Secondary structure and disorder prediction

1

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10

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20

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30

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40

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50

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60

Sequence

M

K

R

L

L

I

L

T

A

L

L

P

F

V

G

F

A

Q

P

I

N

T

L

N

N

P

N

Q

P

G

Y

Q

I

P

S

Q

Q

R

M

Q

T

Q

M

Q

T

Q

Q

I

Q

Q

K

G

M

L

N

Q

Q

L

K

T

Secondary structure

SS confidence

Disorder

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Disorder confidence

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70

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80

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90

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100

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110

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120

Sequence

Q

T

Q

L

Q

Q

Q

H

L

E

N

Q

I

N

N

N

S

Q

R

V

L

Q

S

Q

P

G

E

R

N

P

A

R

Q

Q

M

L

P

N

T

N

G

G

M

L

N

S

N

R

N

P

D

S

S

L

N

Q

Q

H

M

L

Secondary structure

SS confidence

Disorder

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Disorder confidence

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130

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140

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Sequence

P

E

R

R

N

G

D

M

L

N

Q

P

S

T

P

Q

P

D

I

P

L

K

T

I

G

P

Secondary structure

SS confidence

Disorder

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Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 3awf chain C Region: 5 - 38 Aligned: 34 Modelled: 34 Confidence: 7.9% Identity: 21% PDB header:hydrolase, membrane protein Chain: C: PDB Molecule:voltage-sensor containing phosphatase; PDBTitle: crystal structure of pten-like domain of ci-vsp (236-576) Phyre2 PDB 3aa6 chain C Region: 22 - 34 Aligned: 13 Modelled: 13 Confidence: 6.3% Identity: 46% PDB header:protein binding Chain: C: PDB Molecule:23mer peptide from cd2-associated protein; PDBTitle: crystal structure of actin capping protein in complex with the cp-2 binding motif derived from cd2ap Phyre2 1 c3awfC_ 2 c3aa6C_

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c3awfC_ 7.9 21 PDB header:hydrolase, membrane protein Chain: C: PDB Molecule:voltage-sensor containing phosphatase; PDBTitle: crystal structure of pten-like domain of ci-vsp (236-576) 2 c3aa6C_ 6.3 46 PDB header:protein binding Chain: C: PDB Molecule:23mer peptide from cd2-associated protein; PDBTitle: crystal structure of actin capping protein in complex with the cp-2 binding motif derived from cd2ap

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0