|   |
1 | . | . | . | . | . | . | . | . | 10 | . | . | . | |
|
|
. | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | |
|
|
|
. | . | . | . | 70 | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |  |
|
|
|
|
|
| . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
| . | . | . | . |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
Query Sequence |   |
M | I | V | A | F | C | L | Y | K | Y | F | P | F | . |
. |
. |
G | G | L | Q | R | D | F | M | R | I | A | S | T | V | A | A | R | G | H | H | V | R | V | Y | T | Q | S | W | E | G | D | C | P | K | A | F | E | L | I | Q | V | P | V | K | S | H | T | N | H | G | R | N | . |
. |
. |
. |
A | E | Y | Y | A | W | V | Q |
Query Conservation |   |
|
|
|   |   |
|   |   |   |   |   |
|   | . | . | . |
|
|   |   |   |   |   |   |   |
|
|   |   |
|   |   |   |
|   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . |   |   |   |   |   |   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|
|   |   |
|
|   |   |
|   |   |   |   |   |   |
|
|   |   |
|   |
| . |   |
|
|   |   |
|   |   |   |
|   |   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
K | R | L | N | L | L | V | P | S | I | N | Q | E | H | X | F | G | G | I | S | T | A | L | . |
K | L | F | E | Q | F | D | N | K | K | F | K | K | R | I | I | L | T | D | A | T | P | N | P | K | D | L | Q | S | F | K | S | F | K | Y | V | X | P | E | E | D | K | D | F | A | L | Q | I | V | P | F | N | D | R | Y | N |
Template Known Secondary structure |   |
|  |  |  |  |  |  | S |
|
|
| G | G | G |
| S |  |  |  |  |  |  |  | . |  |  |  | T | T | S |
| T | T | T |
|  |  |  |  |  |  | S | S |
|
|
|
|  |  |  |  | G | G | G | T | T | S |  |  |
|
| T | T |
|
|
|
|
| S |  |  |  |  |  |
| S |
|
| T | T |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  | . |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
47 | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | |
70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . |
  |
  |   |
74 | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | |
|
|
|
|
|
. | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|  |  |  |
|
|
|
|
|  | . | . | . | . | . | . |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
N | H | L | K | E | H | P | A | D | R | V | V | G | F | N | K | M | P | . |
. |
. |
. |
. |
. |
G | L | D | V | Y | F | A | A | D | V | C | Y | A | E | K | V | A | Q | E | K | G | F | L | Y | R | L | T | S | R | Y | R | H | Y | A | A | F | E | R | A | T | F | E | Q | G | K | S | T | K | L | M | M | L | T | D | K | Q |
Query Conservation |   |
  |   |
|   |   |   |   |   |
|   |
|   |   |   |   |   |   |   | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
Template Sequence |   |
R | T | I | P | V | A | K | H | D | I | F | I | A | T | A | W | W | T | A | Y | A | A | Q | R | I | V | S | W | Q | S | D | T | Y | G | I | P | P | N | K | I | L | Y | I | I | Q | D | F | E | P | G | F | Y | Q | W | S | S | Q | Y | V | L | A | E | S | T | Y | K | Y | R | G | P | Q | I | A | V | F | N | S | E | L | L |
Template Known Secondary structure |   |
|
|  |  |  |
| T | T |  |  |  |  |  |
| S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
|
|
|
|  |  |  |  |  |
| S |
| G | G | G | G | S |
| S | S |  |  |  |  |  |  |  |  | T | T | S |
|
| S |
|  |  |  |  |  |  | S |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
126 | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . |
  |
  |   |
148 | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
I | A | D | F | Q | K | H | Y | Q | T | E | P | E | R | F | Q | I | L | P | P | G | I | Y | P | D | R | K | Y | S | E | Q | I | P | N | S | R | E | I | Y | R | Q | K | N | G | I | K | E | Q | Q | N | L | L | L | Q | V | G | S | D | F | G | R | K | G | V | D | R | S | I | E | A | L | A | S | L | P | E | S | L | R | H |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |
|   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |
