|   |
56 | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | |
|
|
|
|
. | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 |
Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  | . | . | . | . | . |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Y | G | R | R | G | T | L | T | H | F | S | L | Q | Q | A | M | C | E | L | E | G | G | A | G | C | . |
. |
. |
. |
. |
V | L | F | P | C | G | A | A | A | V | A | N | S | I | L | A | F | I | E | Q | G | D | H | V | L | M | T | N | T | A | Y | E | P | S | Q | D | F | C | S | K | I | L | S | K | L | G | V | T | T | S |
Query Conservation |   |
|   |
|   |   |   |
|
|   |   |   |
|
|   |   |
|
|   |
|   |
|   |   |   |   | . | . | . | . | . |
|   |   |   |
|
|   |   |
|   |   |   |
|
|   |
|
|
|   |   |
|
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
|   |   |
|   |
|   |
|
|   |   |   |   |   |   |
|   |   |
|
|
|   |   |   |   |   |   |   |
|
|
|   |
|   |
|
|   |   |
|
|   |   |
|   |   |
|
|   |   |
|
|
|   |
|
|   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Sequence |   |
Y | S | E | G | V | D | E | I | E | L | L | C | Q | R | R | A | L | E | A | F | D | L | D | P | A | Q | W | G | V | N | V | Q | P | Y | S | G | S | P | A | N | L | A | V | Y | T | A | L | L | Q | P | H | D | R | I | M | G | Y | K | L | N | P | K | T | G | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
|
|
|
|
| T |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
| T | T | T |  |  |  |  |
|
|
| S | S |  |  |  |  |  |  |  |  |  |  |  |  |
|
| S |
|  |  |
|
|
|
|
| B |
| T | T | T |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|  |  |  |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |
  |   |
131 | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . |
Predicted Secondary structure |   |
 |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
W | F | D | P | L | I | G | A | D | I | V | K | H | L | Q | P | N | T | K | I | V | F | L | E | S | P | G | S | I | T | M | E | V | H | D | V | P | A | I | V | A | A | V | R | S | V | V | P | D | A | I | I | M | I | D | N | T | W | A | . |
. |
. |
. |
. |
A | G | V | L | F | K | A | L | D | F | G | I | D | V | S | I |
Query Conservation |   |
  |   |
|   |   |
|   |   |   |
|   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |
|   |   |
|   |   |   |   |
|   |   |
|   |   |   |
|   |   |   |   |   |
|   |   |
|
|
|
|   |
|   |   | . | . | . | . | . |   |
|   |   |   |   |   |   |   |   |
|   |
|   |   |   |
Alig confidence |   |
. | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
Template Conservation |   |
. | . | . |   |
|
|   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |   |
|   | . |   |   |   |   |   |
|   |   |   |
|   |
|
|   |   |   |   | . | . |
|
|   |
|   |
|
|   |
|
|   |
|
|
|
|   |   |   |   |   |
|   |
|   |   | . |   |
|
|
|
|   |
Template Sequence |   |
. |
. |
. |
L | I | D | Y | N | Q | L | A | L | T | A | R | L | F | R | P | R | L | I | I | A | G | T | S | A | . |
Y | A | R | L | I | D | Y | A | R | M | R | E | V | C | D | E | V | . |
. |
K | A | H | L | L | A | D | M | A | H | I | S | G | L | V | A | A | K | V | I | P | S | P | F | K | . |
H | A | D | I | V | T |
Template Known Secondary structure |   |
. | . | . | S | B |
|  |  |  |  |  |  |  |  |  |  |  |
|
| S |  |  |  |  |
|
| S | S | . |
|
| S |
|
|
|  |  |  |  |  |  |  |  |  |  | T | . | . | T |
|  |  |  |  |  |
| G | G | G |  |  |  |  |  | T | T | S | S |
|
| G | G | G | . | T |
| S |  |  |  |
Template Predicted Secondary structure |   |
. | . | . |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
| . |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
| . | . |
|
|  |  |  |  |
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
187 | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | |
. | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | |
|
. | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | |
. | . | . | . | . | . |
  |
  |   |
206 | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 |
Predicted Secondary structure |   |
 |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Q | A | A | T | K | Y | L | V | G | H | S | D | A | M | I | G | T | A | V | C | N | A | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
R | C | W | E | Q | L | R | E | N | A | Y | L | M | G | Q | M | V | D | A | D | T | A | Y | I | T | S | R | G | L | R | T | L | G | V | R | L | R | Q | H | H | E | S | S |
Query Conservation |   |
