|   |
58 | . | 60 | . | . | . | |
. | . | . | . | . | . | 70 | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . |
Predicted Secondary structure |   |
|
|
|
|  |  | . |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
R | R | G | T | L | T | . |
H | F | S | L | Q | Q | A | M | C | E | L | E | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
G | G | A | G | C | V | L | F | P | C | G | A | A | A | V | A | N | S | I | L | A | F | I | E | Q | G | D | H | V | L | M | T | N | T | A | Y | E | P | S | Q | D | F | C | S | K | I |
Query Conservation |   |
|   |   |   |
|
| . |   |   |   |
|
|   |   |
|
|   |
|   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|   |   |   |   |
|   |   |   |
|
|   |   |
|   |   |   |
|
|   |
|
|
|   |   |
|
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
Template Conservation |   |
  |
|   |   |   |   |
|   |   |   |
|
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|   |
|   |   |   |
|
|   |   |   |   |   |   |
|   |   |   |
|
|   |
|
|
|   |   |
|   |
|   |   |   |   |   |   |   | . | . | . |
Template Sequence |   |
Q | Y | S | P | S | A | G | I | P | E | L | L | S | W | L | K | Q | L | Q | I | K | L | H | N | P | P | T | I | H | Y | P | P | S | Q | G | Q | M | D | L | C | V | T | S | G | S | Q | Q | G | L | C | K | V | F | E | M | I | I | N | P | G | D | N | V | L | L | D | E | P | A | Y | S | G | T | L | Q | S | L | . |
. |
. |
Template Known Secondary structure |   |
S |
|
|
| T | T |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
| T | T | T | T | S |
| G | G | G | T |
|  |  |  |  |  |  | S | S |  |  |  |  |  |  |  |  |  |  |  |  |
|
| T | T |
|  |  |  |  |  | S | S |
|
|  |  |  |  |  |  |  | . | . | . |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
73 | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | |
|
|
  |
  |   |
122 | . | . | . | . | . | . | . | 130 | . | . | . | . | . | |
|
|
|
. | . | . | . | 140 | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | 150 | . | . | . | . | |
. | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | |
. | . | . | . | . | 180 | . | . | . |
Predicted Secondary structure |   |
 |  |  |
|
|
|  |  |  |  |
|
|
|
| . | . | . | . |
|  |  |  |  |  |  |  |
|
| . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|  |  |  |  | . |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  | . |  |  |
|
|
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | S | K | L | G | V | T | T | S | W | F | D | P | L | . |
. |
. |
. |
I | G | A | D | I | V | K | H | L | Q | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
P | N | T | K | I | V | F | L | E | . |
S | P | G | S | I | T | M | E | V | H | D | V | P | A | I | V | A | A | V | R | . |
S | V | V | P | D | A | I | I | M |
Query Conservation |   |
  |   |   |   |
|
|   |   |   |   |   |
|   |   | . | . | . | . |
|   |   |   |
|   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . |   |   |
|   |   |
|   |   |   | . |   |   |   |
|   |   |
|   |   |   |   |
|   |   |
|   |   |   |
|   | . |   |   |   |   |
|   |   |
|
|
Alig confidence |   |
. |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. |   |   |   |
|   |   |   |   |   |
|   |   |   |   |   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |
|
|
Template Sequence |   |
. |
H | P | L | G | C | N | I | I | N | V | A | S | D | E | S | G | I | V | P | D | S | L | R | D | I | L | S | R | W | K | P | E | D | A | K | N | P | Q | K | N | T | P | K | F | L | Y | T | V | P | N | G | N | N | P | T | G | N | S | L | T | S | E | R | K | K | E | I | Y | E | L | A | R | K | Y | D | F | L | I | I |
Template Known Secondary structure |   |
. | G | G | G | T |
|  |  |  |  |  |
|  |  | T | T |  |  |
|  |  |  |  |  |  |  |  | T | T | S |
| G | G | G | G | S |
| G | G | G |
|
|
| S |  |  |  |  |
|
| S | S |
| T | T | T |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|  |  |  |
Template Predicted Secondary structure |   |
. |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . |
  |
  |   |
184 | . | . | . | . | . | 190 | . | . | . | . | . | . | . | |
|
|
|
|
|
. | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
I | D | N | T | W | A | A | G | V | L | F | K | A | L | . |
. |
. |
. |
. |
. |
D | F | G | I | D | V | S | I | Q | A | A | T | K | Y | L | V | G | H | S | D | A | M | I | G | T | A | V | C | N | A | R | C | W | E | Q | L | R | E | N | A | Y | L | M | G | Q | M | V | D | A | D | T | A | Y | I | T | S | R | G | L | R |
Query Conservation |   |
|
|   |
|   |   |   |
|   |   |   |   |   |   | . | . | . | . | . | . |   |   |
|   |
|   |   |   |   |
|   |
|
|   |   |   |
|   |   |   |   |   |
|