|   |   |   | . |   |   |   |   |   |   |   |   |
|
|   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |
|
|   |   |   |
|
|
|   |   |   |
|
|   |   |   |
|
|   |
|   |   |   |
|   |   |   |   |   |   |
Template Sequence |   |
K | Q | Y | F | N | N | K | . |
G | Y | N | F | T | D | E | Y | F | F | Q | P | K | I | N | T | T | L | K | N | Y | I | N | D | K | R | Q | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
K | E | K | I | I | L | V | Y | G | R | P | S | V | K | R | N | A | F | T | L | I | V | E | A | L | K | I | F | V | Q | K | Y | D | R |
Template Known Secondary structure |   |
 |  |  |  |  |  |  | . | T |
|
|
| S |  |  |  |  |  |
|
|
|
|
|  |  |  |  | T | T | T | T | S |
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
| S |  |  |  |  |  |  |
| T | T |
| G | G | G |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| T | T |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  | . |
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
206 | . | . | . | 210 | . | . | |
. | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . |
  |
  |   |
228 | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
N | T | L | L | F | V | V | G | Q | D | K | P | R | K | F | E | A | L | A | E | K | L | G | V | R | S | N | V | H | F | F | S | G | R | N | D | V | S | E | L | M | A | A | A | D | L | L | L | H | P | A | Y | Q | E | A | A | G | I | V | L | L | E | A | I | T | A | G | L | P | V | L | T | T | A | V | C | G | Y | A | H |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |
|
|
|
|   |
|   |
|
|
|   |
|   |   |   |
|   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
Template Conservation |   |
  |   |   |
|   |
|   |
|   |
|   |   |   |   |   |   |   | . | . |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |
|
|   |   |
|   |   |   |
|
|
|   |
|   |
|
|   |   |
|   |   |   |   |   |   |
|
|
|
|
|   |
|   |
|
|
|   |
|   | . |   |
|   |   |   |
Template Sequence |   |
S | N | E | W | K | I | I | S | V | G | E | K | H | K | D | I | A | . |
. |
L | G | K | G | I | H | L | N | S | L | G | K | L | T | L | E | D | Y | A | D | L | L | K | R | S | S | I | G | I | S | L | X | I | S | P | H | P | S | Y | P | P | L | E | X | A | H | F | G | L | R | V | I | T | N | K | . |
Y | E | N | K | D |
Template Known Secondary structure |   |
G | G | G |
|  |  |  |  |  |  | S |
|
|
|
|  |  | . | . |  |  | T | T |  |  |  |  |  |  |  | S |
|
|  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |
|
|
| S | S | S | S |
|
| S |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |
| . | B | T | T | B |
|
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  | . | . |
|
|
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
| . |
|
|
|  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
274 | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | |
|
. | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | |
. | . | . | . | 350 |
  |
  |   |
308 | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Y | I | A | D | A | N | C | G | T | V | I | A | E | P | F | S | Q | E | Q | L | N | E | V | L | R | K | A | L | T | Q | S |
Query Conservation |   |
  |
|   |   |   |   |   |
|   |
|   |   |   |   |   |
|   |   |   |
|
|   |
|
|   |   |
|
|   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |
| . |   |   |   |   |   |   |   |
|
|   |
|
|   |   |
|   |   |   |   |
Template Sequence |   |
L | S | N | W | H | S | N | I | V | S | L | . |
E | Q | L | N | P | E | N | I | A | E | T | L | V | E | L | C | X | S | F |
Template Known Secondary structure |   |
G | G | G | T | B | T | T |  |  |  |  | . | S | S |
| S |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
Template Predicted Secondary structure |   |
 |  |
|
|
|
|
|  |  |  |  | . |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
351 | . | . | . | . | . | . | . | . | 360 | . | |
. | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 |
  |