|   |
1 | . | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | |
|
. | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Predicted Secondary structure |   |
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
| . | . |
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Sequence |   |
M | L | N | T | L | I | V | G | A | S | G | Y | A | G | A | E | L | V | T | Y | V | N | R | H | P | . |
. |
H | M | N | I | T | A | L | T | V | S | A | Q | S | N | D | A | G | K | L | I | S | D | L | H | P | Q | L | K | G | I | V | D | L | P | L | Q | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Conservation |   |
|
|
|
|
|
|
|
|
|
|
|   |
|
|   |   |
|
|
|
|
|   |   |
|
| . | . |   |   |   |
|   |   |
|   |   |   |
|
|   |   |   |
|
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
  |
|
|
|
|
|
|
|
| . |
|
|
|
|
|   |
|
|
|   |
|   |   |   |   |   |   |   |
|   |
|
|
|
|
|   |   |   |   |   |   |   |   |
|   |
|
|   |   |
|
|   |   |
|   |   |   |   |   |
|   |   |   |   |   |   |
|   |
|   |
|   |   |
|   |
|   |   |   |   |
Template Sequence |   |
T | I | R | V | A | I | N | G | F | . |
G | R | I | G | R | N | F | L | R | C | W | F | G | R | Q | N | T | D | L | E | V | V | A | I | N | N | T | S | D | A | R | T | A | A | H | L | L | E | Y | D | S | V | L | G | R | F | N | A | D | I | S | Y | D | E | N | S | I | T | V | N | G | K | T | M | K | I | V | C | D | R |
Template Known Secondary structure |   |
|  |  |  |  |  |  |
|
| . | S |  |  |  |  |  |  |  |  |  |  |  | T |
| S | S |
| S |  |  |  |  |  |  |  |
| S | S |
|  |  |  |  |  |  |  |  |  |  |  | T | T | T |  |  |
|
| S |
|  |  |  |  | T | T |  |  |  |  | T | T |  |  |  |  |  |  |
|
| S |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |
|
| . |
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
2 | . | . | . | . | . | . | . | 10 | |
. | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 |
  |
  |   |
62 | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . |
Predicted Secondary structure |   |
 |
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|  |  |
|
|
|
|
|  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
P | M | S | D | I | S | E | F | S | P | G | V | D | V | V | F | L | A | T | A | H | E | V | S | H | D | L | A | P | Q | F | L | E | A | G | C | V | V | F | D | L | S | G | A | F | R | V | N | D | A | T | F | Y | E | K | Y | Y | G | F | T | H | Q | Y | P | E | L | L | E | Q | A | A | Y | G | L | A | E | W | C | G | N |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|
|   |
|   |   |
|
|   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|
|
|
|   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |   |
|   |
|   |   |   |
|
|
|
|
|
|
|   |
|
|   |   |   |   |   |   |   |
|   |   |
|
|   |   |
|
|
|   |
|
|
| . |
|
|
|   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |
|   |
|   |
|
|   |
|
|
|   |   |
Template Sequence |   |
N | P | L | N | L | P | W | K | E | W | D | I | D | L | V | I | E | S | T | G | V | F | V | T | A | E | G | A | S | K | H | I | Q | A | G | A | K | K | V | L | I | . |
T | A | P | G | K | A | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
E | G | V | G | T | Y | V | I | G | V | N | D | S |
Template Known Secondary structure |   |
| G | G | G |
|
| T | T | T | T | T |
|
|  |  |  |  |
| S | S | S |
|
| B |  |  |  |  |  |  |  |  |  | T | T |
| S |  |  |  |  | . | S | S |
|
| B | S | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | S | S |
|  |  |
|
| T | T | T | T | G | G |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  | . |
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|  |  |  |  |
|
|
|  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
81 | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | |
. | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | 130 | . | . | . | . | . | . | . | . | . | 140 |
  |
  |   |
142 | . | . | . | . | |
|
. | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | |
|
|
. | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |
|
|
| . | . |
|  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
| . | . | . |
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|  |  |
|
|
|
|  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
K | L | K | E | A | . |
. |
N | L | I | A | V | P | G | C | Y | P | T | A | A | Q | L | A | L | K | P | L | I | D | A | D | L | L | D | L | N | Q | W | P | V | I | N | A | T | S | G | V | S | . |
. |
. |
G | A | G | R | K | A | A | I | S | N | S | F | C | E | V | S | L | Q | P | Y | G | V | F | T | H | R | H | Q | P |
Query Conservation |   |
  |
|   |   |   | . | . |   |
