|   |
377 | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | |
|
|
. | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
| . | . | . |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | F | G | E | I | I | G | R | S | E | A | M | Y | S | V | L | K | Q | V | E | M | V | A | Q | S | D | S | T | . |
. |
. |
V | L | I | L | G | E | T | G | T | G | K | E | L | I | A | R | A | I | H | N | L | S | G | R | N | N | R | R | M | V | K | M | N | C | A | A | M | P | A | G | L | L | E | S | D | L | F | G | H |
Query Conservation |   |
  |   |   |   |
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
| . | . | . |
|
|
|   |
|
|   |
|
|
|
|   |   |   |
|   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
Template Conservation |   |
  |   |   |
|   |
|
|   |
|   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |
|
|
|
|
|
|
|
|   |
|
|   |   |
|
|   |   | . | . | . |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . |
Template Sequence |   |
S | L | D | E | F | I | G | Q | E | N | V | K | K | K | L | S | L | A | L | E | A | A | K | M | R | G | E | V | L | D | H | V | L | L | A | G | P | P | G | L | G | K | T | T | L | A | H | I | I | A | S | E | . |
. |
. |
L | Q | T | N | I | H | V | T | S | G | P | V | L | V | K | Q | G | D | M | A | A | I | . |
. |
. |
Template Known Secondary structure |   |
S | G | G | G |
|
| S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
|
|
|
|  |  |  |  | S | S | T | T | S | S |  |  |  |  |  |  |  |  |  |  |  | . | . | . |  | T |
|
|  |  |  |  |  | T | T | T |
|
| S |  |  |  |  |  |  |  | . | . | . |
Template Predicted Secondary structure |   |
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  | . | . | . |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
23 | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | |
|
|
. | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | |
|
|
  |
  |   |
454 | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |
|  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
|
|
|
|
|  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | R | G | A | F | T | G | A | S | A | Q | R | I | G | R | F | E | L | A | D | K | S | S | L | F | L | D | E | V | G | D | M | P | L | E | L | Q | P | K | L | L | R | V | L | Q | E | Q | E | F | E | R | L | G | S | N | K | I | I | Q | T | D | V | R | L | I | A | A | T | N | R | D | L | K | K | M | V | A | D | R | E |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|
|   |
|   |   |
|   |   |
|   |   |   |   |
|   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |
|
|   |   |
|
|
|   |   |
|   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
L | T | S | L | E | R | G | D | V | L | F | I | D | E | I | H | R | L | N | K | A | V | E | E | L | L | Y | S | A | I | E | D | F | Q | . |
. |
. |
. |
. |
. |
. |
I | D | I | Q | P | F | T | L | V | G | A | T | V | R | S | G | L | L | S | S | P | L | R | S | R |
Template Known Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  | T |
|
| T | T |
|  |  |  |  |  | T | G | G | G |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | S |
| . | . | . | . | . | . | . |
|
|
|
|
|
|  |  |  |  |  |  | S |
| G | G | G | S |
|  |  |  |  | T | T |
Template Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| . | . | . | . | . | . | . |
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
97 | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | |
|
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . |
  |
  |   |
534 | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . | . | . | . | . | . | . | 610 | . | . | . |
Predicted Secondary structure |   |
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
F | R | S | D | L | Y | Y | R | L | N | V | F | P | I | H | L | P | P | L | R | E | R | P | E | D | I | P | L | L | A | K | A | F | T | F | K | I | A | R | R | L | G | R | N | I | D | S | I | P | A | E | T | L | R | T | L | S | N | M | E | W | P | G | N | V | R | E | L | E | N | V | I | E | R | A | V | L | L | T | R |
Query Conservation |   |
  |   |   |   |
|   |   |   |
|   |   |   |   |
|   |
|
|
|
|
|
|
|   |
|
|
|   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |
|
|
|
|   |   |
|
|   |   |   |
|   |   |   |   |   |   |   |   |
Alig confidence |   |
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . |   |   |   |   |   |   |   |   |
|   |   |   | . |   |   |
|   |   |
|   |   |   |   |
|
|   |   |   |   |   |   |   |   |
Template Sequence |   |
F | . |
. |
. |
. |
. |
. |
. |
. |
. |
G | I | I | L | E | L | D | F | Y | T | . |
. |
. |
. |
. |
. |
V | K | E | L | K | E | I | I | K | R | A | A | S | L | M | D | V | E | . |
. |
. |
I | E | D | A | A | A | E | M | I | A | K | R | . |
S | R | G | T | P | R | I | A | I | R | L | T | K | R | V | R | D | M | L | T |
Template Known Secondary structure |   |
| . | . | . | . | . | . | . | . | . | S |  |  |  |  |
|
|
|
|
| . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
| . | . | . | B |
|  |  |  |  |  |  |  |  |  | T | . | S | T | T |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 | . | . | . | . | . | . | . | . | . |  |  |  |
|
|
|
|
|
|
| . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
| . | . | . |
|
|  |  |  |  |  |  |  |  |  |  | . |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
171 | |
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | 180 | . | |
|
|
|
|
|
. | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | |
|
|
200 | . | . | . | . | . | . | . | . | . | 210 | . | |
. | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . |
  |
  |   |
|
|
|
614 | . | . | . | . | . | 620 | . | . | . | . | . | . | . | . | . | 630 | . | . | . | . | . | . | . | . | . | 640 | . | . | . | . | . | . | . | . | . | 650 | . | . | . | . | . | . | . | . | . | 660 | . | . | . | . | . | . | . | . | . | 670 | . | . | . | . | . | . | . | . | . | 680 | . | . | . | . |
Predicted Secondary structure |   |
. | . | . |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
Query SS confidence |   |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
G | N | V | L | Q | L | S | L | P | D | I | V | L | P | E | P | E | T | P | P | A | A | T | V | V | A | L | E | G | E | D | E | Y | Q | L | I | V | R | V | L | K | E | T | N | G | V | V | A | G | P | K | G | A | A | Q | R | L | G | L | K | R | T | T | L | L | S | R | M | K | R | L |
Query Conservation |   |
. | . | . |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|
|   |   |   |   |
|   |   |   |
|   |   |   |
|
|   |   |
|
|
|   |
|   |
|
|   |
|
|
|
|   |   |
Alig confidence |   |
. | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
V | V | K | A | D | R | I | N | T | D | I | V | L | K | T | M | E | V | L | N | I | D | D | E | G | L | D | . |
. |
. |
. |
. |
E | F | D | R | K | I | L | K | T | I | I | E | I | Y | R | G | G | P | V | G | L | N | A | L | A | A | S | L | G | V | E | A | D | T | L | S | E | V | Y | E | P | Y |
Template Known Secondary structure |   |
 |  | T |
| S | S | B |
|  |  |  |  |  |  |  |  |  |  |  | T |
|
| T | T |
|
|
| . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  | S | T | T |
|
| B |
|  |  |  |  |  |  |  |  | T | S |
|  |  |  |  |  |  | T | T |  |  |  |
Template Predicted Secondary structure |   |
 |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
232 | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | |
|
|
|
|
. | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 |
  |