Job Description P76403 Confidence 97.07% Date Thu Jan 5 12:22:42 GMT 2012 Rank 31 Aligned Residues 138 % Identity 20% Template c2cw6B_ PDB info PDB header:lyase Chain: B: PDB Molecule:hydroxymethylglutaryl-coa lyase, mitochondrial; PDBTitle: crystal structure of human hmg-coa lyase: insights into2 catalysis and the molecular basis for3 hydroxymethylglutaric aciduria Resolution 2.10 Å

Show / Hide SS confidence

Show / Hide Conservation and Alignment quality

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.						.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Predicted Secondary structure																																						.	.	.	.	.																																			.	.	.	.	.
Query SS confidence																																						.	.	.	.	.																																			.	.	.	.	.
Query Sequence		M	F	K	P	E	L	L	S	P	A	G	T	L	K	N	M	R	Y	A	F	A	Y	G	A	D	A	V	Y	A	G	Q	P	R	Y	S	L	.	.	.	.	.	R	V	R	N	N	E	F	N	H	E	N	L	Q	L	G	I	N	E	A	H	A	L	G	K	K	F	Y	V	V	V	N	I	A	P	.	.	.	.	.
Query Conservation																																						.	.	.	.	.																																			.	.	.	.	.
Alig confidence																																						.	.	.	.	.																																			.	.	.	.	.
Template Conservation
Template Sequence		F	P	G	I	N	Y	P	V	L	T	P	N	L	K	G	F	E	A	A	V	A	A	G	A	K	E	V	V	I	F	G	A	A	S	E	L	F	T	K	K	N	I	N	C	S	I	E	E	S	F	Q	R	F	D	A	I	L	K	A	A	Q	S	A	N	I	S	V	R	G	Y	V	S	C	A	L	G	C	P	Y	E
Template Known Secondary structure			T	T		B							S										T	T		S								S									T	S	S		T	T	T															T	T									S	T	T		B	T	T	T
Template Predicted Secondary structure
Template SS confidence
		98	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.
		71	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.											.	100	.	.	.	.	.	.	.	.	.	110	.	.	.					.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.
Predicted Secondary structure																														.	.	.	.	.	.	.	.	.	.																.	.	.	.
Query SS confidence																														.	.	.	.	.	.	.	.	.	.																.	.	.	.
Query Sequence		H	N	A	K	L	K	T	F	I	R	D	L	K	P	V	V	E	M	G	P	D	A	L	I	M	S	D	P	.	.	.	.	.	.	.	.	.	.	G	L	I	M	L	V	R	E	H	F	P	E	M	P	I	.	.	.	.	H	L	S	V	Q	A	N	A	V	N	W	A	T	V	K	F	W	Q	Q	M	G	L	T
Query Conservation																														.	.	.	.	.	.	.	.	.	.																.	.	.	.
Alig confidence																														.	.	.	.	.	.	.	.	.	.																.	.	.	.																.	.	.
Template Conservation																																																																										.	.	.
Template Sequence		G	K	I	S	P	A	K	V	A	E	V	T	K	K	F	Y	S	M	G	C	Y	E	I	S	L	G	D	T	I	G	V	G	T	P	G	I	M	K	D	M	L	S	A	V	M	Q	E	V	P	L	A	A	L	A	V	H	C	H	D	T	Y	G	Q	A	L	A	N	T	L	M	A	L	.	.	.	Q	M	G	V	S
Template Known Secondary structure		B	S																T	T		S							T	T																			S		G	G	G						B		T	T	S											.	.	.		T	T
Template Predicted Secondary structure																																																																										.	.	.
Template SS confidence
		178	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.				250	.	.	.	.
		137	.	.	140	.
Predicted Secondary structure
Query SS confidence
Query Sequence		R	V	I	L	S
Query Conservation
Alig confidence
Template Conservation
Template Sequence		V	V	D	S	S
Template Known Secondary structure						B
Template Predicted Secondary structure
Template SS confidence
		255	.	.	.	.

No model constructed - rank, confidence too low

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions