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Job DescriptionP0AD27
Confidence100.00%DateWed Jan 25 15:20:24 GMT 2012
Rank19Aligned Residues253
% Identity16%Templatec2xrgA_
PDB info PDB header:hydrolaseChain: A: PDB Molecule:ectonucleotide pyrophosphatase/phosphodiesterase family PDBTitle: crystal structure of autotaxin (enpp2) in complex with the2 ha155 boronic acid inhibitor
Resolution3.20 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   238.240.........250.........260.........270........ .280.........290.........300 .........310...
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Query Sequence  NPDAVSVQYPLSELRYRDMGTGQNVLLITVDGLNYSRFEKQ. . . MPALAGFAEQNISFTRHMSSGN. TTDNGIFGLFYGI
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Template Sequence  DDDCEEIKVP. . . . ECPAGFVRPPLIIFSVDGFRASYMKKGSKVMPNIEKLRSCGTHAPYMRPVYPTKTFPNLYTLATGL
Template Known Secondary structure  GS





S
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TT
SS

T

GGGGGS
TTTSS
S


SS
S
S
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   145....150.... .....160.........170.........180.........190.........200.........210.........220
 
   314.....320........ .330.........340.........350.........360.........370.
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Query Sequence  SPSYMDGILSTRTPA. . . . . . . . . . . . . . . . . . . . . . ALITALNQQGYQLGLFSSDGFTSPLYRQALLSDFSMPSVRTQS
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Template Sequence  YPESHGIVGNSMYDPVFDASFHLRGREKFNHRWWGGQPLWITATKQGVRAGTFFWSV. . . . . . . . . . . . . . . . . . . . SIP
Template Known Secondary structure 
S


SSTTTT
SSSSGGG
TTS

S

TTT

B





T....................TS
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   221........230.........240.........250.........260.........270....... ..280
 
   372.......380.........390.........400.........410.........420.........430.........440.........450.
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Query Sequence  DEQTATQWINWLGRYAQEDNRWFSWVSFNGTNIDDSNQQAFARKYSRAAGNVDDQINRVLNALRDSGKLDNTVVIITAGR
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Template Sequence  HERRILTILQWL. SLPDNERPSVYAFYSEQPDFSGHKYGPFGPEMTNPLREIDKTVGQLMDGLKQLRLHRCVNVIFVGDH
Template Known Secondary structure  T.TS
TTT

S
TT
GGGTT
TTT
S
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   281........290.. .......300.........310.........320.........330.........340.........350.........
 
   452
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Query Sequence  G. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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Template Sequence  GMEDVTCDRTEFLSNYLTNVDDITLVPGTLGRIRAKYDPKTIIAALTCKKPDQHFKPYMKQHLPKRLHYANNRRIEDIHL
Template Known Secondary structure 



SSSGGGT
S

TT
BS


TTSS
STT

GGGS
GGG


SSTTS
S
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   360.........370.........380.........390.........400.........410.........420.........430.........
 
   453......460.........470.........480.........490.........500.........510......
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Query Sequence  . . . . . . . . . IPLSEEEETFDWSHGHLQVPLVIHWPGTPAQRINALTDHTDLMTTLMQRLLHVSTPASEYSQGQ
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Template Sequence  LVDRRWHVARKPFQGDHGFDNKVNSMQTVFVGYGPTFKYRTKVPPFENIELYNVMC. DLLGLKPAPNNGTHGS
Template Known Secondary structure 
TT
S





S
TT
GGG
B
SSSB
SS
B


GGG.T



S
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TTT
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   446...450.........460.........470.........480.........490.........500. ........510.......
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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