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Job DescriptionP77258
Confidence99.59%DateThu Jan 5 12:26:56 GMT 2012
Rank30Aligned Residues251
% Identity16%Templatec2fptA_
PDB info PDB header:oxidoreductaseChain: A: PDB Molecule:dihydroorotate dehydrogenase, mitochondrial; PDBTitle: dual binding mode of a novel series of dhodh inhibitors
Resolution2.40 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   910.........20.........30.........40.........50.........60... ......70........
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Query Sequence  PLKVGAITAANRIFMAPLTRLRSIEPGDIPTPLMAEYYRQRASAGLIISEATQIS. AQAKGYAGAPGIHSP. . . . . . . . .
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Template Sequence  EVRVLGHKFRNPVGIAA. . . . . . . . . . GFDKHGEAVDGLYKMGFGFVEIGSVTPKPQEGNPRPRVFRLPEDQAVINRYGF
Template Known Secondary structure 
TTSSS
T..........TTTTTSS
TT
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B

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GGGT



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   80.........90...... ...100.........110.........120.........130.........140.........
 
   7980.........90.........100.........110.........120.........130.........140.........
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Query Sequence  . . . . . . . . . EQIAAWKKITAGVHAENGHMAVQLWHTGRISHASLQPGGQAPVAPSALSAGTRTSLRDENGQAIRVETSMP
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Template Sequence  NSHGLSVVEHRLRARQQKQAKLTEDGLPLGVNL. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . GK
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B

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   150.........160.........170.........180.. ..
 
   150.........160.........170.........180.........190..... ....200.........210.........220........
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Query Sequence  RALELEEIPGIVNDFRQAIANAREAGFDLVELHSAHGYLLHQFLSP. SSNHRTDQYGGSVENRARLVLEVVDAGIEEWGA
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Template Sequence  NKTSVDAAEDYAEGVRVL. . . . . GPLADYLVVNVS. . . . . . . . . SPNTAGLRSLQGKAELRRLLTKVLQERDGLRRVH. R
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TT
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TTSTTSGGGGSTS
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   185....190.........200.. .......210.... .....220.........230.........240........ .
 
   229230.........240.........250.........260.........270.........280.. .......
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Query Sequence  DRIGIRVSPIGTFQNTDNGPNEEADALYLIEQLGKRGIAYLHMSEPDWAGGEPY. . . . . . . . . . . . . . . . . . . TDAFREK
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Template Sequence  PAVLVKIAP. . . . . . . . . . DLTSQDKEDIASVVKELGIDGLIVTNTTVSRPAGLQGALRSETGGLSGKPLRDLSTQTIRE
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   250........ .260.........270.........280.........290.........300.........310.........
 
   290.... .....300.... .....310.........320........ .330.........340
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Query Sequence  VRARF. . HGPIIGAGAY. TVEKAETLIGKGLIDAVAFGRDWI. ANPDLVARLQRK
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Template Sequence  MYALTQGRVPIIGVGGVSSGQDALEKIRAG. ASLVQLYTALTFWGPPVVGKVKRE
Template Known Secondary structure  TTT
S
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ST.
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   320.........330.........340......... 350.........360.........370...
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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