Predicted Secondary structure |   |
| . |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|  |  | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
245 | |
. | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
. | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . |
  |
  |   |
324 | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | |
. | . | . | . | . | 360 | . | . | . | . | . |
Predicted Secondary structure |   |
|
|  |  |  |  |
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | R | D | W | I | A | N | P | D | L | V | A | R | L | Q | R | K | A | E | L | N | P | Q | R | A | E | S | F | Y | G | G | . |
G | A | E | G | Y | T | D | Y | P | T | L |
Query Conservation |   |
|
|   |   |
|
|
|
|   |
|   |   |
|   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   | . |   |   |   |   |
|   |
|
|
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|   |   |
|
|
|
|
|   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |
Template Sequence |   |
G | R | W | F | L | A | N | P | D | L | P | K | R | F | Q | V | D | A | P | L | N | K | Y | D | R | P | T | F | Y | T | S | D | P | V | V | G | Y | T | D | Y | P | F | L |
Template Known Secondary structure |   |
S |  |  |  |  |  |
| T | T |  |  |  |  |  |  |  | T |
|
|
|
|
|
|
| G | G | G | S | S |
|
|
| S | S | T | T | T | T |
| S |
|
|
|
Template Predicted Secondary structure |   |
|
|  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|  |  |  |
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
326 | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . |
  |