Job Description P13009 Confidence 41.48% Date Thu Jan 5 11:33:23 GMT 2012 Rank 307 Aligned Residues 169 % Identity 12% Template c2cw6B_ PDB info PDB header:lyase Chain: B: PDB Molecule:hydroxymethylglutaryl-coa lyase, mitochondrial; PDBTitle: crystal structure of human hmg-coa lyase: insights into2 catalysis and the molecular basis for3 hydroxymethylglutaric aciduria Resolution 2.10 Å

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		379	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.			.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.
Predicted Secondary structure																																			.	.
Query SS confidence																																			.	.
Query Sequence		K	Y	S	E	A	L	D	V	A	R	Q	Q	V	E	N	G	A	Q	I	I	D	I	N	M	D	E	G	M	L	D	A	E	A	.	.	A	M	V	R	F	L	N	L	I	A	G	E	P	D	I	A	R	V	P	I	M	I	D	S	S	K	W	D	V	I	E	K	G	L	K	C	I	Q	G	K	G	I	V	N	S
Query Conservation																																			.	.
Alig confidence																																			.	.												.	.	.																							.	.
Template Conservation																																																.	.	.																							.	.
Template Sequence		S	T	P	V	K	I	K	L	I	D	M	L	S	E	A	G	L	S	V	I	E	T	T	S	F	V	S	P	K	W	V	P	Q	M	G	D	H	T	E	V	L	K	G	I	Q	K	.	.	.	F	P	G	I	N	Y	P	V	L	T	P	N	L	K	G	F	E	A	A	V	A	A	.	.	G	A	K	E	V	V	I
Template Known Secondary structure																T	T		S										T	T	T		G	G	G	T	T								S			.	.	.		T	T		B							S										T	.	.	T		S
Template Predicted Secondary structure																																																.	.	.																							.	.
Template SS confidence
		52	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.				.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.			120	.	.	.	.	.	.
																457	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.
Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	I	S	M	K	E	G	V	D	A	F	I	H	H	A	K	L	L	R	R	Y	G	A	A	V	V	V	M	A	F	D	E	Q	G	Q	A	D	T	R	A	R	K	I	E	I	C	R	R	A	Y	K	I	L	T	E	E	V	G	F	P	P	E	D	I	I	F	D
Query Conservation		.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.																																																					.						.	.	.	.	.	.	.
Template Conservation																																																																				.						.	.	.	.	.	.	.
Template Sequence		F	G	A	A	S	E	L	F	T	K	K	N	I	N	C	S	I	E	E	S	F	Q	R	F	D	A	I	L	K	A	A	Q	S	A	N	I	S	V	R	G	Y	V	S	C	A	L	G	C	P	Y	E	G	K	I	S	P	A	K	V	A	E	V	T	K	K	F	.	Y	S	M	G	C	.	.	.	.	.	.	.	Y
Template Known Secondary structure					S									T	S	S		T	T	T															T	T									S	T	T		B	T	T	T	B	S														.			T	T		.	.	.	.	.	.	.	S
Template Predicted Secondary structure																																																																				.						.	.	.	.	.	.	.
Template SS confidence
		127	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.		.	.	.	.	.								.
		523	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		P	N	I	F	A	V	A	T	G	I	E	E	H	N	N	Y	A	Q	D	F	I	G	A	C	E	D	I	K	R	E	L	P	H	A	L	I	S	G	G	V	S	N
Query Conservation
Alig confidence												.	.	.	.
Template Conservation												.	.	.	.
Template Sequence		E	I	S	L	G	D	T	I	G	V	.	.	.	.	G	T	P	G	I	M	K	D	M	L	S	A	V	M	Q	E	V	P	L	A	A	L	A	V	H	C	H	D
Template Known Secondary structure								T	T			.	.	.	.																	S		G	G	G						B
Template Predicted Secondary structure												.	.	.	.
Template SS confidence
		199	200	.	.	.	.	.	.	.	.					.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
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