Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP0AEX3
DateThu Jan 5 11:24:31 GMT 2012
Unique Job ID0668d265a5320346

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template d1pw4a_
Top template information
Fold:MFS general substrate transporter
Superfamily:MFS general substrate transporter
Family:Glycerol-3-phosphate transporter
Confidence and coverage
Confidence:100.0% Coverage: 97%
420 residues ( 97% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MAESTVTADSKLTSSDTRRRIWAIVGASSGNLVEWFDFYVYSFCSLYFAHIFFPSGNTTT
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   .........70.........80.........90.........100.........110.........120
Sequence  QLLQTAGVFAAGFLMRPIGGWLFGRIADKHGRKKSMLLSVCMMCFGSLVIACLPGYETIG
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   .........130.........140.........150.........160.........170.........180
Sequence  TWAPALLLLARLFQGLSVGGEYGTSATYMSEVAVEGRKGFYASFQYVTLIGGQLLALLVV
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   .........190.........200.........210.........220.........230.........240
Sequence  VVLQHTMEDAALREWGWRIPFALGAVLAVVALWLRRQLDETSQQETRALKEAGSLKGLWR
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   .........250.........260.........270.........280.........290.........300
Sequence  NRRAFIMVLGFTAAGSLCFYTFTTYMQKYLVNTAGMHANVASGIMTAALFVFMLIQPLIG
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   .........310.........320.........330.........340.........350.........360
Sequence  ALSDKIGRRTSMLCFGSLAAIFTVPILSALQNVSSPYAAFGLVMCALLIVSFYTSISGIL
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   .........370.........380.........390.........400.........410.........420
Sequence  KAEMFPAQVRALGVGLSYAVANAIFGGSAEYVALSLKSIGMETAFFWYVTLMAVVAFLVS
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   .........430..
Sequence  LMLHRKGKGMRL
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???????
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Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 1pw4 chain A

3D model

Region: 1 - 431
Aligned: 420
Modelled: 425
Confidence: 100.0%
Identity: 10%
Fold: MFS general substrate transporter
Superfamily: MFS general substrate transporter
Family: Glycerol-3-phosphate transporter

Phyre2

PDB 3o7p chain A

3D model

Region: 18 - 427
Aligned: 392
Modelled: 406
Confidence: 100.0%
Identity: 11%
PDB header:transport protein
Chain: A: PDB Molecule:l-fucose-proton symporter;
PDBTitle: crystal structure of the e.coli fucose:proton symporter, fucp (n162a)

Phyre2

PDB 1pv7 chain A

3D model

Region: 17 - 432
Aligned: 403
Modelled: 410
Confidence: 100.0%
Identity: 13%
Fold: MFS general substrate transporter
Superfamily: MFS general substrate transporter
Family: LacY-like proton/sugar symporter

Phyre2

PDB 2gfp chain A

3D model

Region: 24 - 416
Aligned: 368
Modelled: 393
Confidence: 100.0%
Identity: 13%
PDB header:membrane protein
Chain: A: PDB Molecule:multidrug resistance protein d;
PDBTitle: structure of the multidrug transporter emrd from2 escherichia coli

Phyre2

PDB 2xut chain C

3D model

Region: 38 - 423
Aligned: 377
Modelled: 386
Confidence: 99.9%
Identity: 11%
PDB header:transport protein
Chain: C: PDB Molecule:proton/peptide symporter family protein;
PDBTitle: crystal structure of a proton dependent oligopeptide (pot)2 family transporter.

Phyre2

PDB 2g9p chain A

3D model

Region: 82 - 95
Aligned: 14
Modelled: 14
Confidence: 31.3%
Identity: 50%
PDB header:antimicrobial protein
Chain: A: PDB Molecule:antimicrobial peptide latarcin 2a;
PDBTitle: nmr structure of a novel antimicrobial peptide, latarcin 2a,2 from spider (lachesana tarabaevi) venom

Phyre2

PDB 2jln chain A

3D model

Region: 2 - 112
Aligned: 111
Modelled: 111
Confidence: 9.7%
Identity: 9%
PDB header:membrane protein
Chain: A: PDB Molecule:mhp1;
PDBTitle: structure of mhp1, a nucleobase-cation-symport-1 family2 transporter

Phyre2

PDB 3hd6 chain A

3D model

Region: 7 - 241
Aligned: 220
Modelled: 235
Confidence: 9.7%
Identity: 9%
PDB header:membrane protein, transport protein
Chain: A: PDB Molecule:ammonium transporter rh type c;
PDBTitle: crystal structure of the human rhesus glycoprotein rhcg

Phyre2
1

d1pw4a_
2

c3o7pA_
3

d1pv7a_
4

c2gfpA_
5

c2xutC_
6

c2g9pA_
7

c2jlnA_
8

c3hd6A_



Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1d1pw4a_



100.0 10 Fold:MFS general substrate transporter
Superfamily:MFS general substrate transporter
Family:Glycerol-3-phosphate transporter
2c3o7pA_



100.0 11 PDB header:transport protein
Chain: A: PDB Molecule:l-fucose-proton symporter;
PDBTitle: crystal structure of the e.coli fucose:proton symporter, fucp (n162a)
3d1pv7a_



100.0 13 Fold:MFS general substrate transporter
Superfamily:MFS general substrate transporter
Family:LacY-like proton/sugar symporter
4c2gfpA_



100.0 13 PDB header:membrane protein
Chain: A: PDB Molecule:multidrug resistance protein d;
PDBTitle: structure of the multidrug transporter emrd from2 escherichia coli
5c2xutC_



99.9 11 PDB header:transport protein
Chain: C: PDB Molecule:proton/peptide symporter family protein;
PDBTitle: crystal structure of a proton dependent oligopeptide (pot)2 family transporter.
6c2g9pA_



31.3 50 PDB header:antimicrobial protein
Chain: A: PDB Molecule:antimicrobial peptide latarcin 2a;
PDBTitle: nmr structure of a novel antimicrobial peptide, latarcin 2a,2 from spider (lachesana tarabaevi) venom
7c2jlnA_



9.7 9 PDB header:membrane protein
Chain: A: PDB Molecule:mhp1;
PDBTitle: structure of mhp1, a nucleobase-cation-symport-1 family2 transporter
8c3hd6A_



9.7 9 PDB header:membrane protein, transport protein
Chain: A: PDB Molecule:ammonium transporter rh type c;
PDBTitle: crystal structure of the human rhesus glycoprotein rhcg

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Transmembrane helix prediction 

Transmembrane helices have been predicted in your sequence to adopt the topology shown below



Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0