  |
|   |
|
|   |   |   |
|   |   |   |   |   |
|
|   |
|   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |
|   |   |
|   |   |   |   |   |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|
|
|
|
|
|   |
|
|   | . | . | . |
|
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
| . | . | . | . | . | . | . | . |
|
|
|
|   |
|
|   |
|   |   |   |
Template Sequence |   |
T | T | T | H | K | T | L | R | G | A | R | . |
. |
. |
S | G | L | I | F | Y | R | K | G | V | K | A | V | D | P | K | T | G | R | E | I | P | Y | T | F | E | D | R | I | N | F | A | V | F | P | S | L | Q | G | G | P | H | N | H | A | I | . |
. |
. |
. |
. |
. |
. |
. |
A | A | V | A | V | A | L | K | Q | A | C | T |
Template Known Secondary structure |   |
 |  | S | S | G | G | G |
| S |
| S | . | . | . |
|  |  |  |  |  |  |
| S |  |  |  |  |  | T | T | T |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  | T | T | T | T |
|
| S |
|
|  |  |  |  | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  | S |
Template Predicted Secondary structure |   |
 |  |
|
|
|
|
|
|
|
|
| . | . | . |
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
260 | . | . | . | . | . | . | . | . | . | 270 | |
|
|
. | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
. | . | . | 320 | . | . | . | . | . | . | . | . |
  |
  |   |
271 | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | |
320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |
|  |  |  |  |
|
|
|
|  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
| . |
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | K | V | A | E | W | L | A | E | H | P | Q | V | A | R | V | N | H | P | A | L | P | G | S | K | G | H | E | F | W | K | R | D | F | T | G | S | S | G | L | F | S | F | V | L | K | K | K | L | . |
N | N | E | E | L | A | N | Y | L | D | N | F | S | L | F | S | M | A | Y | S | W | G | G | Y | E | S | L | I | L | A |
Query Conservation |   |
  |   |
|
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |   |   |   | . |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |
|   |
|   |   |   |
|
|   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |
|   |   |
|
|   |   |
|
|   |   |
|   |   |   |
|   |   |   |
|   |   |
|   |   | . | . | . |
|   |
|
|   |
|   |
|
|
|
|   |   |   |   |
|
|   |
|   |   |   |   |   |   |
|
|   |   |
|
|   |   |
|   |   |   |   |
|   |
|   |   |   |   |   |   |
Template Sequence |   |
P | M | F | R | E | Y | S | L | Q | V | L | K | N | A | R | A | M | A | D | A | L | L | E | R | G | Y | S | L | V | S | . |
. |
. |
G | G | T | D | N | H | L | V | L | V | D | L | R | P | K | G | L | D | G | A | R | A | E | R | V | L | E | L | V | S | I | T | A | N | K | N | T | C | P | G | D | R | S | A | I | T | P |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|  |  | G | G | . | . | . | G | S |
| S | S | S |  |  |  |  |  |
| T | T | T | T |
|
|  |  |  |  |  |  |  |  |  |  | T | T |  |  |
|  |  |  |
|
| T | T |
|
|
| S | S | S |
|
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
| . | . | . |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
329 | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | |
|
|
. | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . |
  |
  |   |
350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | |
|
|
|
. | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  | . | . | . | . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
N | Q | P | E | H | I | A | A | I | R | P | Q | G | E | I | D | F | S | G | T | L | I | R | L | H | I | G | . |
. |
. |
. |
L | E | D | V | D | D | L | I | A | D | L | D | A | G | F | A | R | I | V |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |
|
|
|
|   |
| . | . | . | . |
|
|   |   |   |
|
|
|   |
|
|   |   |
|
|   |   |
|   |
Alig confidence |   |
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|   |   |   |
|   |
|
|   |   |
|   |
|   |   |   |
|
|   |   |
|   |   |   |
|
Template Sequence |   |
G | G | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
L | R | L | G | A | P | A | L | T | S | R | Q | F | R | E | D | D | F | R | R | V | V | D | F | I | D | E | G | V |
Template Known Secondary structure |   |
S |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  | S |  |  |  |  |  | T | T |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|  |  |
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
406 | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . |
  |