|   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |
|   |
|
| . |   |   |   |
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |
Template Sequence |   |
E | D | D | P | Y | Y | F | L | Q | F | N | K | F | R | V | P | T | F | L | S | M | D | V | D | G | R | V | I | R | A | D | S | F | S | I | . |
I | S | S | G | L | R | I | G | F | L | T | G | P | K | P | L | I | E | R | V | I | L | H | I | Q | V | S | T | L | H | P | S | T | F | N | Q | L | M | I | S | Q | L | L | H |
Template Known Secondary structure |   |
 |  |
| T | T | T | T |
| B | S | S | S | S |
|
|
|
| S | G | G | G |
| S | S | S |
|  |  |  |  |  |  |
|
|
| . |
|
| S | T | T |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | T | T |
| S | S |
|  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
| . |
|
|
|
|
|
|
|
|  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
229 | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | |
. | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . |
  |
  |   |
258 | |
|
. | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . |
Predicted Secondary structure |   |
| . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  |  |  |  |
|
|
|
|  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
Query SS confidence |   |
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
T | . |
. |
L | G | V | R | L | R | Q | H | H | E | S | S | L | K | V | A | E | W | L | A | E | H | P | Q | V | A | R | V | N | H | P | A | L | P | G | S | K | G | H | E | F | W | K | R | D | F | T | G | S | S | G | L | F | S | F | V | L | K | K | K | L | N | N | E | E | L | A | N | Y | L | D | N | F | S | L | F | S |
Query Conservation |   |
  | . | . |
|   |   |
|   |   |   |   |   |   |   |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
Alig confidence |   |
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |   |   |   |   |   | . | . | . | . | . | . | . | . |   |   |   |   |   |
|   |   |
|   |
|   |   |
|   |
|   |   |   |   |   |   |   | . | . |   |   |   |   |   |   |
|   |   |   |
|
Template Sequence |   |
E | W | G | E | E | G | F | M | A | H | V | D | R | V | I | D | F | Y | S | N | Q | K | D | A | I | L | A | A | A | D | K | W | L | T | G | L | . |
. |
. |
. |
. |
. |
. |
. |
A | E | W | H | V | P | A | A | G | M | F | L | W | I | K | V | K | G | I | N | D | V | K | . |
. |
E | L | I | E | E | K | A | V | K | M | G |
Template Known Secondary structure |   |
 |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | B | T | T | . | . | . | . | . | . | . | . |  |  |  |
|
|
| S | B | S | S |  |  |  |  |  |  | T | T |
| S |
| S |  | . | . |  |  |  |  | T |  |  |  |  | T | T |
Template Predicted Secondary structure |   |
 |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
| . | . | . | . | . | . | . | . |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  | . | . |  |  |  |  |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
309 | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | |
|
|
|
|
|
|
|
. | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | |
|
. | . | 370 | . | . | . | . | . | . | . | . |
  |
  |   |
336 | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | |
|
|
. | . | . | . | . | . | 390 | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  | . | . | . |  |  |  |  |  |  |  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
M | A | Y | S | W | G | G | Y | E | S | L | I | L | A | N | Q | P | E | H | I | A | A | I | R | P | Q | G | E | I | D | F | S | G | T | L | I | R | L | H | I | G | L | E | D | V | D | D | L | . |
. |
. |
I | A | D | L | D | A | G | F | A | R | I | V |
Query Conservation |   |
|   |   |
|   |
|   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |
|
|
|
|   |
|
|
|   |   |   |
|
| . | . | . |
|   |
|
|   |   |
|
|   |   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |
|   |
|
|   |   |
|   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |
|
|
|   |   |   |   |   |   |   |
|   |
|   |   |   |
|   |   |
|   |   |   |
|   |
|   |
|
Template Sequence |   |
V | L | M | L | P | G | N | A | F | Y | V | D | S | S | A | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
P | S | P | Y | L | R | A | S | F | S | S | A | S | P | E | Q | M | D | V | A | F | Q | V | L | A | Q | L | I | K | E | S | L |
Template Known Secondary structure |   |
|
|
|  |  | G | G | G | G | S | S | S | T | T | S | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|  |  |  |  |  |
| S | S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Template Predicted Secondary structure |   |
|  |  |  |  |
|  |  |  |
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
379 | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . |
  |