|   |
40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
. | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| . | . | . | . | . | . | . | . |
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | A | K | K | H | A | T | R | N | R | A | N | G | E | L | F | Y | G | R | R | G | T | L | T | H | F | S | L | Q | Q | A | M | C | E | L | E | G | . |
. |
. |
. |
. |
. |
. |
. |
G | A | G | C | V | L | F | P | C | G | A | A | A | V | A | N | S | I | L | A | F | I | E | Q | G | D | H | V | L | M | T | N | T | A | Y |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |
|
|   |   |   |
|
|   |   |
|
|   |
|   |
| . | . | . | . | . | . | . | . |   |   |   |   |
|   |   |   |
|
|   |   |
|   |   |   |
|
|   |
|
|
|   |   |
|
|   |
|
|   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| . | . |   |   |   |   |
|   |   |   |
|
|   |
|
|
|   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |
|   |
|   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|   |   |   |
|   |
|
Template Sequence |   |
K | I | A | V | E | V | L | E | E | H | A | D | K | A | L | Q | Y | . |
. |
G | T | T | K | G | F | T | P | L | R | L | A | L | A | R | W | M | E | K | R | Y | D | I | P | M | S | K | V | E | I | M | T | V | A | G | S | Q | Q | A | L | D | L | I | G | R | V | F | L | N | P | G | D | P | I | V | V | E | A | P | T | Y |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  | S |  |  |  |  |  | S |
| . | . |
|
| S | S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
| T | T |
|  |  |  |  |  | S | S |  |  |  |  |  |  |  |  |  |  |  |  |
|
| T | T |
|  |  |  |  |  |  | S |
|
|
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |
|
|
|
|
|
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
63 | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | |
|
80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 |
  |
  |   |
112 | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
. | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | |
. | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  | . |  |  |
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
Query Sequence |   |
E | P | S | Q | D | F | C | S | K | I | L | S | K | L | G | V | T | T | S | W | F | D | P | L | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
I | G | A | D | I | V | K | H | L | Q | P | N | T | K | I | V | F | L | E | S | P | G | S | I | T | M | E | V | H | D | V | P | A | I | V | A | A | V | R | . |
S | V | V | P | D |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |
|   |   | . | . | . | . | . | . | . | . | . | . | . |
|   |   |   |
|   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |
|   |   |
|   |   |   |   |
|   |   |
|   |   |   |
|   | . |   |   |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   | . | . | . | . |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |
|
|
|
|   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |
Template Sequence |   |
L | A | A | I | Q | A | F | . |
. |
. |
. |
K | Y | Y | D | P | E | F | I | S | I | P | L | D | D | K | G | M | R | V | D | L | L | E | E | K | L | E | E | L | R | K | Q | G | K | R | V | K | I | V | Y | T | V | S | T | F | Q | N | P | A | G | V | T | M | S | V | D | R | R | K | K | L | L | E | L | A | N | E | Y | D |
Template Known Secondary structure |   |
 |  |  |  |  |  |  | . | . | . | . |  | T | T |
|
|  |  |  |  |  |  |  |  | T | T |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
|
|  |  |  |  |
|
| S | S |
| T | T | T |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  | . | . | . | . |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
141 | . | . | . | . | . | . | |
|
|
|
. | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . |
  |
  |   |
180 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | I | I | M | I | D | N | T | W | A | . |
. |
. |
. |
. |
. |
A | G | V | L | F | K | A | L | D | F | G | I | D | V | S | I | Q | A | A | T | K | Y | L | V | G | H | S | D | A | M | I | G | T | A | V | C | N | A | R | C | W | E | Q | L | R | E | N | A | Y | L | M | G | Q | M | V | D | A | D | T | A | Y | I | T | S |
Query Conservation |   |
  |   |
|
|
|
|   |
|   |   | . | . | . | . | . | . |   |
|   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |
|   |
|
|   |   |   |
|   |   |   |   |   |
|
|   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|
|   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
Template Sequence |   |
F | L | I | V | E | D | G | P | Y | S | E | L | R | Y | S | G | E | P | T | P | P | I | K | H | F | D | D | Y | G | R | V | I | Y | L | G | T | F | S | K | I | L | A | P | G | F | R | I | G | W | V | A | A | H | P | H | L | I | R | K | M | E | I | A | K | Q | S | I | D | L | C | T | N | T | F | G | Q | A | I | A | W |
Template Known Secondary structure |   |
|  |  |  |  |  |
| T | T | T | T |
| B |
| S | S |
|
|
|
|
| G | G | G | G |
| S | S | S |
|  |  |  |  |  |  | S | T | T | T | T |
| G | G | G |
|
|  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | S | S |
|
|  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
217 | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . |
  |
  |   |
254 | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . |
Predicted Secondary structure |   |
|
|  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  |  |  |  |
|
|
|
|  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
R | G | L | R | T | L | G | V | R | L | R | Q | H | H | E | S | S | L | K | V | A | E | W | L | A | E | H | P | Q | V | A | R | V | N | H | P | A | L | P | G | S | K | G | H | E | F | W | K | R | D | F | T | G | S | S | G | L | F | S | F | V | L | K | K | K | L | N | N | E | E | L | A | N | Y | L | D | N | F | S | L |
Query Conservation |   |
  |   |
|   |   |
|   |   |
|   |   |   |   |   |   |   |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . |
|   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   | . | . | . |   |   |   |
|   |   |
Template Sequence |   |
K | Y | V | E | N | G | Y | L | D | E | H | I | P | K | I | I | E | F | Y | K | P | R | R | D | A | M | L | E | A | L | E | E | Y | M | P | E | G | V | E | W | T | K | . |
. |
. |
. |
. |
. |
. |
. |
. |
P | E | G | G | M | F | V | R | V | T | L | P | E | G | I | D | T | K | L | M | . |
. |
. |
M | E | R | A | V | A |
Template Known Secondary structure |   |
 |  |  |  | T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| T | T |
|  |  |
|
| . | . | . | . | . | . | . | . | . |
| S | B | S | S |  |  |  |  |  |
|
| T | T |
|
| T | T | T | T | . | . | . |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
| . | . | . | . | . | . | . | . | . |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  | . | . | . |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
297 | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
. | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | |
|
|
. | 360 | . | . | . | . |
  |
  |   |
334 | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | |
|
|
. | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . |
Predicted Secondary structure |   |
|
|  |  |
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
| . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
F | S | M | A | Y | S | W | G | G | Y | E | S | L | I | L | A | N | Q | P | E | H | I | A | A | I | R | P | Q | G | E | I | D | F | S | G | T | L | I | R | L | H | I | G | L | . |
. |
. |
E | D | V | D | D | L | I | A | D | L | D | A | G | F | A | R | I | V |
Query Conservation |   |
  |   |
|   |   |
|   |
|   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |
|
|
|
|   |
|
| . | . | . |
|   |   |   |
|
|
|   |
|
|   |   |
|
|   |   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|
|   |
|   |
|
|   |   |
|   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |
|
|
|
|   |   |   |   |   |   |
|   |
|   |   |   |
|   |   |
|   |   |   |
|   |   |   |   |
Template Sequence |   |
K | G | V | A | Y | V | P | G | E | A | F | F | V | H | R | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
D | K | K | N | T | M | R | L | N | F | T | Y | V | P | E | E | T | I | R | E | G | V | R | R | L | A | E | T | I | K | E | E | M |
Template Known Secondary structure |   |
T | T |  |  |
|  |  | G | G | G | G | S | T | T |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
| S |  |  |  |  |  |
| S | S | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |
|  |  |  |
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
365 | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . |
  |