|
|
|
|
|   |
|   |
|
|   |   |   |
|   |
|   |
|
|   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |
|   |
|
|   |
| . | . | . |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |   |   |
|
|   |   |   |
Alig confidence |   |
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |
|
|
|
|   |
|
|
|
|   |   |
|
|
|   |
|
|   |
|   |   |   |
|
|
|   |   |   |   |
|
|
|
|
|
|   |
|   |   |
|   |   |   |
|   |   |   |   |
|   |
|   |   |
|   |   |   |   |
|
|
|
|   |   |
|
|   |
|
|   |
|   |
Template Sequence |   |
E | Y | R | H | E | D | F | A | V | I | S | N | A | S | C | T | T | N | C | L | A | P | V | A | K | V | L | H | D | N | F | G | I | I | K | G | T | M | T | T | T | H | S | Y | T | L | D | Q | R | I | L | D | A | S | H | R | D | L | R | R | A | R | A | A | A | V | N | I | V | P | T | T | T | G | A | A | K | A | V | A |
Template Known Secondary structure |   |
G |
|
| T | T | T |
| S |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |
|
| T | T | S |
| S | S | S |
|
|
| S | S | T | T | T | T | S |
| G | G | G |
|
|  |  |  |
|
|
|  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |
|
|
|
|
|
|  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
141 | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 |
  |
  |   |
217 | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | |
|
. | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | |
|
|
Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
| . | . |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|  |  |  |  | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
Query Sequence |   |
E | I | A | T | H | L | G | A | D | V | I | F | T | P | H | L | G | N | F | P | R | G | I | L | E | T | I | T | C | R | L | K | S | G | V | T | Q | A | Q | V | A | Q | V | L | Q | Q | A | Y | A | H | K | P | . |
. |
L | V | R | L | Y | D | K | G | V | P | A | L | K | N | V | V | G | L | P | F | C | D | I | . |
. |
. |
Query Conservation |   |
|
|   |   |   |
|   |   |   |
|   |   |
|   |   |
|
|
|
|   |   |
|   |   |   |
|
|   |
|   |   |   |   |   |
|   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   | . | . |   |
|   |   |   |   |   |   |   |
|   |   |   |   |
|   |
|   |   |   |   |   |
| . | . | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
| . | . | . |
Template Conservation |   |
  |
|
|
|   |
|   |
|
|
|   |   |   |
|
|
|
|
|
|   |   |   |
|   |   |
|
|   |
|   |   |   |   |   |   |   |   |
|
|
|   |   |   |
|
|   |
|   |   |   |   |
|   |
|
|
|   |   |   |   |   |   |   |
|
| . |   |
|   |   |   |   |   |   |
|   |
|   |
|   |
Template Sequence |   |
L | V | I | P | E | L | K | G | K | L | N | G | I | A | L | R | V | P | T | P | N | V | S | V | V | D | L | V | V | Q | V | E | K | P | T | I | T | E | Q | V | N | E | V | L | Q | K | A | S | Q | T | T | M | K | G | I | I | K | Y | S | D | L | P | L | V | S | . |
S | D | F | R | G | T | D | E | S | S | I | V | D | S |
Template Known Secondary structure |   |
 |  | S | G | G | G | T | T | S |  |  |  |  |  |  |  |  | S |
| S | S |
|  |  |  |  |  |  |  |  |  | S | S |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | T | T | T | T |  |  |  |  |
| S |
|
|
| G | . | G | G | G | T | T |
|
| S | S |  |  |  |  | G |
Template Predicted Secondary structure |   |
 |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |
|
|
|
|
|  |  |  | . |  |
|
|
|
|
|
|
|
|  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
221 | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | |
. | . | . | . | 290 | . | . | . | . | . | . | . | . | . |
  |
  |   |
|
|
292 | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . |
Predicted Secondary structure |   |
. | . |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
G | F | A | V | Q | G | E | H | L | I | I | V | A | T | E | D | N | L | L | K | G | A | A | A | Q | A | V | Q | C | A | N | I | R |
Query Conservation |   |
. | . |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|
|
|   |
|
|
|
|
|   |
|
|
|   |
|
|
|   |
Alig confidence |   |
. | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|
|
|
|   | . |
|
|
|   |
|   |   |
|   |   |   |   |   |
Template Sequence |   |
S | L | T | L | V | M | D | G | D | L | V | K | V | I | A | W | Y | D | N | E | W | . |
G | Y | S | Q | R | V | V | D | L | A | E | L | A |
Template Known Secondary structure |   |
G | G |
|  |  |  | T | T | T |  |  |  |  |  |  |  |  |
| T | T |  | . |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|  | . |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | |
. | . | . | . | . | . | . | . | . | 330 | . | . | . |
  |