|   |
4 | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | |
. | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . |
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
I | N | T | K | V | K | K | A | V | I | P | V | A | G | L | G | T | R | M | L | P | A | T | K | A | I | P | K | E | M | L | P | L | V | D | K | P | L | I | Q | Y | V | V | N | E | C | I | A | A | G | . |
I | T | E | I | V | L | V | T | H | S | S | K | N | S | I | E | N | H | F | D | T | S | F | E | L | E | A | M | L |
Query Conservation |   |
  |   |   |   |
|   |
|
|
|
|
|
|
|
|   |
|
|
|
|   |
|   |
|   |   |   |
|
|   |
|
|
|
|   |
|
|
|
|
|
|   |   |
|   |   |
|   |   |
|
| . |
|   |   |
|   |
|
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
| . |
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
Template Conservation |   |
|   |   |   |
|
| . |   |
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |   |   |
|
|   |
|   |   |
|   |
|
|
|
|
|   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . |
Template Sequence |   |
M | E | K | S | V | S | . |
V | I | L | L | A | G | G | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
S | M | P | K | Q | Y | I | P | L | L | G | Q | P | I | A | L | Y | S | F | F | T | F | S | R | M | P | E | V | K | E | I | V | V | V | C | D | P | F | F | R | D | I | F | E | E | Y | E | E | S | I | D | V | . |
. |
. |
. |
Template Known Secondary structure |   |
| T | T |
|  |  | . |  |  |  |  |
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
| T | T | T | S |  |  | T | T |  |  |  |  |  |  |  |  |  |  |  |  | T |
| T | T |  |  |  |  |  |  |  |
|
| G | G | G | T |  |  |  |  | T | T | T | T | S |
| S | S | . | . | . | . |
Template Predicted Secondary structure |   |
|
|
|
|  |  | . |  |  |  |  |
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
| . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
75 | . | . | . | . | 80 | |
. | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
. | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | |
|
|
|
  |
  |   |
83 | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | |
|
. | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 |
Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
| . | . |
|
|
|  |  |  |  |  |
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | K | R | V | K | R | Q | L | L | D | E | V | Q | S | I | C | P | P | H | V | T | I | M | Q | V | R | Q | G | L | A | K | G | L | G | H | A | V | L | C | A | H | P | V | V | G | . |
. |
D | E | P | V | A | V | I | L | P | D | V | I | L | D | E | Y | E | S | D | L | S | Q | D | N | L | A | E | M | I | R | R | F | D |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |
|   |   |   |   |
|
|
|   |
|
|   |   |
|   |   |   |   |   | . | . |   |
|   |   |
|
|   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   | . | . | . | . | . | . |
|
|
|   |   |   |   |
|   |   |   |   |   |   |   |   |
Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
D | L | R | F | A | I | P | G | K | E | R | Q | D | S | V | Y | S | G | L | Q | E | I | D | V | N | S | E | L | V | C | I | H | D | S | A | R | . |
. |
. |
. |
. |
. |
P | L | V | N | T | E | D | V | E | K | V | L | K | D | G | S |
Template Known Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |
|
|
| S | S |  |  |  |  |  |  |  |  |  |  | T | S |
| T | T |
| S |  |  |  |  |  |  | T | T |
| . | . | . | . | . | . | T | T |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
| . | . | . | . | . | . |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
147 | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | |
|
|
|
|
|
. | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . |
  |
  |   |
161 | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 |
Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | T | G | H | S | Q | I | M | V | E | P | V | A | D | V | T | A | Y | G | V | V | D | C | K | G | V | E | L | A | P | G | E | S | V | P | M | V | G | V | V | E | K | P | K | A | D | V | A | P | S | N | L | A | I | V | G | R | Y | V | L | S | A | D | I | W | P | L | L | A | K | T | P | P | G | A | G | D | E | I | Q |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|
|
|   |   |   |   |   |   |   |   |
|   |   |   |
|
|
|
|   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . |   |   |   |
Template Sequence |   |
A | V | G | A | A | V | L | G | V | P | A | K | A | T | I | K | E | . |
. |
. |
. |
. |
V | N | S | D | S | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
L | V | V | T | L | W | E | M | Q | T | P | Q | V | I | K | P | E | L | L | K | K | G | F | E | L | V | K | S | E | . |
. |
G | L | E |
Template Known Secondary structure |   |
 |  | S |  |  |  |  |  |  |  |
|
| S |
|
|
|
| . | . | . | . | . | B |
| T | T | S | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
| B |
|
|
|  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  | S | . | . |
|
|
|
Template Predicted Secondary structure |   |
 |
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  | . | . | . | . | . |  |
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
| . | . |
|  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
199 | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | |
|
|
|
|
. | . | . | . | 220 | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | |
|
250 | . | . |
  |
  |   |
241 | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | T | D | A | I | D | M | L | I | E | K | E | T | V | E | A | Y | H | M | K | G | K | S | H | D | C | G | N | K | L | G | Y | M | Q | A | F | V | E | Y | G |
Query Conservation |   |
|   |
|   |
|   |   |
|   |   |   |   |   |
|   |   |   |   |   |   |
|   |
|   |
|
|
|   |
|   |   |
|   |   |
|   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |
|   |   |   |   |   |   |   |
|
|
|
|
|
|
|
|   |   |
|
|   |
|
|   |
Template Sequence |   |
V | T | D | V | S | I | V | E | Y | L | K | H | P | V | Y | V | S | Q | G | S | Y | T | N | I | K | V | T | T | P | D | D | L | L | L | A | E | R | I | L | S |
Template Known Secondary structure |   |
|
|
|
|
| T | T | G | G | G | S | S |
|
|  |  |  |  |
|
| T | T |
|
|
|
|
| S |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
259 | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . |
  |