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Job DescriptionP31447
Confidence100.00%DateThu Jan 5 11:47:37 GMT 2012
Rank19Aligned Residues257
% Identity19%Templatec2xrgA_
PDB info PDB header:hydrolaseChain: A: PDB Molecule:ectonucleotide pyrophosphatase/phosphodiesterase family PDBTitle: crystal structure of autotaxin (enpp2) in complex with the2 ha155 boronic acid inhibitor
Resolution3.20 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


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Query Sequence  KRPNFLFVMTDTQATNMVGCYSGKPLNTQNIDSLAAEGIRFNSAYTCSP. VCTPARAGLFTGIYANQSGPWTNNVAPGK.
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Template Sequence  VRPPLIIFSVDGFRASYMKKGSKV. . . MPNIEKLRSCGTHAPYMRPVYPTKTFPNLYTLATGLYPESHGIVGNSMYDPVF
Template Known Secondary structure  SS

T

GGGGGS
TTT...SS
S


SS
S
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S


SSTTT
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   161........170.........180.... .....190.........200.........210.........220.........230.......
 
   80.........90.........100.........110.........120.........130.........140..
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Query Sequence  . . . . . . . . . . . . . . . . . NISTMGRYFKDAGYHTCYIGKWHLDGHDYFGTGECPPEWDADYWFDGANYLSELTEKEISLWR
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Template Sequence  DASFHLRGREKFNHRWWGGQPLWITATKQGVRAGTF. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Template Known Secondary structure  T
SSSSGGG
TTS

S

TTT

B


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   143......150.........160.........170.........180.........190.........200.........210.........220..
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Query Sequence  NGLNSVEDLQANHIDETFTWAHRISNRAVDFLQQPARADEPFLMVVSYDEPHHPFTCPVEYLEKYADFYYELGEKAQDDL
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Template Sequence  . . . . . . . . . . . . . FWSVSIPHERRILTILQWLSLP. DNERPSVYAFYSEQPD. . . . . . . FSGHKYGPFGPE. . . . . . . . .
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TTS
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Query Sequence  ANKPEHHRLWAQAMPSPVGDDGLYHHPLYFACNDFVDDQIGRVINALTPEQR. ENTWVIYTSDHG. . . . . . . . . . . . . . .
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Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . MTNPLREIDKTVGQLMDGLKQLRLHRCVNVIFVGDHGMEDVTCDRTEFLSNY
Template Known Secondary structure  ............................GTT
TTT
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SSSGGGT
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   324.....330.........340.........350.........360.........370.....
 
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . EMMGAHKLIS.
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Template Sequence  LTNVDDITLVPGTLGRIRAKYDPKTIIAALTCKKPDQHFKPYMKQHLPKRLHYANNRRIEDIHLLVDRRWHVARKPFQGD
Template Known Secondary structure 
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TT
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   376...380.........390.........400.........410.........420.........430.........440.........450.....
 
   297..300.........310.........320.........330.........340. ........350.........360...
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Query Sequence  KGAAMYDDITRIPLIIRSPQGERRQVDTPVSHIDLLPTMMALADI. EKPEILPGENILAVKEPRGVMV
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Template Sequence  HGFDNKVNSMQTVFVGYGPTFKYRTKVPPFENIELYNVMCDLLGLKPAPNNGTHGSLNHLLRTNTFRP
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S
TT
GGG
B
SSSB
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S
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   474.....480.........490.........500.........510.........520.........530.........540.
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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